Search Results - "Oneal, Patricia"

FDA Approval Summary: Vemurafenib for the Treatment of Patients with Erdheim‐Chester Disease with the BRAFV600 Mutation by Oneal, Patricia A., Kwitkowski, Virginia, Luo, Lola, Shen, Yuan Li, Subramaniam, Sriram, Shord, Stacy, Goldberg, Kirsten B., McKee, Amy E., Kaminskas, Edvardas, Farrell, Ann, Pazdur, Richard

“…On November 6, 2017, the U.S. Food and Drug Administration (FDA) granted regular approval to vemurafenib for the treatment of adult patients with…”
Get full text

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin by Miller, Jeffery L, Tanno, Toshihiko, Bhanu, Natarajan V, Oneal, Patricia A, Goh, Sung-Ho, Staker, Pamela, Lee, Y Terry, Moroney, John W, Reed, Christopher H, Luban, Naomi LC, Wang, Rui-Hong, Eling, Thomas E, Childs, Richard, Ganz, Tomas, Leitman, Susan F, Fucharoen, Suthat

“…In thalassemia, deficient globin-chain production during erythropoiesis results in anemia. Thalassemia may be further complicated by iron overload (frequently…”
Get full text

Acute chest syndrome: sickle cell disease by Paul, Rabindra N., Castro, Oswaldo L., Aggarwal, Anita, Oneal, Patricia A.

“…Acute chest syndrome (ACS) is a common complication and reason for hospital admission in patients with sickle cell disease (SCD). It is also the most common…”
Get full text

FDA Approval Summary: Vemurafenib for the Treatment of Patients with Erdheim-Chester Disease with the BRAF V600 Mutation by Oneal, Patricia A, Kwitkowski, Virginia, Luo, Lola, Shen, Yuan Li, Subramaniam, Sriram, Shord, Stacy, Goldberg, Kirsten B, McKee, Amy E, Kaminskas, Edvardas, Farrell, Ann, Pazdur, Richard

“…On November 6, 2017, the U.S. Food and Drug Administration (FDA) granted regular approval to vemurafenib for the treatment of adult patients with…”
Get full text

Multicenter COMPACT study of COMplications in Patients with sickle cell disease And utilization of iron Chelation Therapy by Jordan, Lanetta, Adams-Graves, Patricia, Kanter-Washko, Julie, Oneal, Patricia A., Sasane, Medha, Vekeman, Francis, Bieri, Christine, Magestro, Matthew, Marcellari, Andrea, Duh, Mei Sheng

“…Abstract Background: Over the past few decades, lifespans of sickle cell disease (SCD) patients have increased; hence, they encounter multiple complications…”
Get full text

Pernicious Anemia with Autoimmune Hemolytic Anemia: A Case Report and Literature Review by Yeruva, Sri Lakshmi Hyndavi, Oneal, Patricia, Manchandani, Raj Pal

“…Pernicious anemia is a common cause of vitamin B12 deficiency. Here, we discuss a case of a young woman who presented with severe anemia along with a history…”
Get full text

Increased iron export by ferroportin induces restriction of HIV-1 infection in sickle cell disease by Kumari, Namita, Ammosova, Tatiana, Diaz, Sharmin, Lin, Xionghao, Niu, Xiaomei, Ivanov, Andrey, Jerebtsova, Marina, Dhawan, Subhash, Oneal, Patricia, Nekhai, Sergei

“…The low incidence of HIV-1 infection in patients with sickle cell disease (SCD) and inhibition of HIV-1 replication in vitro under the conditions of low…”
Get full text

Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming by Sripichai, Orapan, Kiefer, Christine M., Bhanu, Natarajan V., Tanno, Toshihiko, Noh, Seung-Jae, Goh, Sung-Ho, Russell, J. Eric, Rognerud, Cheryl L., Ou, Ching-Nan, Oneal, Patricia A., Meier, Emily R., Gantt, Nicole M., Byrnes, Colleen, Lee, Y. Terry, Dean, Ann, Miller, Jeffery L.

“…Therapeutic regulation of globin genes is a primary goal of translational research aimed toward hemoglobinopathies. Signal transduction was used to identify…”
Get full text

Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location by Ogbonna, Onyekachi Henry, Sakruti, Susmita, Sulieman, Maha, Ali, Ahmed, Shokrani, Babak, Oneal, Patricia

“…Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor distinguished by having both hepatoid and adenomatous features, which can make the diagnosis…”
Get full text

Prevalence of Sickle Cell Trait and Rare Hemoglobin Variants in the Metropolitan Washington DC Area by Niu, Xiaomei, Parry, Christian S., Mason, Angela, Harrison, Barbara, Nouraie, Seyed Mehdi, Ammosova, Tatiana, Salomon-Andonie, Juan, Oneal, Patricia A., Gordeuk, Victor R., Taylor, James G., VI, Nekhai, Sergei

Get full text

End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain by Farrell, Ann T., Panepinto, Julie, Carroll, C. Patrick, Darbari, Deepika S., Desai, Ankit A., King, Allison A., Adams, Robert J., Barber, Tabitha D., Brandow, Amanda M., DeBaun, Michael R., Donahue, Manus J., Gupta, Kalpna, Hankins, Jane S., Kameka, Michelle, Kirkham, Fenella J., Luksenburg, Harvey, Miller, Shirley, Oneal, Patricia Ann, Rees, David C., Setse, Rosanna, Sheehan, Vivien A., Strouse, John, Stucky, Cheryl L., Werner, Ellen M., Wood, John C., Zempsky, William T.

“…To address the global burden of sickle cell disease (SCD) and the need for novel therapies, the American Society of Hematology partnered with the US Food and…”
Get full text

Aromatase Inhibitor-Induced Erythrocytosis in a Patient Undergoing Hormonal Treatment for Breast Cancer by Oneal, Patricia, Ogbonna, Onyekachi Henry, Nwabudike, Stanley Madu, Yeruva, Sri Lakshmi Hyndavi

“…Aromatase inhibitors (AIs) are most commonly used for breast cancer patients with hormone receptor positive disease. Although the side effect profile of…”
Get full text

Fetal hemoglobin silencing in humans by Oneal, Patricia A., Gantt, Nicole M., Schwartz, Joseph D., Bhanu, Natarajan V., Lee, Y. Terry, Moroney, John W., Reed, Christopher H., Schechter, Alan N., Luban, Naomi L.C., Miller, Jeffery L.

“…Interruption of the normal fetal-to-adult transition of hemoglobin expression should largely ameliorate sickle cell and beta-thalassemia syndromes. Achievement…”
Get full text

Sepsis caused by Mycobacterium terrae complex in a patient with sickle cell disease by Esnakula, Ashwini K, Mummidi, Sudhir K, Oneal, Patricia A, Naab, Tammey J

“…Infections are a significant cause of morbidity and mortality in patients with sickle cell disease. Loss of splenic function in these patients makes them…”
Get full text

End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings by Farrell, Ann T., Panepinto, Julie, Desai, Ankit A., Kassim, Adetola A., Lebensburger, Jeffrey, Walters, Mark C., Bauer, Daniel E., Blaylark, Rae M., DiMichele, Donna M., Gladwin, Mark T., Green, Nancy S., Hassell, Kathryn, Kato, Gregory J., Klings, Elizabeth S., Kohn, Donald B., Krishnamurti, Lakshmanan, Little, Jane, Makani, Julie, Malik, Punam, McGann, Patrick T., Minniti, Caterina, Morris, Claudia R., Odame, Isaac, Oneal, Patricia Ann, Setse, Rosanna, Sharma, Poornima, Shenoy, Shalini

“…To address the global burden of sickle cell disease and the need for novel therapies, the American Society of Hematology partnered with the US Food and Drug…”
Get full text

Faculty Perspective on Interprofessional Education Competencies: Respiratory Therapy Compared to Other Allied Health Professions by Behr, Amanda Yarberry, O'Neal, Patricia Marie, Maldonado, Dominique, Truelove, Jr, Christopher A, De Leo, Gianluca

“…Interprofessional Education (IPE) provides a framework for collaborative education between health care specialties to improve patient care. In 2010, the…”
Get full text

A Novel Use of Early Radiation Therapy in the Treatment of Hyperbilirubinemia in a Patient with Primary Hepatic Lymphoma and Chronic Hepatitis C by Tammana, Venkata S., Begum, Rehana, Oneal, Patricia, Karpurapu, Hemamalini, Muley, Amruta, Yeruva, Sri Lakshmi Hyndavi, Dunmore-Griffith, Jacquelyn, Mekonen, Eyasu, Hasan, Nabhani

“…Lymphomas arising in the liver are extremely rare. Here, we describe a case of Hepatitis C virus infection with primary hepatic lymphoma (PHL) presenting with…”
Get full text

Inhibition of erythroblast growth and fetal hemoglobin production by ribofuranose-substituted adenosine derivatives by Bhanu, Natarajan V., Lee, Y. Terry, Oneal, Patricia A., Gantt, Nicole M., Aerbajinai, Wulin, Noel, Pierre, Thomas, Craig J., Miller, Jeffery L.

“…In vivo, inhibition of fetal hemoglobin (HbF) expression in humans around the time of birth causes the clinical manifestation of sickle cell and…”
Get full text

Hydroxycarbamide treatment in sickle cell disease: estimates of possible leukaemia risk and of hospitalization survival benefit by Castro, Oswaldo, Nouraie, Mehdi, Oneal, Patricia

“…Summary Using health insurance claims databases we compared the frequency/incidence of acute myeloid leukaemia (AML) and inpatient mortality in sickle cell…”
Get full text

Survival Among Minority Populations with Chronic Myeloid Leukemia: A Surveillance Epidemiology and End Results Database Analysis by Agbedia, Owhofasa, Ngwa, Julius, Darbari, Deepika S., Oneal, Patricia

“…Introduction: Cancer affects people of all races in the U.S.; however, the burden is greater for minority populations. This is influenced by factors such as…”
Get full text