Search Results - "Omilian, Angela"
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1
Effect of neighborhood deprivation index on breast cancer survival in the United States
Published in Breast cancer research and treatment (01-11-2023)“…Purpose To analyze the association between the Neighborhood Deprivation Index (NDI) and clinical outcomes of locoregional breast cancer (BC). Methods…”
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2
Transcontinental phylogeography of the Daphnia pulex species complex
Published in PloS one (03-10-2012)“…Daphnia pulex is quickly becoming an attractive model species in the field of ecological genomics due to the recent release of its complete genome sequence, a…”
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3
Facilitates Chromatin Transcription Complex Is an “Accelerator” of Tumor Transformation and Potential Marker and Target of Aggressive Cancers
Published in Cell reports (Cambridge) (11-07-2013)“…The facilitates chromatin transcription (FACT) complex is involved in chromatin remodeling during transcription, replication, and DNA repair. FACT was…”
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4
Racial differences in CD8+ T cell infiltration in breast tumors from Black and White women
Published in Breast cancer research : BCR (09-06-2020)“…Abstract Background African American/Black women with breast cancer have poorer survival than White women, and this disparity persists even after adjusting for…”
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5
CD163 + macrophages in the triple-negative breast tumor microenvironment are associated with improved survival in the Women's Circle of Health Study and the Women's Circle of Health Follow-Up Study
Published in Breast cancer research : BCR (08-05-2024)“…Tumor-associated macrophages (TAMs) are a prominent immune subpopulation in the tumor microenvironment that could potentially serve as therapeutic targets for…”
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6
Identification of a Subset of Stage I Colorectal Cancer Patients With High Recurrence Risk
Published in JNCI : Journal of the National Cancer Institute (09-05-2022)“…Abstract Background A challenge in early-stage colorectal cancer (CRC) is identifying biomarkers that predict an increased risk for recurrence. A potential…”
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7
Multiplexed digital spatial profiling of invasive breast tumors from Black and White women
Published in Molecular oncology (01-01-2022)“…The NanoString GeoMx digital spatial profiling is a new multiplexed platform that quantifies the abundance of tumor‐ and immune‐related proteins in a spatially…”
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8
Smoking, Sex, and Non-Small Cell Lung Cancer: Steroid Hormone Receptors in Tumor Tissue (S0424)
Published in JNCI : Journal of the National Cancer Institute (01-07-2018)“…To what extent steroid hormones contribute to lung cancer in male and female never smokers and smokers is unclear. We examined expression of hormone receptors…”
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9
TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin
Published in Cell cycle (Georgetown, Tex.) (01-08-2012)“…The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. We previously…”
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10
Unbiased Lipidomic Profiling of Triple-Negative Breast Cancer Tissues Reveals the Association of Sphingomyelin Levels with Patient Disease-Free Survival
Published in Metabolites (13-07-2018)“…The reprogramming of lipid metabolism is a hallmark of many cancers that has been shown to promote breast cancer progression. While several lipid signatures…”
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TP53 Status as a Determinant of Pro- vs Anti-Tumorigenic Effects of Estrogen Receptor-Beta in Breast Cancer
Published in JNCI : Journal of the National Cancer Institute (01-11-2019)“…Abstract Background Anti-tumorigenic vs pro-tumorigenic roles of estrogen receptor-beta (ESR2) in breast cancer remain unsettled. We investigated the potential…”
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12
Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer
Published in Proceedings of the National Academy of Sciences - PNAS (11-02-2014)“…Using complete genome analysis, we sequenced five bladder tumors accrued from patients with muscle-invasive transitional cell carcinoma of the urinary bladder…”
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13
Somatic mutations of triple-negative breast cancer: a comparison between Black and White women
Published in Breast cancer research and treatment (01-07-2020)“…Purpose Understanding the contribution of tumor genome biology to racial disparities of triple-negative breast cancer (TNBC) is important for narrowing the…”
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14
Immunohistochemical analysis of adipokine and adipokine receptor expression in the breast tumor microenvironment: associations of lower leptin receptor expression with estrogen receptor-negative status and triple-negative subtype
Published in Breast cancer research : BCR (11-02-2020)“…The molecular mechanisms underlying the association between increased adiposity and aggressive breast cancer phenotypes remain unclear, but likely involve the…”
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15
Analytical Validation of a Next-Generation Sequencing Assay to Monitor Immune Responses in Solid Tumors
Published in The Journal of molecular diagnostics : JMD (01-01-2018)“…We have developed a next-generation sequencing assay to quantify biomarkers of the host immune response in formalin-fixed, paraffin-embedded (FFPE) tumor…”
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16
Epidemiology of Basal-like and Luminal Breast Cancers among Black Women in the AMBER Consortium
Published in Cancer epidemiology, biomarkers & prevention (01-01-2021)“…Evidence suggests etiologic heterogeneity among breast cancer subtypes. Previous studies with six-marker IHC classification of intrinsic subtypes included…”
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Body fatness and breast cancer risk in relation to phosphorylated mTOR expression in a sample of predominately Black women
Published in Breast cancer research : BCR (30-07-2021)“…The mechanistic target of rapamycin (mTOR) pathway promoted by positive energy imbalance and insulin-like growth factors can be a mechanism by which obesity…”
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FOXA1 Protein Expression in ER + and ER - Breast Cancer in Relation to Parity and Breastfeeding in Black and White Women
Published in Cancer epidemiology, biomarkers & prevention (01-02-2020)“…Forkhead box protein A1 (FOXA1) promotes luminal differentiation, and hypermethylation of the gene can be a mechanism of developing estrogen receptor-negative…”
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Robust detection of immune transcripts in FFPE samples using targeted RNA sequencing
Published in Oncotarget (10-01-2017)“…Current criteria for identifying cancer patients suitable for immunotherapy with immune checkpoint blockers (ICBs) are subjective and prone to…”
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Storage Conditions and Immunoreactivity of Breast Cancer Subtyping Markers in Tissue Microarray Sections
Published in Applied immunohistochemistry & molecular morphology (01-04-2020)“…Loss of immunoreactivity in tissue sections has been shown to occur when slide sections are stored at room temperature for prolonged periods of time. We…”
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