Search Results - "Omay, Zeynep Erson"
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Exome sequencing identifies SLIT2 variants in primary CNS lymphoma
Published in British journal of haematology (01-04-2021)“…Summary SLIT2 constitutes a known tumour suppressor gene, which has not yet been implicated in the pathogenesis of primary central nervous system lymphoma…”
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Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas
Published in Nature genetics (01-10-2016)“…Murat Günel and colleagues identify recurrent mutations in POLR2A , which encodes the catalytic subunit of RNA polymerase II, in a subset of meningiomas. They…”
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Integrated genomic characterization of IDH1-mutant glioma malignant progression
Published in Nature genetics (01-01-2016)“…Murat Günel and colleagues use an integrated genomic approach to analyze the malignant progression of IDH1 -mutant gliomas. They observe nonlinear clonal…”
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4
Associations of meningioma molecular subgroup and tumor recurrence
Published in Neuro-oncology (Charlottesville, Va.) (05-05-2021)“…Abstract Background We and others have identified mutually exclusive molecular subgroups of meningiomas; however, the implications of this classification for…”
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Integrated genomic analyses of de novo pathways underlying atypical meningiomas
Published in Nature communications (14-02-2017)“…Meningiomas are mostly benign brain tumours, with a potential for becoming atypical or malignant. On the basis of comprehensive genomic, transcriptomic and…”
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A quantitative model based on clinically relevant MRI features differentiates lower grade gliomas and glioblastoma
Published in European radiology (01-06-2020)“…Objectives To establish a quantitative MR model that uses clinically relevant features of tumor location and tumor volume to differentiate lower grade glioma…”
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The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications
Published in Journal of neuro-oncology (2022)“…Introduction Meningiomas are generally considered “benign,” however, these tumors can demonstrate variability in behavior and a surprising aggressiveness with…”
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PPIL4 is essential for brain angiogenesis and implicated in intracranial aneurysms in humans
Published in Nature medicine (01-12-2021)“…Intracranial aneurysm (IA) rupture leads to subarachnoid hemorrhage, a sudden-onset disease that often causes death or severe disability. Although genome-wide…”
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Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma
Published in Molecular genetics & genomic medicine (01-02-2021)“…Background Pilomyxoid astrocytomas are an aggressive subtype of astrocytoma, not graded by WHO, frequently located in hypothalamic/chiasmatic region, affecting…”
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Hypermutated phenotype in gliosarcoma of the spinal cord
Published in NPJ precision oncology (12-02-2021)“…Gliosarcoma is a variant of glioblastoma with equally poor prognosis and characterized by mixed glial and mesenchymal pathology. Metastasis is not uncommon but…”
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Novel EWSR1-VGLL1 fusion in a pediatric neuroepithelial neoplasm
Published in Clinical genetics (01-05-2020)Get full text
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12
Application of novel PACS-based informatics platform to identify imaging based predictors of CDKN2A allelic status in glioblastomas
Published in Scientific reports (22-12-2023)“…Gliomas with CDKN2A mutations are known to have worse prognosis but imaging features of these gliomas are unknown. Our goal is to identify CDKN2A specific…”
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Correction to: A quantitative model based on clinically relevant MRI features differentiates lower grade gliomas and glioblastoma
Published in European radiology (01-07-2020)“…The original version of this article, published on 05 February 2020, unfortunately contained a mistake…”
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Thrombocyte-derived Dickkopf1 promotes macrophage polarization in the Bleomycin-induced lung injury model
Published in Frontiers in immunology (2023)“…Immune responses are crucial to maintaining tissue homeostasis upon tissue injury. Upon various types of challenges, macrophages play a central role in…”
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Exome analysis of the evolutionary path of hepatocellular adenoma-carcinoma transition, vascular invasion and brain dissemination
Published in Journal of hepatology (01-07-2017)“…Summary Hepatocellular adenoma (HCA) is a rare benign liver tumor, predominantly seen in young women. Its major complications are malignant transformation,…”
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Comprehensive Genomic Characterization of A Case of Granular Cell Tumor of the Posterior Pituitary Gland: A Case Report
Published in Frontiers in endocrinology (Lausanne) (01-12-2021)“…Granular cell tumors of the pituitary belong to a rare family of neoplasms, arising from the posterior pituitary gland. Although considered benign, they may…”
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A Quantitative Assessment of Pre-Operative MRI Reports in Glioma Patients: Report Metrics and IDH Prediction Ability
Published in Frontiers in oncology (29-01-2021)“…To measure the metrics of glioma pre-operative MRI reports and build IDH prediction models. Pre-operative MRI reports of 144 glioma patients in a single…”
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NGLY1 mutation causes neuromotor impairment, intellectual disability, and neuropathy
Published in European journal of medical genetics (01-01-2015)“…Abstract N-glycanase 1 ( NGLY1 ) is a conserved enzyme that is responsible for the deglycosylation of misfolded N-glycosylated proteins in the cytoplasm prior…”
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Genomic profiling of sporadic multiple meningiomas
Published in BMC medical genomics (14-05-2022)“…Multiple meningiomas (MMs) rarely occur sporadically. It is unclear whether each individual tumor in a single patient behaves similarly. Moreover, the…”
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Correction: Genomic profiling of sporadic multiple meningiomas
Published in BMC medical genomics (13-06-2022)Get full text
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