Search Results - "Onozaki, K"

Smad3 is acetylated by p300 CBP to regulate its transactivation activity by INOUE, Y, ITOH, Y, ABE, K, OKAMOTO, T, DAITOKU, H, FUKAMIZU, A, ONOZAKI, K, HAYASHI, H

“…Smad proteins are crucial for the intracellular signaling of transforming growth factor-beta (TGF-beta). Upon their receptor-induced activation, Smad proteins…”
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Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes by Matsumura, T, Ito, A, Takii, T, Hayashi, H, Onozaki, K

“…Toll-like receptor (TLR) 2 and TLR4 are members of the interleukin-1 receptor (IL-1R) family and transduce similar signals as IL-1R in response to bacteria and…”
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Human interleukin 1 is a cytocidal factor for several tumor cell lines by Onozaki, K, Matsushima, K, Aggarwal, BB, Oppenheim, JJ

“…Highly purified interleukin 1 (IL 1) obtained from stimulated human monocytes appeared to be growth inhibitory and cytocidal for a human melanoma cell line,…”
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Apamin-Sensitive Ca2+-Dependent K+Current and Hyperpolarization in Human Endothelial Cells by Muraki, K., Imaizumi, Y., Ohya, S., Sato, K., Takii, T., Onozaki, K., Watanabe, M.

“…Vascular endothelial cells have several types of Ca2+-dependent K+current (IK-Ca). Here, we describe apamin-sensitive IK-Cawhich is activated by treatment with…”
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Serotonin derivative, N-(p-Coumaroyl) serotonin, isolated from safflower (Carthamus tinctorius L.) oil cake augments the proliferation of normal human and mouse fibroblasts in synergy with basic fibroblast growth factor (bFGF) or epidermal growth factor (EGF) by Takii, T, Hayashi, M, Hiroma, H, Chiba, T, Kawashima, S, Zhang, H.L, Nagatsu, A, Sakakibara, J, Onozaki, K

“…N-(p-Coumaroyl)serotonin (CS) with antioxidative activity is present in safflower oil. We have reported that CS inhibits proinflammatory cytokine generation…”
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Activation of two distinct anti-proliferative pathways, apoptosis and p38 MAP kinase-dependent cell cycle arrest, by tumor necrosis factor in human melanoma cell line A375 by Hattori, T, Hayashi, H, Chiba, T, Onozaki, K

“…The proliferation of human melanoma cell line A375-6 cells is inhibited by several cytokines, including interleukin-1 (IL-1). A375-R8 cells, a subclone of…”
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Regulation by dietary essential fatty acid balance of tumor necrosis factor production in mouse macrophages by Watanabe, S, Onozaki, K, Yamamoto, S, Okuyama, H

“…Increasing the dietary alpha-linolenate (18:3n - 3)/linoleate (18:2n - 6) ratio results in an increase in lipopolysaccharide (LPS)-stimulated tumor necrosis…”
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Dietary docosahexaenoic acid but not eicosapentaenoic acid suppresses lipopolysaccharide-induced interleukin-1β mRNA induction in mouse spleen leukocytes by Watanabe, S., Katagiri, K., Onozaki, K., Hata, N., Misawa, Y., Hamazaki, T., Okuyama, O.

“…Mice were fed a diet supplemented either with beef tallow (BT), BT plus ethyl eicosapentaenoate (EPA) or BT plus ethyl docosahexaenoate (DHA) for 9 weeks. EPA…”
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Interleukin 1 (IL-1) by Onozaki, K

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CHOP, a basic leucine zipper transcriptional factor, contributes to the antiproliferative effect of IL-1 on A375 human melanoma cells through augmenting transcription of IL-6 by Hattori, T, Itoh, S, Hayashi, H, Chiba, T, Takii, T, Yoshizaki, K, Onozaki, K

“…Interleukin-1 (IL-1) inhibits the proliferation of A375 human melanoma cells. We have demonstrated previously that p38 mitrogen-activated protein kinase (MAPK)…”
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Role of ornithine decarboxylase in the regulation of cell growth by IL- 1 and tumor necrosis factor by Endo, Y, Matsushima, K, Onozaki, K, Oppenheim, JJ

“…Ornithine decarboxylase (ODC) is a rate-limiting enzyme in polyamine synthesis, and polyamines are required for cell growth. As an approach to clarifying the…”
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Contribution of IL-6 to the antiproliferative effect of IL-1 and tumor necrosis factor on tumor cell lines by Morinaga, Y, Suzuki, H, Takatsuki, F, Akiyama, Y, Taniyama, T, Matsushima, K, Onozaki, K

“…The role of IL-6 in the antiproliferative effect of IL-1 for tumor cell lines was investigated using IL-1-sensitive cell lines. Human recombinant IL-1 alpha…”
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TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death by Ohoka, Nobumichi, Yoshii, Satoshi, Hattori, Takayuki, Onozaki, Kikuo, Hayashi, Hidetoshi

“…C/EBP homologous protein (CHOP) is a stress‐inducible nuclear protein that is crucial for the development of programmed cell death and regeneration; however,…”
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Alteration of the cellular response to interleukin-1β by SV40 large T antigen in rheumatoid synovial fibroblasts by ASAMITSU, K, SAKURADA, S, MASHIBA, K, NAKAGAWA, K, TORIKAI, K, ONOZAKI, K, OKAMOTO, T

“…The large T antigen of SV40 (LT) has been widely used to immortalize primary cells for various studies. In this study, synovial fibroblasts of a patient from…”
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Binding of Legionella pneumophila to macrophages increases cellular cytokine mRNA by YAMAMOTO, Y, OKUBO, S, KLEIN, T. W, ONOZAKI, K, SAITO, T, FRIEDMAN, H

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Interleukin-1 or tumor necrosis factor-alpha augmented the cytotoxic effect of mycobacteria on human fibroblasts: application to evaluation of pathogenesis of clinical isolates of Mycobacterium tuberculosis and M. avium complex by Takii, T, Abe, C, Tamura, A, Ramayah, S, Belisle, J T, Brennan, P J, Onozaki, K

“…Mycobacteria-induced in vitro events reflecting human tuberculosis can contribute to the evaluation of the pathogenesis of Mycobacterium tuberculosis (MTB). In…”
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Interleukin-1 (IL-1), IL-1 receptor, IL-1 receptor antagonist (IL-1ra) by Hayashi, H, Onozaki, K

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Role of interleukin 1 in promoting human monocyte-mediated tumor cytotoxicity by Onozaki, K, Matsushima, K, Kleinerman, ES, Saito, T, Oppenheim, JJ

“…Human peripheral blood monocytes from normal donors obtained by separation on a Percoll gradient showed considerable cytotoxicity against tumor cells when…”
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Alteration of the cellular response to interleukin-1ß by SV40 large T antigen in rheumatoid synovial fibroblasts by Asamitsu, K, Sakurada, S, Mashiba, K, Nakagawa, K, Torikai, K, Onozaki, K, Okamoto, T

“…The large T antigen of SV40 (LT) has been widely used to immortalize primary cells for various studies. In this study, synovial fibroblasts of a patient from…”
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Acquired resistance to the anti-proliferative effect of interleukin-1 and interleukin-6 is a recessive phenotype in A375 human melanoma cells by Itoh, S, Hayashi, H, Yang, D, Takii, T, Onozaki, K

“…The proliferation of human melanoma cell line A375-6 is inhibited by several cytokines, including interleukin-1 (IL-1) and interleukin-6 (IL-6). However,…”
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