Search Results - "Oncel, Sema"

Sustained intestinal epithelial monolayer wound closure after transient application of a FAK-activating small molecule by Oncel, Sema, Wang, Qinggang, Elsayed, Ahmed Adham R, Vomhof-DeKrey, Emilie E, Brown, Nicholas D, Golovko, Mikhail Y, Golovko, Svetlana A, Gallardo-Macias, Ricardo, Gurvich, Vadim J, Basson, Marc D

“…M64HCl, which has drug-like properties, is a water-soluble Focal Adhesion Kinase (FAK) activator that promotes murine mucosal healing after ischemic or…”
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Efficacy of Butyrate to Inhibit Colonic Cancer Cell Growth Is Cell Type-Specific and Apoptosis-Dependent by Oncel, Sema, Safratowich, Bryan D, Lindlauf, James E, Liu, Zhenhua, Palmer, Daniel G, Briske-Anderson, Mary, Zeng, Huawei

“…Increasing dietary fiber consumption is linked to lower colon cancer incidence, and this anticancer effect is tied to elevated levels of short-chain fatty…”
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Comparison of the Efficacy of Transcutaneous Electrical Nerve Stimulation, Interferential Currents, and Shortwave Diathermy in Knee Osteoarthritis: A Double-Blind, Randomized, Controlled, Multicenter Study by Atamaz, Funda C., MD, Durmaz, Berrin, MD, Baydar, Meltem, MD, Demircioglu, Ozlem Y., MD, Iyiyapici, Ayse, MD, Kuran, Banu, MD, Oncel, Sema, MD, Sendur, Omer F., MD

“…Abstract Atamaz FC, Durmaz B, Baydar M, Demircioglu OY, Iyiyapici A, Kuran B, Oncel S, Sendur OF. Comparison of the efficacy of transcutaneous electrical nerve…”
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ZINC40099027 Promotes Gastric Mucosal Repair in Ongoing Aspirin-Associated Gastric Injury by Activating Focal Adhesion Kinase by Oncel, Sema, Gupta, Rashmi, Wang, Qinggang, Basson, Marc D

“…Nonsteroidal anti-inflammatory drugs cause gastric ulcers and gastritis. No drug that treats GI injury directly stimulates mucosal healing. ZINC40099027 (ZN27)…”
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A novel drug-like water-soluble small molecule Focal Adhesion Kinase (FAK) activator promotes intestinal mucosal healing by Wang, Qinggang, Gallardo-Macias, Ricardo, Vomhof-DeKrey, Emilie E., Gupta, Rashmi, Golovko, Svetlana A., Golovko, Mikhail Y., Oncel, Sema, Gurvich, Vadim J., Basson, Marc D.

“…Non-steroidal anti-inflammatory drugs (NSAIDs) injure the proximal and distal gut by different mechanisms. While many drugs reduce gastrointestinal injury, no…”
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Prevalence of Rheumatoid Arthritis and Spondyloarthritis in Turkey: A Nationwide Study by Tuncer, Tiraje, Gilgil, Erdal, Kaçar, Cahit, Kurtaiş, Yeşim, Kutlay, Şehim, Bütün, Bülent, Yalçin, Peyman, Akarirmak, Ülkü, Altan, Lale, Ardiç, Füsun, Ardiçoğlu, Özge, Altay, Zuhal, Cantürk, Ferhan, Cerrahoğlu, Lale, Çevik, Remzi, Demir, Hüseyin, Durmaz, Berrin, Dursun, Nigar, Duruöz, Tuncay, Erdoğan, Canan, Evcik, Deniz, Gürsoy, Savaş, Hizmetli, Sami, Kaptanoğlu, Ece, Kayhan, Önder, Kirnap, Mehmet, Kokino, Siranuş, Kozanoğlu, Erkan, Kuran, Banu, Nas, Kemal, Öncel, Sema, Sindel, Dilşad, Orkun, Sevim, Sarpel, Tunay, Savaş, Serpil, Şendur, Ömer Faruk, Şenel, Kazım, Uğurlu, Hatice, Uzunca, Kaan, Tekeoğlu, İbrahim, Guillemin, Francis

“…This study aims to estimate the prevalence of rheumatoid arthritis (RA) and spondyloarthritis (SpA) in Turkey using the same telephone questionnaire developed…”
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Su239 SMALL MOLECULE ZINC4009927 PROMOTES CHRONIC ASPIRIN-ASSOCIATED GASTROINTESTINAL MUCOSAL INJURY BY ACTIVATING FOCAL ADHESION KINASE by Oncel, Sema, Basson, Marc D.

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Front Cover: The Protective Potential of Butyrate against Colon Cancer Cell Migration and Invasion Is Critically Dependent on Cell Type by Oncel, Sema, Safratowich, Bryan D., Zeng, Huawei

“…Mol. Nutr. Food Res. 2024, 68, 2400421 DOI: 10.1002/mnfr.202400421 The cover image is based on the Article The Protective Potential of Butyrate against Colon…”
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Gut homeostasis, injury, and healing: New therapeutic targets by Oncel, Sema, Basson, Marc D

“…The integrity of the gastrointestinal mucosa plays a crucial role in gut homeostasis, which depends upon the balance between mucosal injury by destructive…”
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The Protective Potential of Butyrate against Colon Cancer Cell Migration and Invasion Is Critically Dependent on Cell Type by Oncel, Sema, Safratowich, Bryan D., Zeng, Huawei

“…Scope Short‐chain fatty acids such as butyrate are produced through the fermentation of dietary fiber by colonic bacteria. Preclinical studies indicate an…”
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ZINC40099027 promotes monolayer circular defect closure by a novel pathway involving cytosolic activation of focal adhesion kinase and downstream paxillin and ERK1/2 by Oncel, Sema, Basson, Marc D.

“…ZINC40099027 (ZN27) is a specific focal adhesion kinase (FAK) activator that promotes murine mucosal wound closure after ischemic or NSAID-induced injury…”
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An investigation into the effects of kinesiotaping for posture correction on kyphosis angle, pain, and balance in patients with postmenopausal osteoporosis-associated thoracic kyphosis by Bulut, Deniz, Dilek, Banu, Kılınç, Adem, Ellidokuz, Hülya, Öncel, Sema

“…Summary Although positive effect of kinesiotaping in reducing back pain in addition to exercise was observed in 6-week follow-up, no additional contribution to…”
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The relation between tooth loss and bone mass in postmenopausal osteoporotic women in Turkey: a multicenter study by GUR, Ali, NAS, Kemal, GUNDUZ, O. Hakan, ERSOY, Yuksel, ALTAY, Zuhal, OZTURK, Cihat, AKKUS, Selami, SENOCAK, Ozlem, KAVUNCU, Vural, KIRNAP, Mehmet, TEKEOGLU, Ibrahim, ERDOGAN, Ferda, KAYHAN, Onder, SARAC, Aysegul J, DEMIRALP, Levent, DEMIRKESEN, Atilla, ADAM, Mehmet, ATAY, Mesut Birol, AKYUZ, Gulseren, SINDAL, Dilsad, AKSIT, Ramazan, ONCEL, Sema, DILSEN, Guzin, CEVIK, Remzi

“…The purpose of this study was to investigate the associations of tooth loss with skeletal bone mass, years since menopause, educational level, current smoking…”
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The Protective Potential of Butyrate Against Colon Cancer Cells Is Critically Dependent on Cell Type by Oncel, Sema, Lindlauf, James, Zeng, Huawei

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Updated approach for the management of osteoporosis in Turkey: a consensus report by Kirazlı, Yeşim, Atamaz Çalış, Funda, El, Özlem, Gökçe Kutsal, Yeşim, Peker, Özlen, Sindel, Dilsad, Tuzun, Şansın, Gogas Yavuz, Dilek, Durmaz, Berrin, Akarirmak, Ülkü, Bodur, Hatice, Hamuryudan, Vedat, Inceboz, Umit, Öncel, Sema

“…Summary As a result of the current demographics, increased projections of osteoporosis (OP) and prevalence of the disease in Turkey, a panel of…”
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The Effect of Short-Wave Diathermy and Exercise on Depressive Affect in Chronic Low Back Pain Patients by Karasel, Seide, Oncel, Sema, Sonmez, Ipek

“…The aim of this study was to compare exercise, continuous short-wave diathermy (SWD) and intermittent SWD treatment modalities and to evaluate the effects of…”
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Effects of Small Molecule FAK Activators on Gastrointestinal Mucosal Healing by Oncel, Sema

“…Gastrointestinal (GI) ulcers are common worldwide. The persistence of noxious agents such as gastric acid, pepsin, nonsteroidal anti-inflammatory drugs…”
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471 REFINEMENT OF SMALL MOLECULE FOCAL ADHESION KINASE ACTIVATORS TO PROMOTE INTESTINAL MUCOSAL HEALING by Wang, Qinggang, Gallardo-Macias, Ricardo, Rashmi, Rashmi, Oncel, Sema, Gurvich, Vadim J., Basson, Marc D.

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Discovery of Novel Small-Molecule FAK Activators Promoting Mucosal Healing by Wang, Qinggang, Gallardo-Macias, Ricardo, Rashmi, Golovko, Mikhail Y, Elsayed, Ahmed Adham Raafat, More, Shyam K, Oncel, Sema, Gurvich, Vadim J, Basson, Marc D

“…Gastrointestinal mucosal wounds are common to patients injured by factors as diverse as drugs, inflammatory bowel disease, peptic ulcers, and necrotizing…”
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Treatment of carpal tunnel syndrome with nerve and tendon gliding exercises by AKALIN, Elif, EL, Özlem, PEKER, Özlen, SENOCAK, Özlem, TAMCI, Sebnem, GÜLBAHAR, Selmin, CAKMUR, Raif, ÖNCEL, Sema

“…To assess the effect of nerve and tendon gliding exercises in carpal tunnel syndrome. The study was a prospective, randomized, before-and-after treatment…”
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