Search Results - "Ong, Boon‐Hean"

Revisiting neoadjuvant therapy in non-small-cell lung cancer by Saw, Stephanie P L, Ong, Boon-Hean, Chua, Kevin L M, Takano, Angela, Tan, Daniel S W

“…Despite the rapidly evolving treatment landscape in advanced non-small-cell lung cancer (NSCLC), developments in neoadjuvant and adjuvant treatments have been…”
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Genomic landscape of lung adenocarcinoma in East Asians by Chen, Jianbin, Yang, Hechuan, Teo, Audrey Su Min, Amer, Lidyana Bte, Sherbaf, Faranak Ghazi, Tan, Chu Quan, Alvarez, Jacob Josiah Santiago, Lu, Bingxin, Lim, Jia Qi, Takano, Angela, Nahar, Rahul, Lee, Yin Yeng, Phua, Cheryl Zi Jin, Chua, Khi Pin, Suteja, Lisda, Chen, Pauline Jieqi, Chang, Mei Mei, Koh, Tina Puay Theng, Ong, Boon-Hean, Anantham, Devanand, Hsu, Anne Ann Ling, Gogna, Apoorva, Too, Chow Wei, Aung, Zaw Win, Lee, Yi Fei, Wang, Lanying, Lim, Tony Kiat Hon, Wilm, Andreas, Choi, Poh Sum, Ng, Poh Yong, Toh, Chee Keong, Lim, Wan-Teck, Ma, Siming, Lim, Bing, Liu, Jin, Tam, Wai Leong, Skanderup, Anders Jacobsen, Yeong, Joe Poh Sheng, Tan, Eng-Huat, Creasy, Caretha L., Tan, Daniel Shao Weng, Hillmer, Axel M., Zhai, Weiwei

“…Lung cancer is the world’s leading cause of cancer death and shows strong ancestry disparities. By sequencing and assembling a large genomic and transcriptomic…”
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Detection of circulating tumor DNA with ultradeep sequencing of plasma cell‐free DNA for monitoring minimal residual disease and early detection of recurrence in early‐stage lung cancer by Tan, Aaron C., Lai, Gillianne G. Y., Saw, Stephanie P. L., Chua, Kevin L. M., Takano, Angela, Ong, Boon‐Hean, Koh, Tina P. T., Jain, Amit, Tan, Wan Ling, Ng, Quan Sing, Kanesvaran, Ravindran, Rajasekaran, Tanujaa, Kalashnikova, Ekaterina, Renner, Derrick, Sudhaman, Sumedha, Malhotra, Meenakshi, Sethi, Himanshu, Liu, Minetta C., Aleshin, Alexey, Lim, Wan‐Teck, Tan, Eng‐Huat, Skanderup, Anders J., Ang, Mei‐Kim, Tan, Daniel S. W.

“…Background In early‐stage non–small cell lung cancer (NSCLC), recurrence is frequently observed. Circulating tumor DNA (ctDNA) has emerged as a noninvasive…”
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Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and cost-effectiveness analysis by Tan, Aaron C., Lai, Gillianne G.Y., Tan, Gek San, Poon, Shou Yu, Doble, Brett, Lim, Tse Hui, Aung, Zaw Win, Takano, Angela, Tan, Wan Ling, Ang, Mei-Kim, Tan, Bien Soo, Devanand, Anantham, Too, Chow Wei, Gogna, Apoorva, Ong, Boon-Hean, Koh, Tina P.T., Kanesvaran, Ravindran, Ng, Quan Sing, Jain, Amit, Rajasekaran, Tanujaa, Lim, Alvin S.T., Lim, Wan Teck, Toh, Chee Keong, Tan, Eng-Huat, Lim, Tony Kiat Hon, Tan, Daniel S.W.

“…•Upfront NGS is feasible and cost-effective in an EGFR mutant predominant population.•Characterizing the wider genomic profile may yield important…”
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Molecular testing in stage I–III non-small cell lung cancer: Approaches and challenges by Aggarwal, Charu, Bubendorf, Lukas, Cooper, Wendy A., Illei, Peter, Borralho Nunes, Paula, Ong, Boon-Hean, Tsao, Ming-Sound, Yatabe, Yasushi, Kerr, Keith M.

“…•Routine molecular testing in stage I–III NSCLC has not been required to date.•However, targeted agents are undergoing trials in adjuvant and neoadjuvant…”
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Hybrid operating room with ceiling mounted imaging system assisted pre-operative and intra-operative lung nodule localization for thoracoscopic resections: a 5-year case series by Chia, Audrey Qi Xin, Gogna, Apoorva, Pena, Angela Maria Takano, Sai, Vishnu Vemula Sri, Chandramohan, Sivanathan, Chan, Shaun Ju Min Xavier, Ong, Boon-Hean

“…Video-assisted thoracoscopic (VATS) lung resections are increasingly popular and localization techniques are necessary to aid resection. We describe our…”
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Use of the extended pectoralis major myocutaneous flap as a wrap-around for mediastinal tracheal repair by Tan, Grace Hui-Min, Ong, Boon-Hean, Kok, Yee-Onn, Tan, Bien-Keem

“…Persistent tracheoesophageal fistulas requiring flap repair of the trachea in the mediastinum are uncommon. A 44-year-old man developed a 5 cm x 2 cm…”
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Association of Clinicopathologic and Molecular Tumor Features With Recurrence in Resected Early-Stage Epidermal Growth Factor Receptor-Positive Non-Small Cell Lung Cancer by Saw, Stephanie P L, Zhou, Siqin, Chen, Jianbin, Lai, Gillianne, Ang, Mei-Kim, Chua, Kevin, Kanesvaran, Ravindran, Ng, Quan Sing, Jain, Amit, Tan, Wan Ling, Rajasekaran, Tanujaa, Lim, Darren W T, Tan, Aaron, Fong, Kam Weng, Takano, Angela, Cheng, Xin Ming, Lim, Kiat Hon, Koh, Tina, Ong, Boon-Hean, Tan, Eng Huat, Toh, Chee Keong, Skanderup, Anders J, Tan, Sze Huey, Tan, Daniel S W

“…The recently published ADAURA study has posed a significant dilemma for clinicians in selecting patients for adjuvant osimertinib. Risk factors for recurrence…”
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Practical Considerations for Solid Organ Transplantation During the COVID-19 Global Outbreak: The Experience from Singapore by Chung, Shimin Jasmine, Tan, Ek Khoon, Kee, Terence, Krishnamoorthy, Thinesh Lee, Phua, Ghee Chee, Sewa, Duu Wen, Ong, Boon-Hean, Tan, Teing Ee, Sivathasan, Cumaraswamy, Gan, Huei Li Valerie, Goh, Brian Kim Poh, Jeyaraj, Prema Raj, Tan, Ban Hock

“…The current coronavirus disease 2019 (COVID-19) pandemic has not only caused global social disruptions but has also put tremendous strain on healthcare systems…”
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Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates by Simoni, Yannick, Becht, Etienne, Fehlings, Michael, Loh, Chiew Yee, Koo, Si-Lin, Teng, Karen Wei Weng, Yeong, Joe Poh Sheng, Nahar, Rahul, Zhang, Tong, Kared, Hassen, Duan, Kaibo, Ang, Nicholas, Poidinger, Michael, Lee, Yin Yeng, Larbi, Anis, Khng, Alexis J., Tan, Emile, Fu, Cherylin, Mathew, Ronnie, Teo, Melissa, Lim, Wan Teck, Toh, Chee Keong, Ong, Boon-Hean, Koh, Tina, Hillmer, Axel M., Takano, Angela, Lim, Tony Kiat Hon, Tan, Eng Huat, Zhai, Weiwei, Tan, Daniel S. W., Tan, Iain Beehuat, Newell, Evan W.

“…Various forms of immunotherapy, such as checkpoint blockade immunotherapy, are proving to be effective at restoring T cell-mediated immune responses that can…”
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IL-11 is a crucial determinant of cardiovascular fibrosis by Schafer, Sebastian, Viswanathan, Sivakumar, Widjaja, Anissa A., Lim, Wei-Wen, Moreno-Moral, Aida, DeLaughter, Daniel M., Ng, Benjamin, Patone, Giannino, Chow, Kingsley, Khin, Ester, Tan, Jessie, Chothani, Sonia P., Ye, Lei, Rackham, Owen J. L., Ko, Nicole S. J., Sahib, Norliza E., Pua, Chee Jian, Zhen, Nicole T. G., Xie, Chen, Wang, Mao, Maatz, Henrike, Lim, Shiqi, Saar, Kathrin, Blachut, Susanne, Petretto, Enrico, Schmidt, Sabine, Putoczki, Tracy, Guimarães-Camboa, Nuno, Wakimoto, Hiroko, van Heesch, Sebastiaan, Sigmundsson, Kristmundur, Lim, See L., Soon, Jia L., Chao, Victor T. T., Chua, Yeow L., Tan, Teing E., Evans, Sylvia M., Loh, Yee J., Jamal, Muhammad H., Ong, Kim K., Chua, Kim C., Ong, Boon-Hean, Chakaramakkil, Mathew J., Seidman, Jonathan G., Seidman, Christine E., Hubner, Norbert, Sin, Kenny Y. K., Cook, Stuart A.

“…Fibroblast-specific Il-11 expression causes heart and kidney fibrosis and organ failure, whereas IL-11 inhibition prevents fibroblast activation and organ…”
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Use of Indocyanine Green Fluorescence Imaging in Thoracic and Esophageal Surgery by Ng, Calvin Sze-Hang, Ong, Boon-Hean, Chao, Yin Kai, Wright, Gavin M., Sekine, Yasuo, Wong, Ian, Hao, Zhexue, Zhang, Guangjian, Chaturvedi, Harit, Thammineedi, Subramanyeshwar Rao, Law, Simon, Kim, Hyun Koo

“…Fluorescence imaging using indocyanine green in thoracic and esophageal surgery is gaining popularity because of the potential to facilitate surgical planning,…”
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Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer by Lai, Gillianne G Y, Lim, Tse Hui, Lim, John, Liew, Perry J R, Kwang, Xue Lin, Nahar, Rahul, Aung, Zaw Win, Takano, Angela, Lee, Yin Yeng, Lau, Dawn P X, Tan, Gek San, Tan, Sze Huey, Tan, Wan Ling, Ang, Mei-Kim, Toh, Chee Keong, Tan, Bien Soo, Devanand, Anantham, Too, Chow Wei, Gogna, Apoorva, Ong, Boon Hean, Koh, Tina P T, Kanesvaran, Ravindran, Ng, Quan Sing, Jain, Amit, Rajasekaran, Tanujaa, Yuan, Ju, Lim, Tony Kiat Hon, Lim, Alvin S T, Hillmer, Axel M, Lim, Wan Teck, Iyer, N Gopalakrishna, Tam, Wai Leong, Zhai, Weiwei, Tan, Eng-Huat, Tan, Daniel S W

“…Mesenchymal epithelial transition factor ( MET) activation has been implicated as an oncogenic driver in epidermal growth factor receptor ( EGFR)-mutant…”
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PD-L1 score as a prognostic biomarker in asian early-stage epidermal growth factor receptor-mutated lung cancer by Saw, Stephanie P.L., Ng, Win Pin, Zhou, Siqin, Lai, Gillianne G.Y., Tan, Aaron C., Ang, Mei-Kim, Lim, Wan-Teck, Kanesvaran, Ravindran, Ng, Quan Sing, Jain, Amit, Tan, Wan Ling, Rajasekaran, Tanujaa, Chan, Johan W.K., Teh, Yi Lin, Pang, Mengyuan, Yeo, Jia-Chi, Takano, Angela, Ong, Boon-Hean, Tan, Eng-Huat, Tan, Sze Huey, Skanderup, Anders J., Tan, Daniel S.W.

“…To determine the prognostic value of programmed death-ligand 1 (PD-L1) score in early-stage epidermal growth factor receptor (EGFR)-mutated non-small cell lung…”
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Migration of breast augmentation filler to the mediastinum mimicking lymphoma: A case report by Huang, Mingjie, Ong, Yee Siang, Ong, Boon-Hean

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Multidisciplinary lung cancer clinic: An emerging model of care by Saw, Stephanie Pei Li, Chua, Kevin Lee Min, Ong, Boon Hean, Lim, Darren Wan Teck, Lai, Gillianne Geet Yi, Tan, Daniel Shao Weng, Ang, Mei Kim

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Prognostic Factors for Survival After Extracorporeal Membrane Oxygenation for Cardiogenic Shock by Huang, Mingjie, Ong, Boon Hean, Hoo, Anne Ean Ean, Gao, Fei, Chao, Victor Tar Toong, Lim, Chong Hee, Tan, Teing Ee, Sin, Kenny Yoong Kong

“…The aim of this study is to examine factors that can predict mortality in patients that have veno-arterial extracorporeal membrane oxygenation (VA-ECMO)…”
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Post-implantation transcatheter aortic valve migration in a left ventricular assist device patient with severe aortic insufficiency by Ong, Boon-Hean, Chiam, Paul T L, Sim, David K L, Tan, Teing-Ee

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Abstract 5114: Ultra-sensitive detection of minimal residual disease (MRD) through whole genome sequencing (WGS) using an AI-based error suppression model in resected early-stage non-small cell lung cancer (NSCLC) by Tan, Aaron C., Saw, Stephanie P., Lai, Gillianne G., Chua, Kevin L., Takano, Angela, Ong, Boon-Hean, Koh, Tina P., Jain, Amit, Tan, Wan Ling, Ng, Quan Sing, Kanesvaran, Ravindran, Rajasekaran, Tanujaa, Deochand, Sunil, Maloney, Dillon, Afterman, Danielle, Lauterman, Tomer, Friedman, Noah, Bourzgui, Imane, Ramaraj, Nidhi, Donenhirsh, Zohar, Veksler, Ronel, Rosenfeld, Jonathan, Kandasamy, Ravi, Tavassoly, Iman, Oklander, Boris, Zviran, Asaf, Lim, Wan-Teck, Tan, Eng-Huat, Skanderup, Anders J., Ang, Mei-Kim, Tan, Daniel S.

“…Abstract Background: Early detection of recurrence and monitoring of MRD post-surgery is critical for clinical decision-making to tailor adjuvant therapy. In…”
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Two-stage operation for an extensive infected aortic arch by Nakao, Masakazu, MD, MRCS, Lim, Yeong Phang, MBBS, FRCS, FAMS, Jarmin, Martin John, MD, Ong, Boon Hean, MBBS, MRCS, Chua, Yeow Leng, MBBS, FRCS, FAMS

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