Search Results - "Ong, Voon"

Using Autoantibodies and Cutaneous Subset to Develop Outcome‐Based Disease Classification in Systemic Sclerosis by Nihtyanova, Svetlana I., Sari, Alper, Harvey, Jennifer C., Leslie, Anna, Derrett‐Smith, Emma C., Fonseca, Carmen, Ong, Voon H., Denton, Christopher P.

“…Objective To describe the associations between autoantibodies, clinical presentation, and outcomes among patients with systemic sclerosis (SSc) in order to…”
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Association of anti-RNA polymerase III autoantibodies and cancer in scleroderma by Moinzadeh, Pia, Fonseca, Carmen, Hellmich, Martin, Shah, Ami A, Chighizola, Cecilia, Denton, Christopher P, Ong, Voon H

“…We assessed the profile and frequency of malignancy subtypes in a large single-centre UK cohort for patients with scleroderma (systemic sclerosis; SSc). We…”
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Renal Disease and Systemic Sclerosis: an Update on Scleroderma Renal Crisis by Cole, Alice, Ong, Voon H., Denton, Christopher P.

“…Scleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc) with a mortality of 20% at 6 months. Once the leading cause of…”
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Prediction of Pulmonary Complications and Long‐Term Survival in Systemic Sclerosis by Nihtyanova, Svetlana I., Schreiber, Benjamin E., Ong, Voon H., Rosenberg, Daniel, Moinzadeh, Pia, Coghlan, J. Gerrard, Wells, Athol U., Denton, Christopher P.

“…Objective To assess survival and incidence of organ‐based complications in a large single‐center cohort of unselected systemic sclerosis (SSc) patients, and to…”
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Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis by Khan, Korsa, Xu, Shiwen, Nihtyanova, Svetlana, Derrett-Smith, Emma, Abraham, David, Denton, Christopher P, Ong, Voon H

“…To determine the potential clinical and pathological significance of altered expression of interleukin 6 (IL-6) in systemic sclerosis (SSc). Serum IL-6 and…”
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Three Cases of Systemic Sclerosis Within One Family With Different Antibodies and Clinical Features by Spierings, Julia, Ong, Voon H, Denton, Christopher P

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The European Scleroderma Trials and Research group (EUSTAR) task force for the development of revised activity criteria for systemic sclerosis: derivation and validation of a preliminarily revised EUSTAR activity index by Valentini, Gabriele, Iudici, Michele, Walker, Ulrich A, Jaeger, Veronika K, Baron, Murray, Carreira, Patricia, Czirják, László, Denton, Christopher P, Distler, Oliver, Hachulla, Eric, Herrick, Ariane L, Kowal-Bielecka, Otylia, Pope, Janet, Müller-Ladner, Ulf, Riemekasten, Gabriela, Avouac, Jerome, Frerix, Marc, Jordan, Suzana, Minier, Tünde, Siegert, Elise, Ong, Voon H, Vettori, Serena, Allanore, Yannick

“…Validity of European Scleroderma Study Group (EScSG) activity indexes currently used to assess disease activity in systemic sclerosis (SSc) has been…”
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Dynamic Prediction of Pulmonary Hypertension in Systemic Sclerosis Using Landmark Analysis by Nihtyanova, Svetlana I., Schreiber, Benjamin E., Ong, Voon H., Wells, Athol U., Coghlan, John G., Denton, Christopher P.

“…Objective Pulmonary hypertension (PH) is a serious complication of systemic sclerosis (SSc). In this study, we explored the prediction of short‐term risk for…”
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The Use of Cyclosporine A in Rheumatology: a 2016 Comprehensive Review by Chighizola, Cecilia Beatrice, Ong, Voon H., Meroni, Pier Luigi

“…Cyclosporine A, an inhibitor of calcineurin, exerts an immunomodulator action interfering with T cell activation. Even though novel therapeutic tools have…”
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Consensus best practice pathway of the UK Scleroderma Study Group: digital vasculopathy in systemic sclerosis by Hughes, Michael, Ong, Voon H, Anderson, Marina E, Hall, Frances, Moinzadeh, Pia, Griffiths, Bridget, Baildam, Eileen, Denton, Christopher P, Herrick, Ariane L

“…Digital vasculopathy (comprising RP, digital ulceration and critical digital ischaemia) is responsible for much of the pain and disability experienced by…”
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A Phenome-Wide Association Study of Drugs and Comorbidities Associated With Gastrointestinal Dysfunction in Systemic Sclerosis by Maclean, Rory H, Ahmed, Fiza, Ong, Voon H, Murray, Charles D, Denton, Christopher P

“…To explore the causes of and contributors to gastrointestinal (GI) dysfunction in systemic sclerosis (SSc) in a phenome-wide association study (PheWAS), using…”
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Molecular basis for clinical diversity between autoantibody subsets in diffuse cutaneous systemic sclerosis by Clark, Kristina Elizabeth Neergaard, Campochiaro, Corrado, Csomor, Eszter, Taylor, Adam, Nevin, Katherine, Galwey, Nicholas, Morse, Mary A, Singh, Jennifer, Teo, Yee Voan, Ong, Voon H, Derrett-Smith, Emma, Wisniacki, Nicolas, Flint, Shaun M, Denton, Christopher P

“…Clinical heterogeneity is a cardinal feature of systemic sclerosis (SSc). Hallmark SSc autoantibodies are central to diagnosis and associate with distinct…”
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Combinations of scleroderma hallmark autoantibodies associate with distinct clinical phenotypes by Clark, Kristina E. N., Campochiaro, Corrado, Host, Lauren V., Sari, Alper, Harvey, Jennifer, Denton, Christopher P., Ong, Voon H.

“…Systemic sclerosis (SSc) is characterized by the presence of SSc-specific or SSc-associated antibodies (SSc-Abs): anti-topoisomerase I (ATA), anti-centromere…”
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Sustained benefit from intravenous immunoglobulin therapy for gastrointestinal involvement in systemic sclerosis by Raja, Jasmin, Nihtyanova, Svetlana I, Murray, Charles D, Denton, Christopher P, Ong, Voon H

“…IVIG is known to confer significant benefit in rheumatologic conditions, including inflammatory myopathy. This study aimed to assess the efficacy of IVIG…”
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BSR and BHPR guideline for the treatment of systemic sclerosis by Denton, Christopher P, Hughes, Michael, Gak, Nataliya, Vila, Josephine, Buch, Maya H, Chakravarty, Kuntal, Fligelstone, Kim, Gompels, Luke L, Griffiths, Bridget, Herrick, Ariane L, Pang, Jay, Parker, Louise, Redmond, Anthony, van Laar, Jacob, Warburton, Louise, Ong, Voon H

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Diffuse cutaneous systemic sclerosis following SARS-Co V-2 vaccination by Cole, Alice, Thomas, Rhys, Goldman, Nina, Howell, Kevin, Chakravarty, Kuntal, Denton, Christopher P., Ong, Voon H.

“…The largest world-wide vaccination rollout ever is currently underway to tackle the covid-19 pandemic. We report a case of diffuse cutaneous systemic sclerosis…”
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Zibotentan in systemic sclerosis-associated chronic kidney disease: a phase II randomised placebo-controlled trial by Stern, Edward P, Host, Lauren V, Wanjiku, Ivy, Escott, K Jane, Gilmour, Peter S, Ochiel, Rachel, Unwin, Robert, Burns, Aine, Ong, Voon H, Cadiou, Helen, O'Keeffe, Aidan G, Denton, Christopher P

“…We report results from a phase II randomised placebo-controlled trial assessing zibotentan, a highly selective endothelin receptor antagonist (ERA), in chronic…”
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Real-world experience of tocilizumab in systemic sclerosis: potential benefit on lung function for anti-topoisomerase-positive patients by Suleman, Yasir, Clark, Kristina E N, Cole, Alice R, Ong, Voon H, Denton, Christopher P

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Absence of Clinically Meaningful Drug-Drug Interactions with Rezafungin: Outcome of Investigations by Flanagan, Shawn, Walker, Helen, Ong, Voon, Sandison, Taylor

“…Rezafungin is a novel once-weekly echinocandin for intravenous injection currently in development for the treatment of infections and the prevention of ,…”
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The Yin and Yang of IL-17 in Systemic Sclerosis by Wei, Lanxuan, Abraham, David, Ong, Voon

“…IL-17 (IL-17A) is a pro-inflammatory cytokine produced by a sub-set of T helper cells termed Th17 cells primarily in response to cytokines like TGF-β and IL-23…”
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