Search Results - "Ong, David"

Benzodiazepine-associated delirium in critically ill adults by Zaal, Irene J., Devlin, John W., Hazelbag, Marijn, Klein Klouwenberg, Peter M. C., van der Kooi, Arendina W., Ong, David S. Y., Cremer, Olaf L., Groenwold, Rolf H., Slooter, Arjen J. C.

“…Purpose The association between benzodiazepine use and delirium risk in the ICU remains unclear. Prior investigations have failed to account for disease…”
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How to interpret and use COVID-19 serology and immunology tests by Ong, David S.Y., Fragkou, Paraskevi C., Schweitzer, Valentijn A., Chemaly, Roy F., Moschopoulos, Charalampos D., Skevaki, Chrysanthi

“…Although molecular tests are considered the reference standard for coronavirus disease 2019 (COVID-19) diagnostics, serological and immunological tests may be…”
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Likelihood of infection in patients with presumed sepsis at the time of intensive care unit admission: a cohort study by Klein Klouwenberg, Peter M C, Cremer, Olaf L, van Vught, Lonneke A, Ong, David S Y, Frencken, Jos F, Schultz, Marcus J, Bonten, Marc J, van der Poll, Tom

“…A clinical suspicion of infection is mandatory for diagnosing sepsis in patients with a systemic inflammatory response syndrome. Yet, the accuracy of…”
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Outbreak of Coronavirus Disease 2019 (COVID-19) in a Nursing Home Associated With Aerosol Transmission as a Result of Inadequate Ventilation by de Man, Peter, Paltansing, Sunita, Ong, David S Y, Vaessen, Norbert, van Nielen, Gerard, Koeleman, Johannes G M

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Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome by Ong, David S. Y., Spitoni, Cristian, Klein Klouwenberg, Peter M. C., Verduyn Lunel, Frans M., Frencken, Jos F., Schultz, Marcus J., van der Poll, Tom, Kesecioglu, Jozef, Bonten, Marc J. M., Cremer, Olaf L.

“…Purpose Cytomegalovirus (CMV) reactivation occurs frequently in patients with the acute respiratory distress syndrome (ARDS) and has been associated with…”
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Electronic Implementation of a Novel Surveillance Paradigm for Ventilator-associated Events: Feasibility and Validation by KLEIN KLOUWENBERG, Peter M. C, VAN MOURIK, Maaike S. M, ONG, David S. Y, HORN, Janneke, SCHULTZ, Marcus J, CREMER, Olaf L, BONTEN, Marc J. M

“…Accurate surveillance of ventilator-associated pneumonia (VAP) is hampered by subjective diagnostic criteria. A novel surveillance paradigm for…”
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Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients by Claushuis, Theodora A.M., van Vught, Lonneke A., Scicluna, Brendon P., Wiewel, Maryse A., Klein Klouwenberg, Peter M.C., Hoogendijk, Arie J., Ong, David S.Y., Cremer, Olaf L., Horn, Janneke, Franitza, Marek, Toliat, Mohammad R., Nürnberg, Peter, Zwinderman, Aeilko H., Bonten, Marc J., Schultz, Marcus J., van der Poll, Tom

“…Preclinical studies have suggested that platelets influence the host response during sepsis. We sought to assess the association of admission thrombocytopenia…”
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Biological Subphenotypes of Acute Respiratory Distress Syndrome Show Prognostic Enrichment in Mechanically Ventilated Patients without Acute Respiratory Distress Syndrome by Heijnen, Nanon F. L., Hagens, Laura A., Smit, Marry R., Cremer, Olaf L., Ong, David S. Y., van der Poll, Tom, van Vught, Lonneke A., Scicluna, Brendon P., Schnabel, Ronny M., van der Horst, Iwan C. C., Schultz, Marcus J., Bergmans, Dennis C. J. J., Bos, Lieuwe D. J., de Beer, Friso M., Bos, Lieuwe D., Glas, Gerie J., Horn, Janneke, Hoogendijk, Arie J., van Hooijdonk, Roosmarijn T., Huson, Mischa A., van der Poll, Tom, Scicluna, Brendon, Schouten, Laura R., Schultz, Marcus J., Straat, Marleen, van Vught, Lonneke A., Wieske, Luuk, Wievel, Maryse A., Witteveen, Esther, Bonten, Marc J., Cremer, Olaf L., Frencken, Jos F., van de Groep, Kirsten, Klein Klouwenberg, Peter M., Koster-Brouwer, Maria E., Ong, David S., Varkila, Meri R., Verboom, Diana M.

“…Heijnen et al discuss their study which aim to determine whether these subphenotypes and their prognostic and potential for predictive enrichment could be…”
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Classification of sepsis, severe sepsis and septic shock: the impact of minor variations in data capture and definition of SIRS criteria by Klein Klouwenberg, Peter M. C., Ong, David S. Y., Bonten, Marc J. M., Cremer, Olaf L.

“…Purpose To quantify the effects of minor variations in the definition and measurement of systemic inflammatory response syndrome (SIRS) criteria and organ…”
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Human bocavirus in stool: A true pathogen or an innocent bystander? by Ong, David S.Y, Schuurman, Rob, Heikens, Esther

“…Highlights • The prevalence of human bocavirus (HBoV) in stool is similar between patients with gastro-intestinal symptoms and healthy controls. • Other…”
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Incidence, Predictors, and Outcomes of New-Onset Atrial Fibrillation in Critically Ill Patients with Sepsis. A Cohort Study by Klein Klouwenberg, Peter M C, Frencken, Jos F, Kuipers, Sanne, Ong, David S Y, Peelen, Linda M, van Vught, Lonneke A, Schultz, Marcus J, van der Poll, Tom, Bonten, Marc J, Cremer, Olaf L

“…Patients admitted to intensive care units with sepsis are prone to developing cardiac dysrhythmias, most commonly atrial fibrillation. To determine the…”
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A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission by Scicluna, Brendon P, Klein Klouwenberg, Peter M C, van Vught, Lonneke A, Wiewel, Maryse A, Ong, David S Y, Zwinderman, Aeilko H, Franitza, Marek, Toliat, Mohammad R, Nürnberg, Peter, Hoogendijk, Arie J, Horn, Janneke, Cremer, Olaf L, Schultz, Marcus J, Bonten, Marc J, van der Poll, Tom

“…Community-acquired pneumonia (CAP) accounts for a major proportion of intensive care unit (ICU) admissions for respiratory failure and sepsis. Diagnostic…”
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SARS-CoV-2 antibody and T cell responses one year after COVID-19 and the booster effect of vaccination: A prospective cohort study by Mak, Willem A., Koeleman, Johannes G.M., van der Vliet, Marijke, Keuren, Frans, Ong, David S.Y.

“…•SARS-CoV-2-specific T cell and IgG responses persist for up to one year post COVID-19.•Immune responses increased after first but not second vaccination in…”
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Understanding Heterogeneity in Biologic Phenotypes of Acute Respiratory Distress Syndrome by Leukocyte Expression Profiles by Bos, Lieuwe D J, Scicluna, Brendon P, Ong, David S Y, Cremer, Olaf, van der Poll, Tom, Schultz, Marcus J

“…Two biologic phenotypes of acute respiratory distress syndrome (ARDS) have been identified based on plasma protein markers in four previous studies. To…”
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Ectopic gut colonization: a metagenomic study of the oral and gut microbiome in Crohn's disease by Hu, Shijia, Png, Eileen, Gowans, Michelle, Ong, David E H, de Sessions, Paola Florez, Song, Jie, Nagarajan, Niranjan

“…This study aims to characterize, the gut and oral microbiome in Asian subjects with Crohn's disease (CD) using whole genome shotgun sequencing, thereby…”
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Clinical evaluation of rapid point-of-care antigen tests for diagnosis of SARS-CoV-2 infection by Koeleman, Johannes G. M., Brand, Henk, de Man, Stijn J., Ong, David S. Y.

“…The RT-qPCR in respiratory specimens is the gold standard for diagnosing acute COVID-19 infections. However, this test takes considerable time before test…”
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Short-Course Adjunctive Gentamicin as Empirical Therapy in Patients With Severe Sepsis and Septic Shock: A Prospective Observational Cohort Study by Ong, David S. Y., Frencken, Jos F., Klouwenberg, Peter M. C. Klein, Juffermans, Nicole, van der Poll, Tom, Bonten, Marc J. M., Cremer, Olaf L.

“…Background. Metaanalyses failed to demonstrate clinical benefits of beta lactam plus aminoglycoside combination therapy compared to beta lactam monotherapy in…”
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Rapid screening method for the detection of SARS-CoV-2 variants of concern by Ong, David S.Y., Koeleman, Johannes G.M., Vaessen, Norbert, Breijer, Simone, Paltansing, Sunita, de Man, Peter

“…•Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC) are characterized by their increased transmissibility, immune evasion…”
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World Antibiotic Awareness Week and European Antibiotic Awareness Day, November 2018: An analysis of the impact of Twitter activity by Mackenzie, Douglas Graham, Ong, David S Y, Ashiru-Oredope, Diane

“…•World Antibiotic Awareness Week 2018 had huge social media activity (14 400 tweets)•The official campaign hashtag #AntibioticResistance did not help…”
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Epidemiology of Multiple Herpes Viremia in Previously Immunocompetent Patients With Septic Shock by Ong, David S. Y., Bonten, Marc J. M., Spitoni, Cristian, Lunel, Frans M. Verduyn, Frencken, Jos F., Horn, Janneke, Schultz, Marcus J., van der Poll, Tom, Klouwenberg, Peter M. C. Klein, Cremer, Olaf L.

“…Background. Systemic reactivations of herpesviruses may occur in intensive care unit (ICU) patients, even in those without prior immune deficiency. However,…”
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