Search Results - "Omar, Mohd Feroz"

The Warburg effect and drug resistance by Bhattacharya, Bhaskar, Mohd Omar, Mohd Feroz, Soong, Richie

“…The Warburg effect describes the increased utilization of glycolysis rather than oxidative phosphorylation by tumour cells for their energy requirements under…”
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Methodological aspects of whole-genome bisulfite sequencing analysis by Adusumalli, Swarnaseetha, Mohd Omar, Mohd Feroz, Soong, Richie, Benoukraf, Touati

“…The combination of DNA bisulfite treatment with high-throughput sequencing technologies has enabled investigation of genome-wide DNA methylation beyond CpG…”
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Acquired resistance to PI3K/mTOR inhibition is associated with mitochondrial DNA mutation and glycolysis by Koh, King Xin, Tan, Gim Hwa, Hui Low, Sarah Hong, Mohd Omar, Mohd Feroz, Han, Min Ji, Iacopetta, Barry, Soo, Ross, Beloueche-Babari, Mounia, Bhattacharya, Bhaskar, Soong, Richie

“…Acquired resistance (AQR) to drug treatment occurs frequently in cancer patients and remains an impediment to successful therapy. The aim of this study was to…”
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Determinants of variability of five programmed death ligand-1 immunohistochemistry assays in non-small cell lung cancer samples by Soo, Ross A, Yun Lim, Joey Sze, Asuncion, Bernadette Reyna, Fazreen, Zul, Herrera, Maria Cynthia, Mohd Omar, Mohd Feroz, Diem Phuong, Nguyen Hoang, Seet, Ju Ee, Amanuel, Benhur, Iacopetta, Barry, Byrne, David, Hendry, Shona, Fox, Stephen, Soong, Richie

“…Programmed death ligand-1 (PD-L1) expression as determined by immunohistochemistry (IHC) is potentially predictive of clinical outcome. The aim of this study…”
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Characterization of Numb expression in astrocytomas by Yan, Benedict, Omar, Feroz Mohd, Das, Kakoli, Ng, Wai Hoe, Lim, Chinghway, Shiuan, Koh, Yap, Celestial T., Salto-Tellez, Manuel

“…During early neurodevelopment, asymmetric segregation of Numb in mitotic progenitor cells influences the fate of daughter cells, whereby one daughter retains…”
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Lack of RUNX3 inactivation in columnar cell lesions of breast by Subramaniam, Manish Mani, Chan, Jason Yongsheng, Omar, Mohd Feroz Mohd, Ito, Kosei, Ito, Yoshiaki, Yeoh, Khay Guan, Salto-Tellez, Manuel, Putti, Thomas Choudary

“…Subramaniam M M, Chan J Y, Omar M F M, Ito K, Ito Y, Yeoh K G, Salto‐Tellez M & Putti T C
(2010) Histopathology57, 555–563
Lack of RUNX3 inactivation in…”
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Molecular-assisted immunohistochemical optimization by Mohd Omar, Mohd Feroz, Huang, Ning, Ou, Keli, Yu, Kun, Putti, Thomas C., Jikuya, Hiroyuki, Ichikawa, Tetsuo, Nishimura, Osamu, Tan, Patrick, Salto-Tellez, Manuel

“…Immunohistochemistry (IHC) is an essential tool in diagnostic surgical pathology, allowing analysis of protein subcellular localization. The use of IHC by…”
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TRARESA: a tissue microarray-based hospital system for biomarker validation and discovery by Das, Kakoli, Mohd Omar, Mohd Feroz, Ong, Chee Wee, Abdul Rashid, Suhaimi Bin, Peh, Bee Keow, Putti, Thomas Choudary, Tan, Puay Hoon, Chia, Kee Seng, Teh, Ming, Shah, Nilesh, Soong, Richie, Salto-Tellez, Manuel

“…Formalin fixed and paraffin embedded tissue (FFPE) collections in pathology departments are the largest resource for retrospective biomedical research studies…”
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Integrated molecular analysis of Asian ovarian cancer: Gene expression and whole exome sequencing analyses from the iPocc Translational Research study (TriPocc) by Huang, Ruby, Tan, Tuan Zea, Ye, Jieru, Kuschal, Christiane, Mok, Zuan Yu, Goh, Shane Ee, Tan, Sili, Tay, Jia Xian, Mohd Omar, Mohd Feroz, Sato, Sho, Jeyasekharan, Anand Devaprasath, Lim, Diana, Soong, Richie Chuan Teck, Fujiwara, Keiichi, Hasegawa, Kosei, Tan, David Shao Peng

“…Abstract only…”
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Whole Exome Sequencing of Multi-Regional Biopsies from Metastatic Lesions to Evaluate Actionable Truncal Mutations Using a Single-Pass Percutaneous Technique by Heong, Valerie, Tay, Darwin, Goh, Shane Ee, Wee, Bernard, Tan, Tuan Zea, Soo, Ross, Pang, Brendan, Lim, Diana, Gopinathan, Anil, Ow, Samuel, Chee, Cheng Ean, Goh, Boon Cher, Lee, Soo Chin, Yong, Wei Peng, Wong, Andrea, Omar, Mohamed Feroz Mohd, Soong, Richie, Tan, David SP

“…We investigate the feasibility of obtaining multiple spatially-separated biopsies from a single lesion to explore intratumor heterogeneity and identify…”
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Abstract 165: A novel in vitro microenvironment modeling platform for HCC therapeutics and biomarker development by Omar, Mohd Feroz Mohd, Tang, Benny, Chang, Sheng Chun, Low, Sarah Hong Hui, Tan, Gim Hwa, Soong, Richie, Bhattacharya, Bhaskar

“…Abstract Background: Hepatocellular carcinoma (HCC) is characterized by hypoxia, hypoglycemia and lactic acidosis within the microenvironment due a highly…”
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Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells by Bhattacharya, Bhaskar, Huang, Daniel Q, Low, Sarah Hong Hui, Tan, Gim Hwa, Han, Min Ji, Singh, Sanamerjit, Tang, Benny, Chang, Sheng Chun, Lim, Joey Sze Yun, Omar, Mohd Feroz Mohd, Dan, Yock Young, Soong, Richie

“…The native hepatocellular cancer (HCC) microenvironment is characterized by more hypoxic, hypoglycemic, and acidic conditions than those used in standard cell…”
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Significance of immune checkpoint proteins in EGFR -mutant non-small cell lung cancer by Soo, Ross A, Kim, Hye Ryun, Asuncion, Bernadette Reyna, Fazreen, Zul, Omar, Mohamed Feroz Mohd, Herrera, Maria Cynthia, Yun Lim, Joey Sze, Sia, Grace, Soong, Richie, Cho, Byoung-Chul

“…Highlights • Casesof advanced stage EGFR mutant NSCLC were analysed. • PD-L1, PD-1, CTLA-4 and TIM3 expression were characterized. • High tumor PD-L1 had a…”
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RUNX3 Downregulation in Human Lung Adenocarcinoma is Independent of p53, EGFR or KRAS Status by Omar, Mohd Feroz Mohd, Ito, Kosei, Nga, Min En, Soo, Ross, Peh, Bee Keow, Ismail, Tuty Muliana, Thakkar, Bhavin, Soong, Richie, Ito, Yoshiaki, Salto-Tellez, Manuel

“…RUNX3 aberrations play a pivotal role in the oncogenesis of breast, gastric, colon, skin and lung tissues. The aim of this study was to characterize further…”
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Cofilin immunolabelling correlates with depth of invasion in gastrointestinal endocrine cell tumors by Yan, Benedict, Yap, Celestial T., Wang, Shi, Lee, Chi Kuen, Koh, Shiuan, Omar, Mohd Feroz, Salto-Tellez, Manuel, Kumarasinghe, Marian Priyanthi

“…Gastrointestinal endocrine cell tumors are a heterogeneous population of lesions believed to arise from neuroendocrine cells of the gastrointestinal mucosa…”
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