Search Results - "Ongini, E"
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Nitric oxide‐donating statin improves multiple functions of circulating angiogenic cells
Published in British journal of pharmacology (01-09-2011)“…BACKGROUND AND PURPOSE Statins, a major component of the prevention of cardiovascular disease, aid progenitor cell functions in vivo and in vitro. Statins…”
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Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type‐1 diabetic mice
Published in British journal of pharmacology (01-04-2007)“…Background and purpose: Mature endothelial cells and their progenitors are dysfunctional in diabetes, resulting in deficient neovascularisation following…”
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A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs
Published in Experimental eye research (01-09-2011)“…The IOP lowering effects of NCX 139, a new chemical entity comprising latanoprost amide and a NO-donating moiety, were compared to those of the respective…”
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A(2A) adenosine receptors in human peripheral blood cells
Published in British journal of pharmacology (01-01-2000)Get full text
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P.11.3 Long term treatment with naproxcinod significantly improves skeletal and cardiac function in mdx mouse model of dystrophy
Published in Neuromuscular disorders : NMD (01-10-2013)“…There is evidence that nitric oxide (NO) plays a critical role in skeletal muscle. In Duchenne muscular dystrophy (DMD) patients and the mdx mouse model of…”
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Up-regulation of ORL-1 receptors in spinal tissue of allodynic rats after sciatic nerve injury
Published in European journal of pharmacology (28-06-2002)“…Nociceptin, acting through the opioid receptor-like 1 (ORL1) receptor, produces anti-nociception in several models of neuropathy. We examined the involvement…”
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A topical nitric oxide-releasing dexamethasone derivative: effects on intraocular pressure and ocular haemodynamics in a rabbit glaucoma model
Published in British journal of ophthalmology (01-11-2006)“…Background: Topical nitric oxide-releasing dexamethasone (NCX1021) may avoid the negative effects of dexamethasone phosphate. Aims: To obtain more information…”
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A novel nitric oxide-releasing statin derivative exerts an antiplatelet/antithrombotic activity and inhibits tissue factor expression
Published in Journal of thrombosis and haemostasis (01-11-2005)“…NO-releasing statins are new chemical entities, combining HMG-CoA reductase inhibition and slow NO release, that possess stronger anti-inflammatory and…”
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570 THE CINOD NCX 429 EXERTS ANTI-INFLAMMATORY EFFECTS IN ISOLATED HUMAN MONOCYTES AND MACROPHAGES
Published in Osteoarthritis and cartilage (2010)Get full text
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Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-01-1999)“…Three structurally related non-xanthine compounds, CGS 15943, ZM 241385 and SCH 58261, are potent A2A adenosine receptor antagonists and have been used as…”
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The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist
Published in The Journal of pharmacology and experimental therapeutics (01-02-1996)“…We have characterized the in vitro pharmacological profile of the new potent and selective A2a adenosine receptor antagonist SCH 58261…”
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Presenilin-1 Regulates the Neuronal Threshold to Excitotoxicity Both Physiologically and Pathologically
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-2000)“…A direct pathophysiological role of Familial Alzheimer's Disease (FAD)-associated Presenilin 1 (PS1) mutations in neuronal vulnerability remains a…”
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Inhibitory Effect of NO-Releasing Ciprofloxacin (NCX 976) on Mycobacterium tuberculosis Survival
Published in Antimicrobial Agents and Chemotherapy (01-07-2003)“…ERRATUM ( vol. 48 , p. 368 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Nociceptin and the ORL‐1 ligand [Phe1ψ (CH2‐NH)Gly2]nociceptin(1‐13)NH2 exert anti‐opioid effects in the Freund's adjuvant‐induced arthritic rat model of chronic pain
Published in British journal of pharmacology (01-11-1999)“…Stimulation of the opioid receptor‐like1 (ORL‐1) receptor by nociceptin (NC) produces hyperalgesia and reverses the antinociceptive effects induced by opioids…”
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Lack of the nociceptin receptor does not affect acute or chronic nociception in mice
Published in Peptides (New York, N.Y. : 1980) (01-09-2002)“…The peptide nociceptin/orphanin FQ (N/OFQ) and its receptor ORL-1, also designated opioid receptor 4 (OP 4) are involved in the modulation of nociception…”
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Binding of the radioligand [3H]‐SCH 58261, a new non‐xanthine A2A adenosine receptor antagonist, to rat striatal membranes
Published in British journal of pharmacology (01-04-1996)“…1 The present study describes the binding to rat striatal A2A adenosine receptors of the new potent and selective antagonist radioligand,…”
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Differential effects of dopamine D-1 and D-2 receptor antagonist antipsychotics on sleep-wake patterns in the rat
Published in The Journal of pharmacology and experimental therapeutics (01-08-1993)“…A series of antipsychotics having different selectivity for dopamine (DA) D-1 and D-2 receptors were studied for their effects on sleep stages in the rat…”
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Inhibitory Effect of NO-Releasing Ciprofloxacin (NCX 976) on Mycobacterium tuberculosis Survival
Published in Antimicrobial agents and chemotherapy (01-01-2004)Get full text
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Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2011)“…Background & Aims Proton pump inhibitors (PPIs) and nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used classes of drugs, with the…”
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