Search Results - "Ong, Albert"

A polycystin-centric view of cyst formation and disease: the polycystins revisited by Ong, Albert C M, Harris, Peter C

“…It is 20 years since the identification of PKD1, the major gene mutated in autosomal dominant polycystic kidney disease (ADPKD), followed closely by the…”
Get more information

Autosomal dominant polycystic kidney disease: the changing face of clinical management by Ong, Albert C M, Prof, Devuyst, Olivier, Prof, Knebelmann, Bertrand, Prof, Walz, Gerd, Prof

“…Summary Autosomal dominant polycystic kidney disease is the most common inherited kidney disease and accounts for 7–10% of all patients on renal replacement…”
Get full text

Fabrication of Luminescent Monolayered Tungsten Dichalcogenides Quantum Dots with Giant Spin-Valley Coupling by Lin, Liangxu, Xu, Yaoxian, Zhang, Shaowei, Ross, Ian M, Ong, Albert C. M, Allwood, Dan A

“…A high yield (>36 wt %) method has been developed of preparing monolayered tungsten dichalcogenide (WS2) quantum dots (QDs) with lateral size ∼8–15 nm from…”
Get full text

Fabrication and Luminescence of Monolayered Boron Nitride Quantum Dots by Lin, Liangxu, Xu, Yaoxian, Zhang, Shaowei, Ross, Ian M., Ong, Albert C. M., Allwood, Dan A.

“…Monolayered boron nitride (BN) quantum dots (QDs; lateral size ≈10 nm) are fabricated using a novel method. Unlike monolayered BN sheets, these BN QDs exhibit…”
Get full text

Liver transplant recipients with polycystic liver disease have longer waiting times but better long-term clinical outcomes than those with liver disease due to other causes: A retrospective cross-sectional study by Gittus, Matt, Moore, Joanna, Ong, Albert C M

“…Liver transplantation is the only curative option for patients with polycystic liver disease (PLD). In the United Kingdom, these patients are listed on the…”
Get full text

Chronic kidney disease and the global public health agenda: an international consensus by Francis, Anna, Harhay, Meera N., Ong, Albert C. M., Tummalapalli, Sri Lekha, Ortiz, Alberto, Fogo, Agnes B., Fliser, Danilo, Roy-Chaudhury, Prabir, Fontana, Monica, Nangaku, Masaomi, Wanner, Christoph, Malik, Charu, Hradsky, Anne, Adu, Dwomoa, Bavanandan, Sunita, Cusumano, Ana, Sola, Laura, Ulasi, Ifeoma, Jha, Vivekanand

“…Early detection is a key strategy to prevent kidney disease, its progression and related complications, but numerous studies show that awareness of kidney…”
Get full text

An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International by Müller, Roman-Ulrich, Messchendorp, A Lianne, Birn, Henrik, Capasso, Giovambattista, Cornec-Le Gall, Emilie, Devuyst, Olivier, van Eerde, Albertien, Guirchoun, Patrick, Harris, Tess, Hoorn, Ewout J, Knoers, Nine V A M, Korst, Uwe, Mekahli, Djalila, Le Meur, Yannick, Nijenhuis, Tom, Ong, Albert C M, Sayer, John A, Schaefer, Franz, Servais, Aude, Tesar, Vladimir, Torra, Roser, Walsh, Stephen B, Gansevoort, Ron T

“…ABSTRACT Approval of the vasopressin V2 receptor antagonist tolvaptan—based on the landmark TEMPO 3:4 trial—marked a transformation in the management of…”
Get full text

Biallelic inheritance of hypomorphic PKD1 variants is highly prevalent in very early onset polycystic kidney disease by Durkie, Miranda, Chong, Jiehan, Valluru, Manoj K., Harris, Peter C., Ong, Albert C.M.

“…To investigate the prevalence of biallelic PKD1 and PKD2 variants underlying very early onset (VEO) polycystic kidney disease (PKD) in a large international…”
Get full text

Recommendations for the use of tolvaptan in autosomal dominant polycystic kidney disease: a position statement on behalf of the ERA-EDTA Working Groups on Inherited Kidney Disorders and European Renal Best Practice by Gansevoort, Ron T, Arici, Mustafa, Benzing, Thomas, Birn, Henrik, Capasso, Giovambattista, Covic, Adrian, Devuyst, Olivier, Drechsler, Christiane, Eckardt, Kai-Uwe, Emma, Francesco, Knebelmann, Bertrand, Le Meur, Yannick, Massy, Ziad A, Ong, Albert C M, Ortiz, Alberto, Schaefer, Franz, Torra, Roser, Vanholder, Raymond, Więcek, Andrzej, Zoccali, Carmine, Van Biesen, Wim

“…Recently, the European Medicines Agency approved the use of the vasopressin V2 receptor antagonist tolvaptan to slow the progression of cyst development and…”
Get full text

Barriers and facilitators to the implementation of guidelines in rare diseases: a systematic review by Gittus, Matthew, Chong, Jiehan, Sutton, Anthea, Ong, Albert C M, Fotheringham, James

“…Rare diseases present a challenge to guideline implementation due to a low prevalence in the general population and the unfamiliarity of healthcare…”
Get full text

Targeting new cellular disease pathways in autosomal dominant polycystic kidney disease by Chang, Ming-Yang, C M Ong, Albert

“…Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of end-stage renal failure. Understanding the molecular and cellular…”
Get full text

Imaging of Kidney Cysts and Cystic Kidney Diseases in Children: An International Working Group Consensus Statement by Gimpel, Charlotte, Avni, E Fred, Breysem, Luc, Burgmaier, Kathrin, Caroli, Anna, Cetiner, Metin, Haffner, Dieter, Hartung, Erum A, Franke, Doris, König, Jens, Liebau, Max C, Mekahli, Djalila, Ong, Albert C M, Pape, Lars, Titieni, Andrea, Torra, Roser, Winyard, Paul J D, Schaefer, Franz

“…Kidney cysts can manifest as focal disease (simple and complex kidney cysts), affect a whole kidney (eg, multicystic dysplastic kidney or cystic dysplasia), or…”
Get full text

The Controversial Role of Fibrosis in Autosomal Dominant Polycystic Kidney Disease by Fragiadaki, Maria, Macleod, Fiona M, Ong, Albert C M

“…Autosomal Dominant Polycystic Kidney Disease (ADPKD) is characterized by the progressive growth of cysts but it is also accompanied by diffuse tissue scarring…”
Get full text

Hypertension in young adults with autosomal dominant polycystic kidney disease: a case for early screening? by Cadnapaphornchai, Melissa A, Ong, Albert C M

“…ADPKD is the most common hereditary kidney disease and a major cause of kidney failure world-wide. Significant kidney enlargement occurs decades preceding loss…”
Get full text

Renal monocyte chemoattractant protein-1: an emerging universal biomarker and therapeutic target for kidney diseases? by Tam, Frederick W K, Ong, Albert C M

Get full text

Regional variation in tolvaptan prescribing across England: national data and retrospective evaluation from an expert centre by Chong, Jiehan, Harris, Tess, Ong, Albert C M

“…Background Tolvaptan, a vasopressin V2 receptor antagonist, was approved in 2015 by the UK National Institute for Health and Care Excellence for use in…”
Get full text

Azulene‐Fused Acenes by Ong, Albert, Tao, Tao, Jiang, Qing, Han, Yi, Ou, Yaping, Huang, Kuo‐Wei, Chi, Chunyan

“…Non‐alternant non‐benzenoid π‐conjugated polycyclic hydrocarbons (PHs) are expected to exhibit very different electronic properties from the all‐benzenoid PHs…”
Get full text

Magnetic resonance imaging biomarkers for chronic kidney disease: a position paper from the European Cooperation in Science and Technology Action PARENCHIMA by Selby, Nicholas M, Blankestijn, Peter J, Boor, Peter, Combe, Christian, Eckardt, Kai-Uwe, Eikefjord, Eli, Garcia-Fernandez, Nuria, Golay, Xavier, Gordon, Isky, Grenier, Nicolas, Hockings, Paul D, Jensen, Jens D, Joles, Jaap A, Kalra, Philip A, Krämer, Bernhard K, Mark, Patrick B, Mendichovszky, Iosif A, Nikolic, Olivera, Odudu, Aghogho, Ong, Albert C M, Ortiz, Alberto, Pruijm, Menno, Remuzzi, Giuseppe, Rørvik, Jarle, de Seigneux, Sophie, Simms, Roslyn J, Slatinska, Janka, Summers, Paul, Taal, Maarten W, Thoeny, Harriet C, Vallée, Jean-Paul, Wolf, Marcos, Caroli, Anna, Sourbron, Steven

“…Functional renal magnetic resonance imaging (MRI) has seen a number of recent advances, and techniques are now available that can generate quantitative imaging…”
Get full text

Increased psychosocial risk, depression and reduced quality of life living with autosomal dominant polycystic kidney disease by Simms, Roslyn J, Thong, Kah Mean, Dworschak, Gabriel C, Ong, Albert C M

“…The psychosocial impact of living with autosomal dominant polycystic kidney disease (ADPKD) is poorly understood. In this study, we assessed the overall…”
Get full text

Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype by Senum, Sarah R., Li, Ying (Sabrina) M., Benson, Katherine A., Joli, Giancarlo, Olinger, Eric, Lavu, Sravanthi, Madsen, Charles D., Gregory, Adriana V., Neatu, Ruxandra, Kline, Timothy L., Audrézet, Marie-Pierre, Outeda, Patricia, Nau, Cherie B., Meijer, Esther, Ali, Hamad, Steinman, Theodore I., Mrug, Michal, Phelan, Paul J., Watnick, Terry J., Peters, Dorien J.M., Ong, Albert C.M., Conlon, Peter J., Perrone, Ronald D., Cornec-Le Gall, Emilie, Hogan, Marie C., Torres, Vicente E., Sayer, John A., Harris, Peter C.

“…Autosomal dominant polycystic kidney disease (ADPKD), characterized by progressive cyst formation/expansion, results in enlarged kidneys and often end stage…”
Get full text