Search Results - "Onat, Filiz Yılmaz"

IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence by Akin, Demet, Ravizza, Teresa, Maroso, Mattia, Carcak, Nihan, Eryigit, Tugba, Vanzulli, Ilaria, Aker, Rezzan Gülhan, Vezzani, Annamaria, Onat, Filiz Yılmaz

“…Abstract Interleukin (IL)-1β plays a crucial role in the mechanisms of limbic seizures in rodent models of temporal lobe epilepsy. We addressed whether…”
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Suppressive effect of Rho-kinase inhibitors Y-27632 and fasudil on spike-and-wave discharges in genetic absence epilepsy rats from Strasbourg (GAERS) by Çarçak, Nihan, Yavuz, Melis, Eryiğit Karamahmutoğlu, Tuğba, Kurt, Akif Hakan, Urhan Küçük, Meral, Onat, Filiz Yılmaz, Büyükafsar, Kansu

“…Rho/Rho-kinase (ROCK) signaling contributes to neuroinflammation, epileptogenesis, and seizures in convulsive-type epilepsies. However, this pathway has not…”
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The effect of serum levetiracetam concentrations on therapeutic response and IL1-beta concentration in patients with epilepsy by Gulcebi, Medine I., Kendirli, Tansel, Turgan, Zehra Asik, Patsalos, Philip N., Yilmaz Onat, Filiz

“…•Maximum serum concentration (Cmax) of levetiracetam may be a better indicator of therapeutic response and for development of adverse effects.•Consequently,…”
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Effect of U-92032, T-Type Ca2+ Channel Blocker, on Rats with Genetic Absence Epilepsy by Yananli, Hasan Raci, Demirkapu, Mahluga Jafarova, Sakallı, Halil Eren, Gülhan, Rezzan, Onat, Filiz Yılmaz

“…Absence epilepsy is associated with diffuse spike-and-wave discharges (SWD) on the electroencephalogram (EEG). Recent studies have demonstrated that the…”
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Cardiovascular Regulation through Hypothalamic GABAA Receptors in a Genetic Absence Epilepsy Model in Rat by Aker, Rezzan Gülhan, Onat, Filiz Yılmaz

“…Purpose: γ‐Aminobutyric acid (GABA) plays a vital role in both central cardiovascular homeostasis and pathogenesis of epilepsy. Epilepsy affects autonomic…”
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The relationship between age-related development of spike-and-wave discharges and the resistance to amygdaloid kindling in rats with genetic absence epilepsy by Çarçak, Nihan, Aker, Rezzan Gülhan, Özdemir, Osman, Demiralp, Tamer, Onat, Filiz Yılmaz

“…Abstract Genetic Absence Epilepsy Rats from Strasbourg (GAERS) are resistant to amygdaloid kindling. Since in GAERS the characteristics of spike-and-wave…”
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Animal models of absence epilepsies: What do they model and do sex and sex hormones matter? by van Luijtelaar, Gilles, Onat, Filiz Yilmaz, Gallagher, Martin J

“…Abstract While epidemiological data suggest a female prevalence in human childhood- and adolescence-onset typical absence epilepsy syndromes, the sex…”
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The involvement of limbic structures in typical and atypical absence epilepsy by Onat, Filiz Yılmaz, van Luijtelaar, Gilles, Nehlig, Astrid, Snead, O. Carter

“…Summary Typical and atypical seizures of absence epilepsy are thought to be generated by a rhythmogenic interplay between the cortex and the thalamus. However,…”
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The role of the substantia nigra pars reticulata in kindling resistance in rats with genetic absence epilepsy by Akman, Ozlem, Gulcebi, Medine I., Carcak, Nihan, Ketenci Ozatman, Sema, Eryigit, Tugba, Moshé, Solomon L., Galanopoulou, Aristea S., Onat, Filiz Yilmaz

“…Summary Objective Genetic Absence Epilepsy Rats from Strasbourg (GAERS) show a resistance to secondary generalization of focal limbic seizures evoked by…”
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The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy by Gulcebi, Medine Idrizoglu, Ozkaynakcı, Aydan, Goren, Mehmet Zafer, Aker, Rezzan Gulhan, Ozkara, Cigdem, Onat, Filiz Yılmaz

“…Summary Lamotrigine (LTG) which has a widespread use in epilepsy treatment as an antiepileptic agent is metabolized by UDP-glucuronosyl transferase (UGT)…”
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Cardiovascular regulation through hypothalamic GABA(A) receptors in a genetic absence epilepsy model in rat by Aker, Rezzan Gülhan, Onat, Filiz Yilmaz

“…Gamma-aminobutyric acid (GABA) plays a vital role in both central cardiovascular homeostasis and pathogenesis of epilepsy. Epilepsy affects autonomic nervous…”
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Localized cortical injections of ethosuximide suppress spike-and-wave activity and reduce the resistance to kindling in genetic absence epilepsy rats (GAERS) by Gülhan Aker, Rezzan, Tezcan, Kutluhan, Çarçak, Nihan, Sakallı, Eren, Akın, Demet, Onat, Filiz Yılmaz

“…Summary Models of genetic absence epilepsy are resistant to secondary generalization of focal limbic seizures. This correlates with the postnatal development…”
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Effect of systemic and intracortical administration of phenytoin in two genetic models of absence epilepsy by Gurbanova, Ayten A, Aker, Rezzan, Berkman, Kemal, Onat, Filiz Yilmaz, Rijn, Clementana M, Luijtelaar, Gilles

“…1 Spontaneous 7–10 Hz spike‐wave discharges (SWDs) are the electroencephalographic hallmark of absence seizures, as can be observed in WAG/Rij as well as in…”
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Amygdala Kindling in the WAG/Rij Rat Model of Absence Epilepsy by Aker, Rezzan Gülhan, Yananli, Hasan Raci, Gurbanova, Ayten Azizova, Özkaynakçi, Aydan Ergün, Ateş, Nurbay, Luijtelaar, Gilles, Onat, Filiz Yilmaz

“…Purpose: The kindling model in rats with genetic absence epilepsy is suitable for studying mechanisms involved in the propagation and generalization of seizure…”
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INCREASED INHIBITORY SYNAPTIC ACTIVITY IN THE HIPPOCAMPUS (CA1) OF GENETIC ABSENCE EPILEPSY RATS: RELEVANCE OF KINDLING RESISTANCE by Çarçak, Nihan, Dileköz, Ergin, Gülhan, Rezzan, Onur, Rüştü, Onat, Filiz Yılmaz, Sara, Yıldırım

“…Highlights • Kindling resistance was overcome by the administration of supra-threshold stimuli, however reaching stage 5 was still delayed in GAERS compared to…”
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Workshop on Idiopathic Generalized Epilepsies: Bridging basic science and clinical research (October 3–6, 2007; Antalya, Turkey) by Bertram, Edward H., Onat, Filiz Yilmaz, Ozkara, Cigdem, Moshé, Solomon L., Avanzini, Giuliano

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The Effect of Generalized Absence Seizures on the Progression of Kindling in the Rat by Onat, Filiz Yılmaz, Aker, Rezzan Gülhan, Gurbanova, Ayten Azizova, Ateş, Nurbay, Van Luijtelaar, Gilles

“…The involvement of the thalamus in limbic epileptogenesis has recently drawn attention to the connectivity between the nuclei of the thalamus and limbic…”
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Prolongation of absence seizures and changes in serotonergic and dopaminergic neurotransmission by nigrostriatal pathway degeneration in genetic absence epilepsy rats by Tugba, Eryigit Karamahmutoglu, Medine, Gulcebi Idriz Oglu, Ozlem, Akman, Deniz, Kirik, Filiz, Onat Yilmaz

“…Basal ganglia structures play an important role in the pathophysiology of absence epilepsy, known as remote control of absence seizures. We examined the role…”
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Changes in Baroreflex Responses of Kindled Rats by Kaya, Çiğdem Apaydin, Özkaynakçi, Aydan Ergün, Gören, M. Zafer, Onat, Filiz Yilmaz

“…Purpose: This study was planned to investigate the baroreflex responses (BRs) in kindled rats during seizure‐free period to put forward new data on cardiac…”
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Enhancement of spike and wave discharges by microinjection of bicuculline into the reticular nucleus of rats with absence epilepsy by Aker, Rezzan Gülhan, Özkara, Çiğdem, Dervent, Ayşın, Yılmaz Onat, Filiz

“…The aim of this study was to demonstrate the effect of administration of gamma-aminobutyric acid (GABA) A receptor antagonist, bicuculline, into the reticular…”
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