Search Results - "Onwuamah, Chika"

Full length genomic sanger sequencing and phylogenetic analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Nigeria by Shaibu, Joseph Ojonugwa, Onwuamah, Chika K, James, Ayorinde Babatunde, Okwuraiwe, Azuka Patrick, Amoo, Olufemi Samuel, Salu, Olumuyiwa B, Ige, Fehintola A, Liboro, Gideon, Odewale, Ebenezer, Okoli, Leona Chika, Ahmed, Rahaman A, Achanya, Dominic, Adesesan, Adesegun, Amuda, Oyewunmi Abosede, Sokei, Judith, Oyefolu, Bola A O, Salako, Babatunde Lawal, Omilabu, Sunday Aremu, Audu, Rosemary Ajuma

“…In an outbreak, effective detection of the aetiological agent(s) involved using molecular techniques is key to efficient diagnosis, early prevention and…”
Get full text

SARS-COV-2 antibody responses to AZD1222 vaccination in West Africa by Abdullahi, Adam, Oladele, David, Owusu, Michael, Kemp, Steven A., Ayorinde, James, Salako, Abideen, Fink, Douglas, Ige, Fehintola, Ferreira, Isabella A. T. M., Meng, Bo, Sylverken, Augustina Angelina, Onwuamah, Chika, Boadu, Kwame Ofori, Osuolale, Kazeem, Frimpong, James Opoku, Abubakar, Rufai, Okuruawe, Azuka, Abdullahi, Haruna Wisso, Liboro, Gideon, Agyemang, Lawrence Duah, Ayisi-Boateng, Nana Kwame, Odubela, Oluwatosin, Ohihoin, Gregory, Ezechi, Oliver, Kamasah, Japhet Senyo, Ameyaw, Emmanuel, Arthur, Joshua, Kyei, Derrick Boakye, Owusu, Dorcas Ohui, Usman, Olagoke, Mogaji, Sunday, Dada, Adedamola, Agyei, George, Ebrahimi, Soraya, Gutierrez, Lourdes Ceron, Aliyu, Sani H., Doffinger, Rainer, Audu, Rosemary, Adegbola, Richard, Mlcochova, Petra, Phillips, Richard Odame, Solako, Babatunde Lawal, Gupta, Ravindra K.

“…Real-world data on vaccine-elicited neutralising antibody responses for two-dose AZD1222 in African populations are limited. We assessed baseline SARS-CoV-2…”
Get full text

Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria by Rawizza, Holly E, Chaplin, Beth, Meloni, Seema T, Darin, Kristin M, Olaitan, Oluremi, Scarsi, Kimberly K, Onwuamah, Chika K, Audu, Rosemary A, Chebu, Philippe R, Imade, Godwin E, Okonkwo, Prosper, Kanki, Phyllis J

“…To date, antiretroviral therapy (ART) guidelines and programs in resource-limited settings (RLS) have focused on 1(st)- and 2(nd)-line (2 L) therapy. As…”
Get full text

Exposure of Allium cepa root cells to zidovudine or nevirapine induces cytogenotoxic changes by Onwuamah, Chika K, Ekama, Sabdat O, Audu, Rosemary A, Ezechi, Oliver C, Poirier, Miriam C, Odeigah, Peter G C

“…Antiretroviral drugs have proved useful in the clinical management of HIV-infected persons, though there are concerns about the effects of exposure to these…”
Get full text

The use of DIY (Do it yourself) sampling and telemonitoring model for COVID-19 qPCR testing scale up by Amoo, Olufemi Samuel, Adewara, Funmi, Tijani, Bosun, Onuigbo, Tochukwu Ifeanyi, Ikemefuna, Amaka Stephanie, Oraegbu, Joy Isioma, Rizvi, Tazeen, Okwuraiwe, Azuka, Onwuamah, Chika, Shaibu, Joseph, James, Ayorinde, Ohihoin, Greg, Ige, Fehintola, Kareithi, Dorcas, David, Agatha, Karera, Steven, Agboola, Hammed, Adeniyi, Anthony, Obi, Josephine, Achanya, Dominic, Odewale, Ebenezer, Oforomeh, Osaga, Liboro, Gideon, Nwogbe, Olayemi, Ezechi, Oliver, Adegbola, Richard, Audu, Rosemary, Salako, Babatunde

“…The first case of COVID-19 in Nigeria was recorded on February 27, 2020, being an imported case by an Italian expatriate, to the country. Since then, there has…”
Get full text

High prevalence of resistance to third-generation cephalosporins detected among clinical isolates from sentinel healthcare facilities in Lagos, Nigeria by Chukwu, Emelda E, Awoderu, Oluwatoyin B, Enwuru, Christian A, Afocha, Ebelechukwu E, Lawal, Rahman G, Ahmed, Rahaman A, Olanrewaju, Ishola, Onwuamah, Chika K, Audu, Rosemary A, Ogunsola, Folasade T

“…Antimicrobial resistance (AMR) in bacterial pathogens is a worldwide concern that demands immediate attention. Most information on AMR originates from…”
Get full text

Laboratory Optimization Tweaks for Sanger Sequencing in a Resource-Limited Setting by Onwuamah, Chika K, Okwuraiwe, Azuka P, Ahmed, Rahaman A, Sokei, Judith O, Ponmak, Jamda, Okoli, Leona C, Kagurusi, Brian A, Anejo-Okopi, Joseph

“…Despite various challenges that hinder the implementation of high-tech molecular methods in resource-limited settings, we have been able to implement and…”
Get full text

Genotyping performance evaluation of commercially available HIV-1 drug resistance test by Rosemary, Audu, Chika, Onwuamah, Jonathan, Okpokwu, Godwin, Imade, Georgina, Odaibo, Azuka, Okwuraiwe, Zaidat, Musa, Philippe, Chebu, Oliver, Ezechi, Oche, Agbaji, David, Olaleye, Jay, Samuel, Ibrahim, Dalhatu, Mukhtar, Ahmed, Joshua, DeVos, Chunfu, Yang, Elliot, Raizes, Beth, Chaplin, Phyllis, Kanki, Emmanuel, Idigbe

“…ATCC HIV-1 drug resistance test kit was designed to detect HIV-1 drug resistance (HIVDR) mutations in the protease and reverse transcriptase genes for all…”
Get full text

Low levels of HIV-1 drug resistance mutations in patients who achieved viral re-suppression without regimen switch: a retrospective study by Onwuamah, Chika K, Okpokwu, Jonathan, Audu, Rosemary, Imade, Godwin, Meloni, Seema T, Okwuraiwe, Azuka, Chebu, Philippe, Musa, Adesola Z, Chaplin, Beth, Dalhatu, Ibrahim, Agbaji, Oche, Samuels, Jay, Ezechi, Oliver, Ahmed, Mukhtar, Odaibo, Georgina, Olaleye, David O, Okonkwo, Prosper, Salako, Babatunde Lawal, Raizes, Elliot, Yang, Chunfu, Kanki, Phyllis J, Idigbe, Emmanuel O

“…We identified a HIV-positive cohort in virologic failure (VF) who re-suppressed without drug switch. We characterized their drug resistance mutations (DRM) and…”
Get full text

Foetal loss and enhanced fertility observed in mice treated with Zidovudine or Nevirapine by Onwuamah, Chika K, Ezechi, Oliver C, Herbertson, Ebiere C, Audu, Rosemary A, Ujah, Innocent A O, Odeigah, Peter G C

“…Health concerns for HIV-infected persons on antiretroviral therapy (ART) have moved from morbidity to the challenges of long-term ART. We investigated the…”
Get full text

Novel GREM1 Variations in Sub-Saharan African Patients With Cleft Lip and/or Cleft Palate by Gowans, Lord Jephthah Joojo, Oseni, Ganiyu, Mossey, Peter A., Adeyemo, Wasiu Lanre, Eshete, Mekonen A., Busch, Tamara D., Donkor, Peter, Obiri-Yeboah, Solomon, Plange-Rhule, Gyikua, Oti, Alexander A., Owais, Arwa, Olaitan, Peter B., Aregbesola, Babatunde S., Oginni, Fadekemi O., Bello, Seidu A., Audu, Rosemary, Onwuamah, Chika, Agbenorku, Pius, Ogunlewe, Mobolanle O., Abdur-Rahman, Lukman O., Marazita, Mary L., Adeyemo, A. A., Murray, Jeffrey C., Butali, Azeez

“…Objective: Cleft lip and/or cleft palate (CL/P) are congenital anomalies of the face and have multifactorial etiology, with both environmental and genetic risk…”
Get full text

Serum concentrations of IL-16 and its genetic polymorphism rs4778889 affect the susceptibility and severity of endometriosis in Nigerian women by Babah, Ochuwa Adiketu, Ojewunmi, Oyesola Oyewole, Onwuamah, Chika Kingsley, Udenze, Ifeoma Christiana, Osuntoki, Akinniyi Adediran, Afolabi, Bosede Bukola

“…Endometriosis is the presence of active ectopic endometrial glands and stroma at other sites outside the uterine cavity. It is a common cause of chronic pelvic…”
Get full text

Comparative performance of SARS-CoV-2 real-time PCR diagnostic assays on samples from Lagos, Nigeria by Onwuamah, Chika Kingsley, Okwuraiwe, Azuka Patrick, Salu, Olumuyiwa B, Shaibu, Joseph O, Ndodo, Nnaemeka, Amoo, Samuel O, Okoli, Leona C, Ige, Fehintola A, Ahmed, Rahaman A, Bankole, Munir Akinwale, Sokei, Judith O, Mutiu, Bamidele Paul, Ayorinde, James, Saka, Babatunde Akeem, Obiekea, Celestina, Mba, Nwando, Adegbola, Richard A, Omilabu, Sunday, Ihekweazu, Chikwe, Salako, Babatunde Lawal, Audu, Rosemary

“…A key element in containing the spread of the SARS-CoV-2 infection is quality diagnostics which is affected by several factors. We now report the comparative…”
Get full text

Low level SARS-CoV-2 RNA detected in plasma samples from a cohort of Nigerians: Implications for blood transfusion by Okwuraiwe, Azuka Patrick, Onwuamah, Chika Kingsley, Shaibu, Joseph Ojonugwa, Amoo, Samuel Olufemi, Ige, Fehintola Anthonia, James, Ayorinde Babatunde, Okoli, Leona Chika, Ahmed, Abul-Rahman, Ponmak, Jamda, Sokei, Judith O, Akanmu, Sulaimon, Salako, Babatunde Lawal, Audu, Rosemary Ajuma

“…The present global pandemic triggered by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has lingered for over a year in its devastating…”
Get full text

Molecular detection of hepatitis B virus genotype E with immune escape mutations in chronic hepatitis B patients on long-term antiviral therapy in Jos, Nigeria by Anejo-Okopi, Joseph, Okeke, Edith, Davwar, Pantong M., Onwuamah, Chika, Onywera, Harris, Omaiye, Patience, Duguru, Mary, Okojokwu, Ocheme J., Ujah, Otobo I., Jonathan, Bulus, George, Chima A., Crown, Ramyil S., Yakubu, Fiyaktu B., Sokei, Judith O., Okoli, Leona C., Audu, Onyemocho, Inzaule, Seth C., Abah, Isaac O., Agaba, Patricia, Agbaji, Oche O., Sagay, Atiene S., Hawkins, Claudia

“…Background Previous studies in Nigeria have reported the presence of hepatitis B virus (HBV) genotype E and the availability of immune escape mutants. There is…”
Get full text

Self-collected versus medic-collected sampling for human papillomavirus testing among women in Lagos, Nigeria: a comparative study by Feng, Ning, Ezechi, Oliver, Uwandu, Mabel, Abimbola, Bowofoluwa Sharon, Vincent, Grace Deborah, Idigbe, Ifeoma, Okoli, Leona Chika, Adesina, Mary, Okwuzu, Jane, Ahmed, Rahaman Ademolu, Sokei, Judith, Shaibu, Joseph Ojonugwa, Momoh, Abidemi Esther, Sowunmi, Omowunmi, Labo-Popoola, Olaoniye Habeebat, Sunday, Mfon Victoria, Fayemi, Janet, Udoh, Hannah Mfon, Omidiji, Mayokun, Ogundepo, Oluwatobi, Ogbolu, Victor

“…Abstract Objective To evaluate the feasibility and performance of self-collected vaginal swab samples for HPV screening among women in Lagos, Nigeria. Methods…”
Get full text

Mechanism of Viral Suppression among HIV Elite Controllers and Long-Term Nonprogressors in Nigeria and South Africa by Ahmed, Rahaman Ademolu, Adekoya, Khalid Olajide, Onwuamah, Chika Kingsley, Oboh, Bolanle Olufunmilayo, Iyer, Smita Swaminathan, Oluwatosin, Ayomide Samuel, Audu, Rosemary Ajuma, Ezechi, Oliver Chukwujekwu

“…A subgroup among people living with HIV (PLHIV) experience viral suppression, sometimes to an undetectable level in the blood and/or are able to maintain a…”
Get full text

Prevalence and risk factors for high-risk human papillomavirus infection among women from three southern geopolitical zones of Nigeria by Onwuamah, Chika Kingsley, Feng, Ning, Momoh, Abidemi Esther, Uwandu, Mabel, Ahmed, Rahaman Ademolu, Idigbe, Ifeoma, Vincent, Grace Deborah, Ogbu, Chinenye Angela, Okonkwo, Nkem, Sokei, Judith, Abimbola, Bowofoluwa Sharon, Ojopagogo, Temiloluwa, Okoli, Leona Chika, Adesina, Mary, Ezemelue, Priscilla Ngozi, Sowunmi, Omowunmi, Okwuzu, Jane, Labo Popoola, Olaoniye Habeebat, Shaibu, Joseph Ojonugwa, Ohihoin, Greg Aigbe, Nzeribe, Emily, David, Agatha, Olaleye, Olufemi, Ofotokun, Ighovwerha, Dong, Xiao Ping, Ezechi, Oliver Chukwujekwu

“…Human Papillomavirus (HPV) infection is a risk factor for cervical cancer, the fourth most common cancer among women globally. Its burden is the highest in…”
Get full text

SARS-CoV-2 sequencing collaboration in west Africa shows best practices by Onwuamah, Chika Kingsley, Kanteh, Abdoulie, Abimbola, Bowofoluwa Sharon, Ahmed, Rahaman Ademolu, Okoli, Chika Leona, Shaibu, Joseph Ojonugwa, James, Ayorinde B, Ajibaye, Olusola, Okwuraiwe, Azuka P, Fowora, Muinah, Otuonye, Ngozi, Worwui, Archibald, Iwalokun, Bamidele, Kanteh, Dembo, Audu, Rosemary A, Adegbola, Richard Adebayo, D'Alessandro, Umberto, Salako, Babatunde Lawal, Sesay, Abdul Karim

Get full text

Multidisciplinary approach to genomics research in Africa: the AfriCRAN model by Butali, Azeez, Mossey, Peter, Tiffin, Nikki, Adeyemo, Wasiu, Eshete, Mekonen, Mumena, Chrispinanus, Audu, Rosemary, Onwuamah, Chika, Agbenorku, Pius, Ogunlewe, Mobolanle, Adebola, Adetokunbo, Olasoji, Hecto, Aregbesola, Babatunde, Braimah, Ramat, Oladugba, Abimibola, Onah, Ifeanyichukwu, Adebiyi, Ezekiel, Olaitan, Peter, Abdur-Rahman, Lukman, Adeyemo, Adebowale

“…This article is an outcome of the African Craniofacial Anomalies Research Network (AfriCRAN) Human Hereditary and Health (H3A) grant planning meeting in 2012…”
Get full text