Search Results - "Olson, T M"

Aminoglycoside-induced Translational Read-through in Disease: Overcoming Nonsense Mutations by Pharmacogenetic Therapy by Zingman, LV, Park, S, Olson, TM, Alekseev, AE, Terzic, A

“…A third of inherited diseases result from premature termination codon mutations. Aminoglycosides have emerged as vanguard pharmacogenetic agents in treating…”
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Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient‐Derived iPSC Model by Wyles, SP, Hrstka, SC, Reyes, S, Terzic, A, Olson, TM, Nelson, TJ

“…For inherited cardiomyopathies, abnormal sensitivity to intracellular calcium (Ca2+), incurred from genetic mutations, initiates subsequent molecular events…”
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A Common Polymorphism in SCN5A is Associated with Lone Atrial Fibrillation by Chen, LY, Ballew, JD, Herron, KJ, Rodeheffer, RJ, Olson, TM

“…The cardiac sodium channel (SCN5A) is a target for the treatment of arrhythmias. We hypothesized that vulnerability to atrial fibrillation (AF) could be caused…”
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Cardiac troponin T mutation in familial cardiomyopathy with variable remodeling and restrictive physiology by Menon, SC, Michels, VV, Pellikka, PA, Ballew, JD, Karst, ML, Herron, KJ, Nelson, SM, Rodeheffer, RJ, Olson, TM

“…We identified a unique family with autosomal dominant heart disease variably expressed as restrictive cardiomyopathy (RCM), hypertrophic cardiomyopathy (HCM),…”
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Effect of assay specificity on the association of urine 11‐dehydro thromboxane B2 determination with cardiovascular risk by OLSON, M. T., KICKLER, T. S., LAWSON, J. A., MCLEAN, R. C., JANI, J., FITZGERALD, G. A., RADE, J. J.

“…Background: Elevated urine 11‐dehydro TXB2, an indicator of persistent thromboxane generation in aspirin‐treated patients, correlates with adverse…”
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Actin Mutations in Dilated Cardiomyopathy, a Heritable Form of Heart Failure by Olson, Timothy M., Michels, Virginia V., Thibodeau, Stephen N., Tai, Yin-Shan, Keating, Mark T.

“…To test the hypothesis that actin dysfunction leads to heart failure, patients with hereditary idiopathic dilated cardiomyopathy (IDC) were examined for…”
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Progression of familial and non-familial dilated cardiomyopathy: long term follow up by Michels, V V, Driscoll, D J, Miller, F A, Olson, T M, Atkinson, E J, Olswold, C L, Schaid, D J

“…Background: It is unknown whether progression of familial idiopathic dilated cardiomyopathy differs from progression in the non-familial form. It has been…”
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Filtration of Recombinant Norwalk Virus Particles and Bacteriophage MS2 in Quartz Sand:  Importance of Electrostatic Interactions by Redman, J. A, Grant, S. B, Olson, T. M, Hardy, M. E, Estes, M. K

“…Norwalk virus is known to be transmitted through groundwater, yet the environmental factors that facilitate its interstitial transport in subsurface systems…”
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Mapping a cardiomyopathy locus to chromosome 3p22-p25 by Olson, T M, Keating, M T

“…Dilated cardiomyopathy (DCM) is a common disorder characterized by cardiac dilation and reduced systolic function. To identify a cardiomyopathy gene, we…”
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A 30 kb deletion within the elastin gene results in familial supravalvular aortic stenosis by Olson, T M, Michels, V V, Urban, Z, Csiszar, K, Christiano, A M, Driscoll, D J, Feldt, R H, Boyd, C D, Thibodeau, S N

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Transport of humic matter-coated hematite in packed beds by Amirbahman, Aria, Olson, Terese M

“…Column filtration experiments were conducted to study the deposition kinetics of hematite particles in the presence of three well-characterized humic…”
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Carbon Nanotube Based Sensor to Monitor Crack Growth in Cracked Aluminum Structures Underneath Composite Patching by Olson, T. M., Kwon, Y. W., Hart, D. C., Loup, D. C., Rasmussen, E. A.

“…The paper investigates a carbon nanotube-based sensor to detect crack propagation in aluminum structures underneath composite patching. Initial tests are…”
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Physicochemical mechanisms responsible for the filtration and mobilization of a filamentous bacteriophage in quartz sand by Redman, Jeremy A., B. Grant, Stanley, Olson, Terese M., Adkins, Jessica M., Jackson, James L., Castillo, Milagros S., Yanko, William A.

“…This study examines the influence of pore water chemistry on the filtration and physicochemical properties of a male-specific filamentous bacteriophage…”
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Mutations that Alter the Surface Charge of Alpha-tropomyosin are Associated with Dilated Cardiomyopathy by Olson, Timothy M., Kishimoto, Nina Y., Whitby, Frank G., Michels, Virginia V.

“…Proteins in cardiac myocytes assemble into contractile units known as sarcomeres. Contractile force is generated by interaction between sarcomeric thick and…”
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Mechanism and Kinetics of Cyanogen Chloride Formation from the Chlorination of Glycine by Na, Chongzheng, Olson, Terese M

“…Glycine is an important precursor of cyanogen chloride (CNCl)a disinfection byproduct (DBP) found in chlorinated drinking water. To model CNCl formation from…”
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Autosomal dominant supravalvular aortic stenosis: localization to chromosome 7 by Olson, T M, Michels, V V, Lindor, N M, Pastores, G M, Weber, J L, Schaid, D J, Driscoll, D J, Feldt, R H, Thibodeau, S N

“…Supravalvular aortic stenosis (SVAS) is a localized or diffuse congenital narrowing of the ascending aorta which may occur sporadically, as a familial defect,…”
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Inherited and de novo Mutations in the Cardiac Actin Gene Cause Hypertrophic Cardiomyopathy by Olson, Timothy M, Doan, Thao P, Kishimoto, Nina Y, Whitby, Frank G, Ackerman, Michael J, Fananapazir, Lameh

“…T. M. Olson, T. P. Doan, N. Y. Kishimoto, F. G. Whitby, M. J. Ackerman and L. Fananapazir. Inherited andde novo Mutations in the Cardiac Actin Gene Cause…”
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Exclusion of a primary gene defect at the HLA locus in familial idiopathic dilated cardiomyopathy by Olson, T M, Thibodeau, S N, Lundquist, P A, Schaid, D J, Michels, V V

“…Case control studies have reported associations between specific HLA class II antigens and idiopathic dilated cardiomyopathy (DCM), suggesting that genetically…”
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Pathogen Filtration, Heterogeneity, and the Potable Reuse of Wastewater by Redman, Jeremy A, Grant, Stanley B, Olson, Terese M, Estes, Mary K

“…Filtration is commonly employed in water and wastewater treatment to remove particles and reduce the concentration of microbial pathogens. All physical models…”
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Cyanogen Chloride Precursor Analysis in Chlorinated River Water by Lee, Jun Hee, Na, Chongzheng, Ramirez, Roberto L, Olson, Terese M

“…Amino acids have been cited as potential precursors of the disinfection byproduct cyanogen chloride in chlorinated drinking water. Screening experiments with…”
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