Search Results - "Ong, Rick T.H"
-
1
TRAF1–C5 as a Risk Locus for Rheumatoid Arthritis — A Genomewide Study
Published in The New England journal of medicine (20-09-2007)“…A genomewide association study of North American and Swedish patients with rheumatoid arthritis who were seropositive for autoantibodies against cyclic…”
Get full text
Journal Article -
2
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations
Published in Genome research (01-11-2009)“…The Singapore Genome Variation Project (SGVP) provides a publicly available resource of 1.6 million single nucleotide polymorphisms (SNPs) genotyped in 268…”
Get full text
Journal Article -
3
Genomic copy number variations in three Southeast Asian populations
Published in Human mutation (01-07-2010)“…Research on the role of copy number variations (CNVs) in the genetic risk of diseases in Asian populations has been hampered by a relative lack of reference…”
Get full text
Journal Article -
4
Analysis of 39 Crohn's disease risk loci in Swedish inflammatory bowel disease patients
Published in Inflammatory bowel diseases (01-06-2010)Get full text
Journal Article -
5
Meta-analysis identifies common variants associated with body mass index in east Asians
Published in Nature genetics (01-03-2012)“…Xiao-Ou Shu and colleagues report a meta-analysis of genome-wide association studies for body mass index (BMI) in east Asians. They identify three new genetic…”
Get full text
Journal Article -
6
Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations
Published in Human molecular genetics (20-12-2014)“…Previous studies have emphasized ethnically heterogeneous human leukocyte antigen (HLA) classical allele associations to rheumatoid arthritis (RA) risk. We…”
Get full text
Journal Article -
7
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
Published in Nature genetics (01-04-2010)“…Mark Seielstad and colleagues report results of a large genome-wide association and replication study of ulcerative colitis. The work identifies several new…”
Get full text
Journal Article -
8
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis
Published in Annals of the rheumatic diseases (01-02-2011)“…Rheumatoid arthritis (RA) can be divided into two major subsets based on the presence or absence of antibodies to citrullinated peptide antigens (ACPA). Until…”
Get more information
Journal Article -
9
A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region
Published in Human molecular genetics (01-10-2011)“…We performed a two-stage genome-wide association study (GWAS) of antibody titer in 3614 hepatitis B vaccine recipients from Indonesia's Riau Archipelago,…”
Get full text
Journal Article -
10
Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1
Published in Nature genetics (01-11-2011)“…Hypovolemic shock (dengue shock syndrome (DSS)) is the most common life-threatening complication of dengue. We conducted a genome-wide association study of…”
Get full text
Journal Article -
11
Whole genome sequencing analysis of multidrug-resistant tuberculosis in Singapore, 2006–2018
Published in European journal of clinical microbiology & infectious diseases (01-05-2021)“…There were 290 multidrug-resistant (MDR)-TB cases diagnosed in Singapore from 2006 to 2018. Eighty-one percent were foreign-born. Spoligotyping and MIRU-VNTR…”
Get full text
Journal Article -
12
Natural positive selection and north-south genetic diversity in East Asia
Published in European journal of human genetics : EJHG (01-01-2012)“…Recent reports have identified a north-south cline in genetic variation in East and South-East Asia, but these studies have not formally explored the basis of…”
Get full text
Journal Article -
13
Identifying candidate causal variants via trans-population fine-mapping
Published in Genetic epidemiology (01-11-2010)“…Genome‐wide association studies have discovered and confirmed a large number of loci that are implicated with disease susceptibility and severity…”
Get full text
Journal Article -
14
Association of Skin Barrier Genes within the PSORS4 Locus Is Enriched in Singaporean Chinese with Early-Onset Psoriasis
Published in Journal of investigative dermatology (01-03-2009)“…Psoriasis (OMIM#177900) is a common polygenic skin disorder affecting approximately 2% of the northern European population and 0.1% of the Han Chinese…”
Get full text
Journal Article -
15
Erratum: Genome-wide association identifies multiple ulcerative colitis susceptibility loci
Published in Nature genetics (01-04-2011)“…Nat. Genet. 42, 332–337 (2010); published online 14 March 2010; corrected after print 29 March 2011 In the version of this article initially published, Kathryn…”
Get full text
Journal Article