Search Results - "Ong, Clara Chong Hui"
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High Densities of Tumor-Associated Plasma Cells Predict Improved Prognosis in Triple Negative Breast Cancer
Published in Frontiers in immunology (30-05-2018)“…Breast cancer is the most common malignancy affecting women, but the heterogeneity of the condition is a significant obstacle to effective treatment. Triple…”
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Hypoxia-regulated carbonic anhydrase IX (CAIX) protein is an independent prognostic indicator in triple negative breast cancer
Published in Breast cancer research : BCR (03-06-2022)“…The effect of extracellular microenvironment (hypoxia and pH) has been regarded as a key hallmark in cancer progression. The study aims to investigate the…”
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Tertiary lymphoid structures and associated plasma cells play an important role in the biology of triple-negative breast cancers
Published in Breast cancer research and treatment (01-04-2020)“…Purpose Triple-negative breast cancers (TNBC) are aggressive tumours that exhibit abundant lymphoid infiltrates which modulate tumour behaviour. Recent…”
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SRSF1 mediates cytokine-induced impaired imatinib sensitivity in chronic myeloid leukemia
Published in Leukemia (01-07-2020)“…Patients with chronic myeloid leukemia (CML) who are treated with tyrosine kinase inhibitors (TKIs) experience significant heterogeneity regarding depth and…”
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Expression of CD38 on Macrophages Predicts Improved Prognosis in Hepatocellular Carcinoma
Published in Frontiers in immunology (04-09-2019)“…CD38 is involved in the adenosine pathway, which represents one of the immunosuppressive mechanisms in cancer. CD38 is broadly expressed across immune cell…”
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Evaluation of phospho-histone H3 in Asian triple-negative breast cancer using multiplex immunofluorescence
Published in Breast cancer research and treatment (01-11-2019)“…Purpose We used multiplex immunofluorescence (mIF) to determine whether mitotic rate represents an independent prognostic marker in triple-negative breast…”
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Characteristics, behaviour and role of biomarkers in metastatic triple-negative breast cancer
Published in Journal of clinical pathology (01-03-2020)“…Characterising the factors responsible for metastatic triple-negative breast cancer (TNBC) is of significant importance, considering its high mortality rate…”
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Prognostic value of CD8 + PD-1+ immune infiltrates and PDCD1 gene expression in triple negative breast cancer
Published in Journal for immunotherapy of cancer (06-02-2019)“…The role of programmed cell death protein-1 (PD-1)/programmed cell death ligand 1 (PD-L1) in triple negative breast cancer (TNBC) remains to be fully…”
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Viable mpox virus in the environment of a patient room
Published in International journal of infectious diseases (01-06-2023)“…•Environmental swab and dust sampling showed extensive surface contamination of the hospital room by mpox virus (MPXV).•MPXV DNA was consistently detected in…”
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The role of Ki-67 in Asian triple negative breast cancers: a novel combinatory panel approach
Published in Virchows Archiv : an international journal of pathology (01-12-2019)“…The proliferation marker Ki-67 is frequently used to assess aggressiveness in the pathological evaluation of cancer, but its role remains uncertain in…”
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Nosocomial infections among COVID-19 patients: an analysis of intensive care unit surveillance data
Published in Antimicrobial resistance & infection control (12-08-2021)“…Surveillance of nosocomial infections, like catheter-associated urinary tract infection (CAUTI), central line-associated bloodstream infection, possible…”
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SG-APSIC1099: Scoping review of cleaning of high-touch surfaces (HTSs) in inpatient wards
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (01-02-2023)“…Objectives: High-touch surface (HTS) cleaning is critical to prevent healthcare-associated infections. However, HTS definitions and cleaning frequency vary…”
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SG-APSIC1123: Diagnostic and infection prevention and control (IPC) performance of rapid polymerase chain reaction (PCR) compared to conventional culture PCR methods for detecting carbapenemase-producing organisms (CPOs)
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (01-02-2023)“…Objectives: In this study, we compared the performance of a rapid polymerase chain reaction (PCR) method in detecting carbapenemase-producing organisms (CPOs)…”
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SG-APSIC1091: Assessment of compliance to cleaning of computers by healthcare workers (HCWs) using adenosine triphosphate (ATP) measurement
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (01-02-2023)“…Objectives: HCWs are recommended to wipe the computers with alcohol wipes before clinical use. Compliance assessment by direct observation is resource…”
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SG-APSIC1122: Observational study of handwashing sink activities in the inpatient setting
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (01-02-2023)“…Objectives: The use of handwashing sinks for activities other than hand hygiene (HH) is associated with higher rates of β-lactamase–producing…”
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SG-APSIC1118: Introduction of carbapenemase-producing Enterobacterales (CPE) in the aqueous environment of the newly built National Centre for Infectious Diseases (NCID) in Singapore
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (01-02-2023)“…Objectives: In healthcare facilities, environmental reservoirs of CPE are associated with CPE outbreaks. In the newly built NCID building, we studied the…”
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SG-APSIC1095: Acquisition rate of carbapenemase-producing organisms (CPOs) among hospital contacts of CPO patients: An interim subgroup analysis of a cohort study
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (01-02-2023)“…Objectives: The increase in carbapenemase-producing organism (CPO) transmission among hospitalized patients is a growing concern. Studies investigating the…”
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SG-APSIC1097: The impact of COVID-19 on the incidence of carbapenem-resistant Enterobacterales (CRE) in Singapore: An interrupted time-series analysis
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (01-02-2023)“…Objectives: Over the past 2 years, many infection prevention and control (IPC) resources have been diverted to manage the COVID-19 pandemic. Its impact on the…”
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An automated staining protocol for seven-colour immunofluorescence of human tissue sections for diagnostic and prognostic use
Published in Pathology (01-04-2018)“…Multiplex immunofluorescence (mIF) allows simultaneous antibody-based detection and quantification of the expression of up to six markers, plus a nuclear…”
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Compliance with face mask use during the COVID-19 pandemic: a community observational study in Singapore
Published in Singapore medical journal (27-04-2023)Get full text
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