Search Results - "Ondra, T"

Optimized adaptive enrichment designs by Ondra, Thomas, Jobjörnsson, Sebastian, Beckman, Robert A, Burman, Carl-Fredrik, König, Franz, Stallard, Nigel, Posch, Martin

“…Based on a Bayesian decision theoretic approach, we optimize frequentist single- and adaptive two-stage trial designs for the development of targeted…”
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Optimizing Trial Designs for Targeted Therapies by Ondra, Thomas, Jobjörnsson, Sebastian, Beckman, Robert A, Burman, Carl-Fredrik, König, Franz, Stallard, Nigel, Posch, Martin

“…An important objective in the development of targeted therapies is to identify the populations where the treatment under consideration has positive benefit…”
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Recent advances in methodology for clinical trials in small populations: the InSPiRe project by Friede, T, Posch, M, Zohar, S, Alberti, C, Benda, N, Comets, E, Day, S, Dmitrenko, A, Graf, A, Günhan, B. K, Hee, S. W, Lentz, F, Madan, J, Miller, F, Ondra, T, Pearce, M, Röver, C, Tournazi, A, Unkel, S, Ursino, M, Wassmer, G, Stallard, N

“…Orphanet Journal of Rare Diseases, 13:136, 2018 Where there are a limited number of patients, such as in a rare disease, clinical trials in these small…”
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