Search Results - "Onguéné, Pascal Amoa"

The potential of anti-malarial compounds derived from African medicinal plants, part I: a pharmacological evaluation of alkaloids and terpenoids by Amoa Onguéné, Pascal, Ntie-Kang, Fidele, Lifongo, Lydia Likowo, Ndom, Jean Claude, Sippl, Wolfgang, Mbaze, Luc Meva'a

“…Traditional medicine caters for about 80% of the health care needs of many rural populations around the world, especially in developing countries. In addition,…”
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The potential of anti-malarial compounds derived from African medicinal plants: a review of pharmacological evaluations from 2013 to 2019 by Bekono, Boris D, Ntie-Kang, Fidele, Onguéné, Pascal Amoa, Lifongo, Lydia L, Sippl, Wolfgang, Fester, Karin, Owono, Luc C O

“…African Traditional Medicine (ATM) is used for the healthcare of about 80% of the rural populations of the continent of Africa. The practices of ATM make use…”
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Computational discovery of dual potential inhibitors of SARS‐CoV‐2 spike/ACE2 and Mpro: 3D-pharmacophore, docking-based virtual screening, quantum mechanics and molecular dynamics by Bekono, Boris D., Onguéné, Pascal Amoa, Simoben, Conrad V., Owono, Luc C. O., Ntie-Kang, Fidele

“…To find drugs against COVID-19, caused by the SARS-CoV-2, promising targets include the fusion of the viral spike with the human angiotensin-converting enzyme…”
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The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids by Ntie-Kang, Fidele, Onguéné, Pascal Amoa, Lifongo, Lydia L, Ndom, Jean Claude, Sippl, Wolfgang, Mbaze, Luc Meva'a

“…Malaria is currently a public health concern in many countries in the world due to various factors which are not yet under check. Drug discovery projects…”
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Virtualizing the p-ANAPL library: a step towards drug discovery from African medicinal plants by Ntie-Kang, Fidele, Amoa Onguéné, Pascal, Fotso, Ghislain W, Andrae-Marobela, Kerstin, Bezabih, Merhatibeb, Ndom, Jean Claude, Ngadjui, Bonaventure T, Ogundaini, Abiodun O, Abegaz, Berhanu M, Meva'a, Luc Mbaze

“…Natural products play a key role in drug discovery programs, both serving as drugs and as templates for the synthesis of drugs, even though the quantities and…”
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In silico toxicity profiling of natural product compound libraries from African flora with anti-malarial and anti-HIV properties by Onguéné, Pascal Amoa, Simoben, Conrad V., Fotso, Ghislain W., Andrae-Marobela, Kerstin, Khalid, Sami A., Ngadjui, Bonaventure T., Mbaze, Luc Meva’a, Ntie-Kang, Fidele

“…[Display omitted] •The manuscript discusses toxicity predictions for three datasets of naturally occurring metabolites.•One dataset includes about 500…”
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Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus by Duncan, Maggie C, Onguéné, Pascal Amoa, Kihara, Ibuki, Nebangwa, Derrick N, Naidu, Maya E, Williams, David E, Balgi, Aruna D, Andrae-Marobela, Kerstin, Roberge, Michel, Andersen, Raymond J, Niikura, Masahiro, Ntie-Kang, Fidele, Tietjen, Ian

“…The increasing prevalence of drug-resistant influenza viruses emphasizes the need for new antiviral countermeasures. The M2 protein of influenza A is a…”
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Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors by Tietjen, Ian, Ntie-Kang, Fidele, Mwimanzi, Philip, Onguéné, Pascal Amoa, Scull, Margaret A, Idowu, Thomas Oyebode, Ogundaini, Abiodun Oguntuga, Meva'a, Luc Mbaze, Abegaz, Berhanu M, Rice, Charles M, Andrae-Marobela, Kerstin, Brockman, Mark A, Brumme, Zabrina L, Fedida, David

“…The continued burden of HIV in resource-limited regions such as parts of sub-Saharan Africa, combined with adverse effects and potential risks of resistance to…”
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Identification of potential dipeptidyl peptidase IV inhibitors from the ConMedNP library by virtual screening, and molecular dynamics methods by Tsahnang Fofack, Hans Merlin, Mbah Bake, Maraf, Petry, Simon, Ateba, Baruch A., Amoa Onguéné, Pascal, Mohammad-Salim, Haydar, Ntie-Kang, Fidele, Mbaze, Luc Meva'a, Vakal, Serhii, Kenfack, Cyril A

“…In this study, we screened novel dipeptidyl peptidase IV (DPP4) inhibitors from the ConMedNP library consisting of 3507 molecules. Interestingly, molecular…”
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CamMedNP: building the Cameroonian 3D structural natural products database for virtual screening by Ntie-Kang, Fidele, Mbah, James A, Mbaze, Luc Meva'a, Lifongo, Lydia L, Scharfe, Michael, Hanna, Joelle Ngo, Cho-Ngwa, Fidelis, Onguéné, Pascal Amoa, Owono Owono, Luc C, Megnassan, Eugene, Sippl, Wolfgang, Efange, Simon M N

“…Computer-aided drug design (CADD) often involves virtual screening (VS) of large compound datasets and the availability of such is vital for drug discovery…”
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Computational discovery of dual potential inhibitors of SARS-CoV-2 spike/ACE2 and M pro : 3D-pharmacophore, docking-based virtual screening, quantum mechanics and molecular dynamics by Bekono, Boris D, Onguéné, Pascal Amoa, Simoben, Conrad V, Owono, Luc C O, Ntie-Kang, Fidele

“…To find drugs against COVID-19, caused by the SARS-CoV-2, promising targets include the fusion of the viral spike with the human angiotensin-converting enzyme…”
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Insight into the antioxidant and antiradical properties of colorotane sesquiterpenes extracted from Warburgia ugandensis: theoretical evaluation by Mbieda, Joelle Nadine, Lissouck, Daniel, Amoa Onguene, Pie Pascal, Ateba Amana, Baruch, Moto Ongagna, Jean, Toze, Flavien Aristide, Bikele Mama, Désiré

“…The present work is focused on the examination of two biological activities (antioxidant and antiradical properties) of colorotane sesquiterpenes extracted…”
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The potential of anti-malarial compounds derived from African medicinal plants, part III: an in silico evaluation of drug metabolism and pharmacokinetics profiling by Onguéné, Pascal Amoa, Ntie-Kang, Fidele, Mbah, James Ajeck, Lifongo, Lydia Likowo, Ndom, Jean Claude, Sippl, Wolfgang, Mbaze, Luc Meva′a

“…Background Malaria is an endemic disease affecting many countries in Tropical regions. In the search for compound hits for the design and/or development of new…”
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Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors: e0121099 by Tietjen, Ian, Ntie-Kang, Fidele, Mwimanzi, Philip, Onguene, Pascal Amoa, Scull, Margaret A, Idowu, Thomas Oyebode, Ogundaini, Abiodun Oguntuga, Meva'a, Luc Mbaze, Abegaz, Berhanu M, Rice, Charles M

“…The continued burden of HIV in resource-limited regions such as parts of sub-Saharan Africa, combined with adverse effects and potential risks of resistance to…”
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