Search Results - "Olstad, Ole K"

Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women by Reppe, Sjur, Lien, Tonje G., Hsu, Yi-Hsiang, Gautvik, Vigdis T., Olstad, Ole K., Yu, Rona, Bakke, Hege G., Lyle, Robert, Kringen, Marianne K., Glad, Ingrid K., Gautvik, Kaare M.

“…DNA methylation affects expression of associated genes and may contribute to the missing genetic effects from genome-wide association studies of osteoporosis…”
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Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis by Datta, Harish K, Kringen, Marianne K, Tuck, Stephen P, Salpingidou, Georgia, Olstad, Ole K, Gautvik, Kaare M, Cockell, Simon J, Gautvik, Vigdis T, Prediger, Michael, Wu, Jun Jie, Birch, Mark A, Reppe, Sjur

“…Mechanical loading exerts a profound influence on bone density and architecture, but the exact mechanism is unknown. Our study shows that expression of the…”
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Molecular disease map of bone characterizing the postmenopausal osteoporosis phenotype by Jemtland, Rune, Holden, Marit, Reppe, Sjur, Olstad, Ole K, Reinholt, Finn P, Gautvik, Vigdis T, Refvem, Hilde, Frigessi, Arnoldo, Houston, Brian, Gautvik, Kaare M

“…Genome‐wide gene expressions in bone biopsies from patients with postmenopausal osteoporosis and healthy controls were profiled, to identify osteoporosis…”
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The acute phase response protein SERPINA3 is increased in tear fluid from the unaffected eyes of patients with unilateral acute anterior uveitis by Eidet, Jon Roger, Akopian, Maja, Olstad, Ole K., Jørstad, Øystein Kalsnes, Moe, Morten C., Petrovski, Goran, Pepaj, Milaim

“…Background To identify candidate tear fluid biomarkers in patients with unilateral acute anterior uveitis (AAU) that can aid in the differentiation between…”
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Transcriptional profiling of mRNAs and microRNAs in human bone marrow precursor B cells identifies subset- and age-specific variations by Jensen, Kristin, Brusletto, Berit Sletbakk, Aass, Hans Christian Dalsbotten, Olstad, Ole K, Kierulf, Peter, Gautvik, Kaare M

“…Molecular mechanisms explaining age-related changes in the bone marrow with reduced precursor B cell output are poorly understood. We studied the transcriptome…”
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Unilateral acute anterior uveitis is associated with ipsilateral changes in the tear fluid proteome that involves the LXR/RXR pathway by Eidet, Jon Roger, Jørstad, Øystein Kalsnes, Fostad, Ida G., Olstad, Ole K., Sørland, Ragnhild Ø., Moe, Morten C., Petrovski, Goran, Pepaj, Milaim

“…Purpose To determine whether unilateral acute anterior uveitis (AAU) induces ipsilateral changes in the tear fluid proteome. Methods Five patients (25–77 years…”
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Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes by Utheim, Tor Paaske, Islam, Rakibul, Fostad, Ida G, Eidet, Jon R, Sehic, Amer, Olstad, Ole K, Dartt, Darlene A, Messelt, Edward B, Griffith, May, Pasovic, Lara

“…Storage of cultured human oral keratinocytes (HOK) allows for transportation of cultured transplants to eye clinics worldwide. In a previous study, one-week…”
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In silico discovery of blood cell macromolecular associations by Gautvik, Kaare M, Sachse, Daniel, Hinton, Alexandra C, Olstad, Ole K, Kiel, Douglas P, Hsu, Yi-Hsiang, Utheim, Tor P, Lary, Christine W, Reppe, Sjur

“…Abstract Background Physical molecular interactions are the basis of intracellular signalling and gene regulatory networks, and comprehensive, accessible…”
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Zic1 transcription factor in bone: neural developmental protein regulates mechanotransduction in osteocytes by Kalogeropoulos, Michail, Varanasi, Satya S, Olstad, Ole K, Sanderson, Paul, Gautvik, Vigdis T, Reppe, Sjur, Francis, Roger M, Gautvik, Kaare M, Birch, Mark A, Datta, Harish K

“…A transcriptome analysis compared gene expression in human bone biopsy samples taken from lumbar spine and iliac crest, sites that experience high and low…”
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Skeletal site-related variation in human trabecular bone transcriptome and signaling by Varanasi, Satya S, Olstad, Ole K, Swan, Daniel C, Sanderson, Paul, Gautvik, Vigdis T, Reppe, Sjur, Francis, Roger M, Gautvik, Kaare M, Datta, Harish K

“…The skeletal site-specific influence of multiple genes on bone morphology is recognised, but the question as to how these influences may be exerted at the…”
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Comparison of the Histology, Gene Expression Profile, and Phenotype of Cultured Human Limbal Epithelial Cells from Different Limbal Regions by Utheim, Tor P, Raeder, Sten, Olstad, Ole K, Utheim, Oygunn A, de La Paz, Maria, Cheng, Robert, Huynh, Trang T, Messelt, Edward, Roald, Borghild, Lyberg, Torstein

“…To investigate whether human limbal epithelial cells (HLECs) derived from various regions of the limbus exhibit differences in gene expression and epithelial…”
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Stress associated gene expression in blood cells is related to outcome in radiotherapy treated head and neck cancer patients by Bøhn, Siv K, Russnes, Kjell M, Sakhi, Amrit K, Thoresen, Magne, Holden, Marit, Moskaug, Jan Ø, Myhrstad, Mari C, Olstad, Ole K, Smeland, Sigbjørn, Blomhoff, Rune

“…We previously observed that a radiotherapy-induced biochemical response in plasma was associated with favourable outcome in head and neck squamous carcinoma…”
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Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker by Vilming Elgaaen, Bente, Olstad, Ole Kristoffer, Haug, Kari Bente Foss, Brusletto, Berit, Sandvik, Leiv, Staff, Anne Cathrine, Gautvik, Kaare M, Davidson, Ben

“…Improved insight into the molecular characteristics of the different ovarian cancer subgroups is needed for developing a more individualized and optimized…”
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Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight‐Bearing and Non–Weight‐Bearing Human Bone by Gautvik, Kaare M, Günther, Clara‐Cecilie, Prijatelj, Vid, Medina‐Gomez, Carolina, Shevroja, Enisa, Rad, Leila Heidary, Yazdani, Mazyar, Lindalen, Einar, Valland, Haldor, Gautvik, Vigdis T, Olstad, Ole K, Holden, Marit, Rivadeneira, Fernando, Utheim, Tor P, Reppe, Sjur

“…ABSTRACT We investigated mechanisms resulting in low bone mineral density (BMD) and susceptibility to fracture by comparing noncoding RNAs (ncRNAs) in biopsies…”
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miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial–mesenchymal transition in pterygium by Engelsvold, David H., Utheim, Tor P., Olstad, Ole K., Gonzalez, Pedro, Eidet, Jon R., Lyberg, Torstein, Trøseid, Anne-Marie S., Dartt, Darlene A., Raeder, Sten

“…The current study investigates whether microRNA (miRNA) regulators of epithelial–mesenchymal transition (EMT), tissue fibrosis, and angiogenesis are…”
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Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus by Medina-Gomez, Carolina, Kemp, John P, Estrada, Karol, Eriksson, Joel, Liu, Jeff, Reppe, Sjur, Evans, David M, Heppe, Denise H M, Vandenput, Liesbeth, Herrera, Lizbeth, Ring, Susan M, Kruithof, Claudia J, Timpson, Nicholas J, Zillikens, M Carola, Olstad, Ole K, Zheng, Hou-Feng, Richards, J Brent, St Pourcain, Beate, Hofman, Albert, Jaddoe, Vincent W V, Smith, George Davey, Lorentzon, Mattias, Gautvik, Kaare M, Uitterlinden, André G, Brommage, Robert, Ohlsson, Claes, Tobias, Jonathan H, Rivadeneira, Fernando

“…To identify genetic loci influencing bone accrual, we performed a genome-wide association scan for total-body bone mineral density (TB-BMD) variation in 2,660…”
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Eight genes are highly associated with BMD variation in postmenopausal Caucasian women by Reppe, Sjur, Refvem, Hilde, Gautvik, Vigdis T, Olstad, Ole K, Høvring, Per I, Reinholt, Finn P, Holden, Marit, Frigessi, Arnoldo, Jemtland, Rune, Gautvik, Kaare M

“…Abstract Low bone mineral density (BMD) is an important risk factor for skeletal fractures which occur in about 40% of women ≥ 50 years in the western world…”
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Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs by Ness, Charlotte, Garred, Øystein, Eide, Nils A, Kumar, Theresa, Olstad, Ole K, Bærland, Thomas P, Petrovski, Goran, Moe, Morten C, Noer, Agate

“…Uveal melanoma (UM) has a high propensity for metastatic spread, and approximately 40-50% of patients die of metastatic disease. Metastases can be found at the…”
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The α2β1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: A preclinical study by Rucci, Nadia, Capulli, Mattia, Olstad, Ole K., Önnerfjord, Patrik, Tillgren, Viveka, Gautvik, Kaare M., Heinegård, Dick, Teti, Anna

“…cyclicCHAD is a peptide representing the α2β1 integrin binding sequence of the matrix protein chondroadherin (CHAD), which in our hands proved effective at…”
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The C‐Terminal Domain of Chondroadherin: A New Regulator of Osteoclast Motility Counteracting Bone Loss by Capulli, Mattia, Olstad, Ole K, Önnerfjord, Patrik, Tillgren, Viveka, Muraca, Maurizio, Gautvik, Kaare M, Heinegård, Dick, Rucci, Nadia, Teti, Anna

“…ABSTRACT Chondroadherin (CHAD) is a leucine‐rich protein promoting cell attachment through binding to integrin α2β1 and syndecans. We observed that CHAD mRNA…”
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