Search Results - "Ong, Rick T.H"

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    Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations by Teo, Yik-Ying, Sim, Xueling, Ong, Rick T H, Tan, Adrian K S, Chen, Jieming, Tantoso, Erwin, Small, Kerrin S, Ku, Chee-Seng, Lee, Edmund J D, Seielstad, Mark, Chia, Kee-Seng

    Published in Genome research (01-11-2009)
    “…The Singapore Genome Variation Project (SGVP) provides a publicly available resource of 1.6 million single nucleotide polymorphisms (SNPs) genotyped in 268…”
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    Genomic copy number variations in three Southeast Asian populations by Ku, Chee-Seng, Pawitan, Yudi, Sim, Xueling, Ong, Rick T.H, Seielstad, Mark, Lee, Edmund J.D, Teo, Yik-Ying, Chia, Kee-Seng, Salim, Agus

    Published in Human mutation (01-07-2010)
    “…Research on the role of copy number variations (CNVs) in the genetic risk of diseases in Asian populations has been hampered by a relative lack of reference…”
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    A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis by Padyukov, Leonid, Seielstad, Mark, Ong, Rick T H, Ding, Bo, Rönnelid, Johan, Seddighzadeh, Maria, Alfredsson, Lars, Klareskog, Lars

    Published in Annals of the rheumatic diseases (01-02-2011)
    “…Rheumatoid arthritis (RA) can be divided into two major subsets based on the presence or absence of antibodies to citrullinated peptide antigens (ACPA). Until…”
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    A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region by Png, Eileen, Thalamuthu, Anbupalam, Ong, Rick T.H., Snippe, Harm, Boland, Greet J., Seielstad, Mark

    Published in Human molecular genetics (01-10-2011)
    “…We performed a two-stage genome-wide association study (GWAS) of antibody titer in 3614 hepatitis B vaccine recipients from Indonesia's Riau Archipelago,…”
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    Whole genome sequencing analysis of multidrug-resistant tuberculosis in Singapore, 2006–2018 by Chee, Cynthia B. E., Lim, Leo K. Y., Ong, Rick T. H., Sng, Li Hwei, Hsu, Li Yang, Lee, Vernon J. M., Wang, Yee Tang

    “…There were 290 multidrug-resistant (MDR)-TB cases diagnosed in Singapore from 2006 to 2018. Eighty-one percent were foreign-born. Spoligotyping and MIRU-VNTR…”
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    Natural positive selection and north-south genetic diversity in East Asia by CHENSUO, HAIYANXU, JIANJUN LIU, TAI, E-Shyong, WONG, Tien-Yin, CHIA, Kee-Seng, TEO, Yik-Ying, KHOR, Chiea-Chuen, TH ONG, Rick, SIM, Xueling, JIEMING CHEN, TAY, Wan-Ting, SIM, Kar-Seng, ZENG, Yi-Xin, XUEJUN ZHANG

    Published in European journal of human genetics : EJHG (01-01-2012)
    “…Recent reports have identified a north-south cline in genetic variation in East and South-East Asia, but these studies have not formally explored the basis of…”
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    Identifying candidate causal variants via trans-population fine-mapping by Teo, Yik-Ying, Ong, Rick T.H., Sim, Xueling, Tai, E-Shyong, Chia, Kee-Seng

    Published in Genetic epidemiology (01-11-2010)
    “…Genome‐wide association studies have discovered and confirmed a large number of loci that are implicated with disease susceptibility and severity…”
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    Association of Skin Barrier Genes within the PSORS4 Locus Is Enriched in Singaporean Chinese with Early-Onset Psoriasis by Chen, Huijia, Toh, Terry K.L., Szeverenyi, Ildiko, Ong, Rick T.H., Theng, Colin T.S., Irwin McLean, W.H., Seielstad, Mark, Birgitte Lane, E.

    Published in Journal of investigative dermatology (01-03-2009)
    “…Psoriasis (OMIM#177900) is a common polygenic skin disorder affecting approximately 2% of the northern European population and 0.1% of the Han Chinese…”
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