Search Results - "Omaque, Neil"

Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity by Myers, Darienne R, Abram, Clare L, Wildes, David, Belwafa, Amira, Welsh, Alia M N, Schulze, Christopher J, Choy, Tiffany J, Nguyen, Tram, Omaque, Neil, Hu, Yongmei, Singh, Mallika, Hansen, Rich, Goldsmith, Mark A, Quintana, Elsa, Smith, Jacqueline A M, Lowell, Clifford A

“…Shp1, encoded by the gene , is a protein tyrosine phosphatase that transduces inhibitory signals downstream of immunoreceptors in many immune cell types…”
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Abstract 2837: Dual inhibition of SHP2 and CDK4/6 leads to immunological memory and immune-mediated anti-tumor activity in a mouse syngeneic model of breast cancer by Shifrin, Nataliya Tovbis, Lee, Grace J., Omaque, Neil, Nguyen, Tram, Belwafa, Amira, Lorenzana, Edward G., Nichols, Robert J., Smith, Jacqueline A., Singh, Mallika, Quintana, Elsa

“…Abstract Allosteric inhibition of the phosphatase SHP2, a key signaling node in the RAS pathway, is a novel, investigational therapeutic strategy for patients…”
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