Search Results - "On, Ngoc"

Transporter-based delivery of anticancer drugs to the brain: improving brain penetration by minimizing drug efflux at the blood-brain barrier by On, Ngoc H, Miller, Donald W

“…The delivery of many drugs to the central nervous system (CNS) is limited due to the restrictive nature of the blood-brain barrier (BBB). The reduced…”
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The Dahu graph-cut for interactive segmentation on 2D/3D images by Ôn Vũ Ngọc, Minh, Carlinet, Edwin, Fabrizio, Jonathan, Géraud, Thierry

“…•An efficient method to compute the Dahu pseudo-distance on multivariate images.•A new interactive segmentation method (based on the Dahu…”
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Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells by Mitchell, Ryan W., On, Ngoc H., Del Bigio, Marc R., Miller, Donald W., Hatch, Grant M.

“…J. Neurochem. (2011) 117, 735–746. The blood‐brain barrier (BBB), formed by the brain capillary endothelial cells, provides a protective barrier between the…”
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Rapid and Reversible Enhancement of Blood–Brain Barrier Permeability Using Lysophosphatidic Acid by On, Ngoc H, Savant, Sanjot, Toews, Myron, Miller, Donald W

“…The present study characterizes the effects of lysophosphatidic acid (LPA) on blood–brain barrier (BBB) permeability focusing specifically on the time of…”
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Examination of blood–brain barrier (BBB) integrity in a mouse brain tumor model by On, Ngoc H., Mitchell, Ryan, Savant, Sanjot D., Bachmeier, Corbin. J., Hatch, Grant M., Miller, Donald W.

“…The present study evaluates, both functionally and biochemically, brain tumor-induced alterations in brain capillary endothelial cells. Brain tumors were…”
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Modulation of Blood–Brain Barrier Permeability in Mice Using Synthetic E‑Cadherin Peptide by On, Ngoc H, Kiptoo, Paul, Siahaan, Teruna J, Miller, Donald W

“…The present work characterizes the effects of synthetic E-cadherin peptide (HAV) on blood–brain barrier (BBB) integrity using various techniques including…”
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Pharmacokinetics of a once-daily tacrolimus formulation in first nations and caucasian liver transplant recipients by Peretz, David, On, Ngoc H, Miller, Donald, Kim, Richard, Franklin, Carla, Dascal, Roman, Knowles, Cori, Minuk, Gerald Y

“…Patient ethnicity may influence the pharmacokinetics (PK) of tacrolimus. Because the Canadian First Nations (FN) constitute a large and increasing segment of…”
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Comparison of Linear and Cyclic His-Ala-Val Peptides in Modulating the Blood-Brain Barrier Permeability: Impact on Delivery of Molecules to the Brain by Alaofi, Ahmed, On, Ngoc, Kiptoo, Paul, Williams, Todd D, Miller, Donald W, Siahaan, Teruna J

“…The aim of this study is to evaluate the effect of peptide cyclization on the blood-brain barrier (BBB) modulatory activity and plasma stability of His-Ala-Val…”
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Modulation of intercellular junctions by cyclic-ADT peptides as a method to reversibly increase blood-brain barrier permeability by Laksitorini, Marlyn D, Kiptoo, Paul K, On, Ngoc H, Thliveris, James A, Miller, Donald W, Siahaan, Teruna J

“…It is challenging to deliver molecules to the brain for diagnosis and treatment of brain diseases. This is primarily because of the presence of the blood-brain…”
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Exogenous arachidonic acid mediates permeability of human brain microvessel endothelial cells through prostaglandin E2 activation of EP3 and EP4 receptors by Dalvi, Siddhartha, Nguyen, Hieu H., On, Ngoc, Mitchell, Ryan W., Aukema, Harold M., Miller, Donald W., Hatch, Grant M.

“…The blood–brain barrier, formed by microvessel endothelial cells, is the restrictive barrier between the brain parenchyma and the circulating blood…”
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Assessment of P-glycoprotein Activity in the Blood-Brain Barrier (BBB) Using Near Infrared Fluorescence (NIRF) Imaging Techniques by On, Ngoc H., Chen, Fang, Hinton, Martha, Miller, Donald W.

“…ABSTRACT Purpose To examine functional activity of P-glycoprotein (P-gp) in the blood-brain barrier (BBB) using near infrared fluorescence (NIRF) imaging…”
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Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors by Sajesh, Babu V., On, Ngoc H., Omar, Refaat, Alrushaid, Samaa, Kopec, Brian M., Wang, Wei-Guang, Sun, Han-Dong, Lillico, Ryan, Lakowski, Ted M., Siahaan, Teruna J., Davies, Neal M., Puno, Pema-Tenzin, Vanan, Magimairajan Issai, Miller, Donald W.

“…The blood-brain barrier (BBB) poses a major obstacle by preventing potential therapeutic agents from reaching their intended brain targets at sufficient…”
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Improving Brain Delivery of Biomolecules via BBB Modulation in Mouse and Rat: Detection using MRI, NIRF, and Mass Spectrometry by Ulapane, Kavisha R, On, Ngoc, Kiptoo, Paul, Williams, Todd D, Miller, Donald W, Siahaan, Teruna J

“…There is an urgent need to develop new and alternative methods to deliver functional biomolecules to the brain for diagnosis and treatment of brain diseases…”
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Automatic vectorization of historical maps: A benchmark by Chen, Yizi, Chazalon, Joseph, Carlinet, Edwin, Ôn Vũ Ngoc, Minh, Mallet, Clément, Perret, Julien

“…Shape vectorization is a key stage of the digitization of large-scale historical maps, especially city maps that exhibit complex and valuable details. Having…”
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A minimum barrier distance for multivariate images with applications by Ôn Vũ Ngọc, Minh, Boutry, Nicolas, Fabrizio, Jonathan, Géraud, Thierry

“…Distance transforms and the saliency maps they induce are widely used in image processing, computer vision, and pattern recognition. The minimum barrier…”
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The solution to local climate adapting of French colonial public buildings in Indochina by Nhi, On Ngoc Yen, Hai, Truong Thanh, Van Thuong, Le

“…Between colonial conquests in Indochina, France created the first exchanges in culture, politics, economy, et cetera, especially architecture. Later, this…”
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DIPG-18. SONIC HEDGEHOG (SHH) SIGNALLING PROMOTES BLOOD BRAIN BARRIER (BBB) INTEGRITY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) by Sajesh, Babu, On, Ngoc, Donald, Miller, Kazina, Colin, Serletis, Demitre, Del-Bigio, Marc, Krawitz, Sherry, Hulleman, Esther, Vanan, Magimairajan Issai

“…Abstract DIPG is the most common brainstem tumor in children and is uniformly fatal. The BBB is intact in DIPG and plays an active role in restricting the…”
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Reduction in cardiolipin decreases mitochondrial spare respiratory capacity and increases glucose transport into and across human brain cerebral microvascular endothelial cells by Nguyen, Hieu M., Mejia, Edgard M., Chang, Wenguang, Wang, Ying, Watson, Emily, On, Ngoc, Miller, Donald W., Hatch, Grant M.

“…Microvessel endothelial cells form part of the blood–brain barrier, a restrictively permeable interface that allows transport of only specific compounds into…”
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Transient Modulation of Blood-brain Barrier with E-cadherin Peptide Improves Adenanthin Penetration into the Brain for the Treatment of Medulloblastoma by On, Ngoc, Alrushaia, Samma, Davies, Neal, Babu, Sajesh, Vanan, Magimairajan, Siahaan, Teruna, Miller, Donald

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Exogenous Arachidonic Acid Mediates Permeability of Human Brain Microvessel Endothelial Cells through Prostaglandin E 2 Activation of EP 3 and EP 4 Receptors by Dalvi, Siddhartha, Nguyen, Hieu, On, Ngoc, Mitchell, Ryan, Aukema, Harold, Miller, Donald, Hatch, Grant

“…Abstract only The blood‐brain barrier, formed by microvessel endothelial cells, is the restrictive barrier between the brain parenchyma and the circulating…”
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