Search Results - "Ong, Wilson W. S"
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c‑di-GMP Induces COX‑2 Expression in Macrophages in a STING-Independent Manner
Published in ACS chemical biology (17-09-2021)“…Many pathogen-associated molecular patterns (PAMPs), such as lipopolysaccharide (LPS) and lipoteichoic acid, are potent immunostimulatory molecules and promote…”
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Bacterial Cyclic Dinucleotides and the cGAS-cGAMP-STING Pathway: A Role in Periodontitis?
Published in Pathogens (Basel) (30-05-2021)“…Host cells can recognize cytosolic double-stranded DNAs and endogenous second messengers as cyclic dinucleotides-including c-di-GMP, c-di-AMP, and cGAMP-of…”
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A STING-based fluorescent polarization assay for monitoring activities of cyclic dinucleotide metabolizing enzymes
Published in RSC chemical biology (01-02-2021)“…Cyclic dinucleoties, such as cGAMP, c-di-GMP and c-di-AMP, are fascinating second messengers with diverse roles in both prokaryotes and eukaryotes…”
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STING antagonists, synthesized via Povarov-Doebner type multicomponent reaction
Published in RSC medicinal chemistry (22-06-2023)“…The cGAS-STING axis plays an important role in protecting higher organisms against invading pathogens or cancer by promoting the production of cytokines and…”
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STING antagonists, synthesized Povarov-Doebner type multicomponent reaction
Published in RSC medicinal chemistry (22-06-2023)“…The cGAS-STING axis plays an important role in protecting higher organisms against invading pathogens or cancer by promoting the production of cytokines and…”
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