Search Results - "Omid Rasool"

Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies by Starskaia, Inna, Valta, Milla, Pietilä, Sami, Suomi, Tomi, Pahkuri, Sirpa, Kalim, Ubaid Ullah, Rasool, Omid, Rydgren, Emilie, Hyöty, Heikki, Knip, Mikael, Veijola, Riitta, Ilonen, Jorma, Toppari, Jorma, Lempainen, Johanna, Elo, Laura L., Lahesmaa, Riitta

“…Previous studies have revealed heterogeneity in the progression to clinical type 1 diabetes in children who develop islet-specific antibodies either to insulin…”
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PIM kinases regulate early human Th17 cell differentiation by Buchacher, Tanja, Shetty, Ankitha, Koskela, Saara A., Smolander, Johannes, Kaukonen, Riina, Sousa, António G.G., Junttila, Sini, Laiho, Asta, Rundquist, Olof, Lönnberg, Tapio, Marson, Alexander, Rasool, Omid, Elo, Laura L., Lahesmaa, Riitta

“…The serine/threonine-specific Moloney murine leukemia virus (PIM) kinase family (i.e., PIM1, PIM2, and PIM3) has been extensively studied in tumorigenesis. PIM…”
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High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity by Borghese, Lodovica, Baker, Duncan, Närvä, Elisa, Harrison, Neil, Kitsberg, Danny, Cui, Wei, Maltby, Edna, Autio, Reija, Itskovitz-Eldor, Joseph, Hovatta, Outi, Benvenisty, Nissim, Kong, Lingjia, Rasool, Omid, Tuuri, Timo, Brüstle, Oliver, Dvorak, Petr, Rahkonen, Nelly, Andrews, Peter W, Lahesmaa, Riitta, Yli-Harja, Olli, Otonkoski, Timo, Moore, Harry D

“…Cultured human embryonic stem cells often acquire chromosomal abnormalities that could be detrimental in certain applications. Närvä et al . report the…”
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Long Intergenic Noncoding RNA MIAT as a Regulator of Human Th17 Cell Differentiation by Khan, Mohd Moin, Khan, Meraj Hasan, Kalim, Ubaid Ullah, Khan, Sofia, Junttila, Sini, Paulin, Niklas, Kong, Lingjia, Rasool, Omid, Elo, Laura L., Lahesmaa, Riitta

“…T helper 17 (Th17) cells protect against fungal and bacterial infections and are implicated in autoimmunity. Several long intergenic noncoding RNAs (lincRNA)…”
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Gut-adipose tissue axis in hepatic fat accumulation in humans by Munukka, Eveliina, Pekkala, Satu, Wiklund, Petri, Rasool, Omid, Borra, Ronald, Kong, Lingjia, Ojanen, Xiaowei, Cheng, Shu Mei, Roos, Christophe, Tuomela, Soile, Alen, Markku, Lahesmaa, Riitta, Cheng, Sulin

“…Background & Aims Recent evidence suggests that in animals gut microbiota composition (GMC) affects the onset and progression of hepatic fat accumulation. The…”
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Transcriptional Repressor HIC1 Contributes to Suppressive Function of Human Induced Regulatory T Cells by Ubaid Ullah, Andrabi, Syed Bilal Ahmad, Tripathi, Subhash Kumar, Dirasantha, Obaiah, Kanduri, Kartiek, Rautio, Sini, Gross, Catharina C., Lehtimäki, Sari, Bala, Kanchan, Tuomisto, Johanna, Bhatia, Urvashi, Chakroborty, Deepankar, Elo, Laura L., Lähdesmäki, Harri, Wiendl, Heinz, Rasool, Omid, Lahesmaa, Riitta

“…Regulatory T (Treg) cells are critical in regulating the immune response. In vitro induced Treg (iTreg) cells have significant potential in clinical medicine…”
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Genome-wide Profiling of Interleukin-4 and STAT6 Transcription Factor Regulation of Human Th2 Cell Programming by Elo, Laura L., Järvenpää, Henna, Tuomela, Soile, Raghav, Sunil, Ahlfors, Helena, Laurila, Kirsti, Gupta, Bhawna, Lund, Riikka J., Tahvanainen, Johanna, Hawkins, R. David, Orešič, Matej, Lähdesmäki, Harri, Rasool, Omid, Rao, Kanury V., Aittokallio, Tero, Lahesmaa, Riitta

“…Dissecting the molecular mechanisms by which T helper (Th) cells differentiate to effector Th2 cells is important for understanding the pathogenesis of…”
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Permutation-based significance analysis reduces the type 1 error rate in bisulphite sequencing data analysis of human umbilical cord blood samples by Laajala, Essi, Halla-aho, Viivi, Grönroos, Toni, Kalim, Ubaid Ullah, Vähä-Mäkilä, Mari, Nurmio, Mirja, Kallionpää, Henna, Lietzén, Niina, Mykkänen, Juha, Rasool, Omid, Toppari, Jorma, Orešič, Matej, Knip, Mikael, Lund, Riikka, Lahesmaa, Riitta, Lähdesmäki, Harri

“…DNA methylation patterns are largely established in-utero and might mediate the impacts of in-utero conditions on later health outcomes. Associations between…”
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The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells by Andersen, Liisa, Gülich, Alexandra Franziska, Alteneder, Marlis, Preglej, Teresa, Orola, Maria Jonah, Dhele, Narendra, Stolz, Valentina, Schebesta, Alexandra, Hamminger, Patricia, Hladik, Anastasiya, Floess, Stefan, Krausgruber, Thomas, Faux, Thomas, Andrabi, Syed Bilal Ahmad, Huehn, Jochen, Knapp, Sylvia, Sparwasser, Tim, Bock, Christoph, Laiho, Asta, Elo, Laura L., Rasool, Omid, Lahesmaa, Riitta, Sakaguchi, Shinya, Ellmeier, Wilfried

“…Forkhead box protein P3+ (FOXP3+) regulatory T cells (Treg cells) play a key role in maintaining tolerance and immune homeostasis. Here, we report that a T…”
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Comparative analysis of human and mouse transcriptomes of Th17 cell priming by Tuomela, Soile, Rautio, Sini, Ahlfors, Helena, Öling, Viveka, Salo, Verna, Ullah, Ubaid, Chen, Zhi, Hämälistö, Saara, Tripathi, Subhash K, Äijö, Tarmo, Rasool, Omid, Soueidan, Hayssam, Wessels, Lodewyk, Stockinger, Brigitta, Lähdesmäki, Harri, Lahesmaa, Riitta

“…Uncontrolled Th17 cell activity is associated with cancer and autoimmune and inflammatory diseases. To validate the potential relevance of mouse models of…”
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Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells by Shetty, Ankitha, Bhosale, Santosh D, Tripathi, Subhash Kumar, Buchacher, Tanja, Biradar, Rahul, Rasool, Omid, Moulder, Robert, Galande, Sanjeev, Lahesmaa, Riitta

“…Dysregulated function of Th17 cells has implications in immunodeficiencies and autoimmune disorders. Th17 cell differentiation is orchestrated by a complex…”
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The regulation and role of c-FLIP in human Th cell differentiation by Kyläniemi, Minna K, Kaukonen, Riina, Myllyviita, Johanna, Rasool, Omid, Lahesmaa, Riitta

“…The early differentiation of T helper (Th) cells is a tightly controlled and finely balanced process, which involves several factors including cytokines,…”
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Quantitative Proteomics Reveals the Dynamic Protein Landscape during Initiation of Human Th17 Cell Polarization by Tripathi, Subhash K., Välikangas, Tommi, Shetty, Ankitha, Khan, Mohd Moin, Moulder, Robert, Bhosale, Santosh D., Komsi, Elina, Salo, Verna, De Albuquerque, Rafael Sales, Rasool, Omid, Galande, Sanjeev, Elo, Laura L., Lahesmaa, Riitta

“…Th17 cells contribute to the pathogenesis of inflammatory and autoimmune diseases and cancer. To reveal the Th17 cell-specific proteomic signature regulating…”
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CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling by Khan, Mohd Moin, Ullah, Ubaid, Khan, Meraj H., Kong, Lingjia, Moulder, Robert, Välikangas, Tommi, Bhosale, Santosh Dilip, Komsi, Elina, Rasool, Omid, Chen, Zhi, Elo, Laura L., Westermarck, Jukka, Lahesmaa, Riitta

“…Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) is an oncogene and a potential cancer therapy target protein. Accordingly, a better understanding of the…”
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Genome-Wide Identification of Novel Genes Involved in Early Th1 and Th2 Cell Differentiation by Lund, Riikka J, Loytomaki, Maritta, Naumanen, Tiina, Dixon, Craig, Chen, Zhi, Ahlfors, Helena, Tuomela, Soile, Tahvanainen, Johanna, Scheinin, Joonas, Henttinen, Tiina, Rasool, Omid, Lahesmaa, Riitta

“…Th cell subtypes, Th1 and Th2, are involved in the pathogenesis or progression of many immune-mediated diseases, such as type 1 diabetes and asthma,…”
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Activating transcription factor 3 is a positive regulator of human IFNG gene expression by Filén, Sanna, Ylikoski, Emmi, Tripathi, Subhash, West, Anne, Björkman, Mari, Nyström, Joel, Ahlfors, Helena, Coffey, Eleanor, Rao, Kanury V S, Rasool, Omid, Lahesmaa, Riitta

“…IL-12 and IL-18 are essential for Th1 differentiation, whereas the role of IFN-alpha in Th1 development is less understood. In this microarray-based study, we…”
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RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA+ and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells by Lund, Riikka J., Rahkonen, Nelly, Malonzo, Maia, Kauko, Leni, Emani, Maheswara Reddy, Kivinen, Virpi, Närvä, Elisa, Kemppainen, Esko, Laiho, Asta, Skottman, Heli, Hovatta, Outi, Rasool, Omid, Nykter, Matti, Lähdesmäki, Harri, Lahesmaa, Riitta

“…POLR3G is expressed at high levels in human pluripotent stem cells (hPSCs) and is required for maintenance of stem cell state through mechanisms not known in…”
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Quantitative Proteomics Reveals GIMAP Family Proteins 1 and 4 to Be Differentially Regulated during Human T Helper Cell Differentiation by Fileén, Jan-Jonas, Fileén, Sanna, Moulder, Robert, Tuomela, Soile, Ahlfors, Helena, West, Anne, Kouvonen, Petri, Kantola, Suvi, Bjoürkman, Mari, Katajamaa, Mikko, Rasool, Omid, Nyman, Tuula A., Lahesmaa, Riitta

“…T helper (Th) cells differentiate into functionally distinct effector cell subsets of which Th1 and Th2 cells are best characterized. Besides T cell receptor…”
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Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia by Liu, Y, Corcoran, M, Rasool, O, Ivanova, G, Ibbotson, R, Grandér, D, Iyengar, A, Baranova, A, Kashuba, V, Merup, M, Wu, X, Gardiner, A, Mullenbach, R, Poltaraus, A, Hultström, A L, Juliusson, G, Chapman, R, Tiller, M, Cotter, F, Gahrton, G, Yankovsky, N, Zabarovsky, E, Einhorn, S, Oscier, D

“…Previous studies have indicated the presence of a putative tumor suppressor gene on chromosome 13q14, commonly deleted in patients with B-cell chronic…”
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6q deletions in acute lymphoblastic leukemia and non-Hodgkin's lymphomas by MERUP, M, MORENO, T. C, G, GAHRTON, S, EINHORN, S, HEYMAN, M, RÖNNBERG, K, GRANDER, D, DETLOFSSON, R, RASOOL, O, YIE LIU, SÖDERHÄLL, S, JULIUSSON, G

“…Deletions on the long arm of chromosome 6 are frequently found in acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphomas (NHL). We have used polymerase…”
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