Search Results - "Olsthoorn, Rene C. L"

In Vitro and In Vivo Studies of the RNA Conformational Switch in Alfalfa Mosaic Virus by CHEN, Shih-Cheng, OLSTHOORN, René C. L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An RNA conformational shift in recent H5N1 influenza A viruses by Gultyaev, Alexander P., Heus, Hans A., Olsthoorn, René C. L.

“…Recent outbreaks of avian influenza are being caused by unusually virulent H5N1 strains. It is unknown what makes these recent H5N1 strains more aggressive…”
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Application of Coiled Coil Peptides in Liposomal Anticancer Drug Delivery Using a Zebrafish Xenograft Model by Yang, Jian, Shimada, Yasuhito, Olsthoorn, René C. L, Snaar-Jagalska, B. Ewa, Spaink, Herman P, Kros, Alexander

“…The complementary coiled coil forming peptides E4 [(EIAALEK)4] and K4 [(KIAALKE)4] are known to trigger liposomal membrane fusion when tethered to lipid…”
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Xrn1-resistant RNA motifs are disseminated throughout the RNA virome and are able to block scanning ribosomes by Dilweg, Ivar W., Peer, Jasper, Olsthoorn, René C. L.

“…RNAs that are able to prevent degradation by the 5’–3’ exoribonuclease Xrn1 have emerged as crucial structures during infection by an increasing number of RNA…”
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Role of an RNA pseudoknot involving the polyA tail in replication of Pepino mosaic potexvirus and related plant viruses by Olsthoorn, René C. L., Owen, Carolyn A., Livieratos, Ioannis C.

“…Pepino mosaic virus (PepMV) is a potexvirus of the family Alphaflexiviridae within the order of Tymovirales that threatens tomato production worldwide. PepMV…”
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Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes by Yang, Jian, Bahreman, Azadeh, Daudey, Geert, Bussmann, Jeroen, Olsthoorn, René C. L, Kros, Alexander

“…Efficient delivery of drugs to living cells is still a major challenge. Currently, most methods rely on the endocytotic pathway resulting in low delivery…”
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Group-specific structural features of the 5′-proximal sequences of coronavirus genomic RNAs by Chen, Shih-Cheng, Olsthoorn, René C.L

“…Abstract Global predictions of the secondary structure of coronavirus (CoV) 5′ untranslated regions and adjacent coding sequences revealed the presence of…”
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Stimulation of ribosomal frameshifting by RNA G-quadruplex structures by Yu, Chien-Hung, Teulade-Fichou, Marie-Paule, Olsthoorn, René C L

“…Guanine-rich sequences can fold into four-stranded structures of stacked guanine-tetrads, so-called G-quadruplexes (G4). These unique motifs have been…”
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Tospovirus ambisense genomic RNA segments use almost complete repertoire of stable tetraloops in the intergenic region by Clabbers, Max T B, Olsthoorn, Rene C L, Gultyaev, Alexander P

“…The intergenic regions of the ambisense RNA segments of viruses from the Tospovirus genus form large extended RNA structures that regulate virus replication…”
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Membrane Fusion Mediated Intracellular Delivery of Lipid Bilayer Coated Mesoporous Silica Nanoparticles by Yang, Jian, Tu, Jing, Lamers, Gerda E. M., Olsthoorn, René C. L., Kros, Alexander

“…Protein delivery into the cytosol of cells is a challenging topic in the field of nanomedicine, because cellular uptake and endosomal escape are typically…”
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Influenza Virus RNA Structure: Unique and Common Features by Gultyaev, Alexander P., Fouchier, Ron A. M., Olsthoorn, René C. L.

“…The influenza A virus genome consists of eight negative-sense RNA segments. Here we review the currently available data on structure-function relationships in…”
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Megalencephalic leukoencephalopathy with subcortical cysts: a variant update and review of the literature by Passchier, Emma M J, Bisseling, Quinty, Helman, Guy, van Spaendonk, Rosalina M L, Simons, Cas, Olsthoorn, René C L, van der Veen, Hieke, Abbink, Truus E M, van der Knaap, Marjo S, Min, Rogier

“…The leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts (MLC) is characterized by infantile-onset macrocephaly and chronic edema of the…”
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Performing DNA nanotechnology operations on a zebrafish by Yang, Jian, Meng, Zhuojun, Liu, Qing, Shimada, Yasuhito, Olsthoorn, René C L, Spaink, Herman P, Herrmann, Andreas, Kros, Alexander

“…Nanoscale engineering of surfaces is becoming an indispensable technique to modify membranes and, thus cellular behaviour. Here, such membrane engineering…”
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Subtype-specific structural constraints in the evolution of influenza A virus hemagglutinin genes by Gultyaev, Alexander P., Spronken, Monique I., Richard, Mathilde, Schrauwen, Eefje J. A., Olsthoorn, René C. L., Fouchier, Ron A. M.

“…The influenza A virus genome consists of eight RNA segments. RNA structures within these segments and complementary (cRNA) and protein-coding mRNAs may play a…”
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The subgenomic promoter of brome mosaic virus folds into a stem-loop structure capped by a pseudo-triloop that is structurally similar to the triloop of the genomic promoter by Skov, Joan, Gaudin, Mathieu, Podbevsek, Peter, Olsthoorn, René C L, Petersen, Michael

“…In brome mosaic virus, both the replication of the genomic (+)-RNA strands and the transcription of the subgenomic RNA are carried out by the viral replicase…”
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Design of a Ribosyltriazole-Annulated Cyclooctyne for Oligonucleotide Labeling by Strain-Promoted Alkyne-Azide Cycloaddition by van Delft, Pieter, de Witte, Wilbert, Meeuwenoord, Nico J., van der Heden van Noort, Gerbrand J., Versluis, Frank, Olsthoorn, Rene C. L., Overkleeft, Herman S., van der Marel, Gijs A., Filippov, Dmitri V.

“…A ribosyltriazole ring‐fused cyclooctyne was prepared and converted into the corresponding phosphoramidite, which was applied in the automated synthesis of DNA…”
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A database of flavivirus RNA structures with a search algorithm for pseudoknots and triple base interactions by Zammit, Alan, Helwerda, Leon, Olsthoorn, René C L, Verbeek, Fons J, Gultyaev, Alexander P

“…Abstract Motivation The Flavivirus genus includes several important pathogens, such as Zika, dengue and yellow fever virus. Flavivirus RNA genomes contain a…”
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Relevance of the iron-responsive element (IRE) pseudotriloop structure for IRP1/2 binding and validation of IRE-like structures using the yeast three-hybrid system by Chen, Shih-Cheng, Olsthoorn, René C.L.

“…Iron-responsive elements (IREs) are ~35-nucleotide (nt) stem-loop RNA structures located in 5′ or 3′ untranslated regions (UTRs) of mRNAs that mediate…”
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Magnetic-Activated Cell Sorting Using Coiled-Coil Peptides: An Alternative Strategy for Isolating Cells with High Efficiency and Specificity by Shen, Meng-Jie, Olsthoorn, René C.L, Zeng, Ye, Bakkum, Thomas, Kros, Alexander, Boyle, Aimee L

“…Magnetic-activated cell sorting (MACS) is an affinity-based technique used to separate cells according to the presence of specific markers. Current MACS…”
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G-quadruplexes within prion mRNA: the missing link in prion disease? by Olsthoorn, René C L

“…Cellular ribonucleic acid (RNA) plays a crucial role in the initial conversion of cellular prion protein PrP(C) to infectious PrP(Sc) or scrapie. The nature of…”
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