Search Results - "Olson, P."
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1
Quantum Chemistry in the Age of Quantum Computing
Published in Chemical reviews (09-10-2019)“…Practical challenges in simulating quantum systems on classical computers have been widely recognized in the quantum physics and quantum chemistry communities…”
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Quantum optical neural networks
Published in npj quantum information (17-07-2019)“…Physically motivated quantum algorithms for specific near-term quantum hardware will likely be the next frontier in quantum information science. Here, we show…”
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Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State
Published in Cell metabolism (05-03-2019)“…Understanding the neural framework behind appetite control is fundamental to developing effective therapies to combat the obesity epidemic. The paraventricular…”
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Liraglutide Modulates Appetite and Body Weight Through Glucagon-Like Peptide 1 Receptor-Expressing Glutamatergic Neurons
Published in Diabetes (New York, N.Y.) (01-08-2018)“…Glucagon-like peptide 1 receptor (GLP-1R) agonists are U.S. Food and Drug Administration-approved weight loss drugs. Despite their widespread use, the sites of…”
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A neural basis for melanocortin-4 receptor–regulated appetite
Published in Nature neuroscience (01-06-2015)“…Melanocortin 4 receptors (MC4Rs) are critical to the promotion of homeostatic satiety. The authors established paraventricular hypothalamus (PVH)…”
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An obligate role of oxytocin neurons in diet induced energy expenditure
Published in PloS one (18-09-2012)“…Oxytocin neurons represent one of the major subsets of neurons in the paraventricular hypothalamus (PVH), a critical brain region for energy homeostasis…”
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Targeting Krasg12c‐mutant cancer with a mutation‐specific inhibitor
Published in Journal of internal medicine (01-08-2020)“…The RAS genes, which include H, N, and KRAS, comprise the most frequently mutated family of oncogenes in cancer. Mutations in KRAS – such as the G12C mutation…”
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The Oral Case Presentation
Published in Journal of general internal medicine : JGIM (01-03-2023)Get full text
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Sex Differences in Cardiac Rehabilitation Outcomes
Published in Circulation research (18-02-2022)“…Cardiovascular disease is a leading cause of morbidity and mortality in males and females in the United States and globally. Cardiac rehabilitation (CR) is…”
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Childhood stress, grown-up brain networks: corticolimbic correlates of threat-related early life stress and adult stress response
Published in Psychological medicine (01-05-2018)“…Exposure to threat-related early life stress (ELS) has been related to vulnerability for stress-related disorders in adulthood, putatively via disrupted…”
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Dopaminergic Enhancement of Striatal Response to Reward in Major Depression
Published in The American journal of psychiatry (01-04-2017)“…Objective:Major depressive disorder is characterized by reduced reward-related striatal activation and dysfunctional reward learning, putatively reflecting…”
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The Role of PVH Circuits in Leptin Action and Energy Balance
Published in Annual review of physiology (01-01-2016)“…Although it has been known for more than a century that the brain controls overall energy balance and adiposity by regulating feeding behavior and energy…”
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Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations
Published in Nature communications (02-09-2020)“…The hypothalamic suprachiasmatic (SCN) clock contains several neurochemically defined cell groups that contribute to the genesis of circadian rhythms. Using…”
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Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony
Published in Neuron (Cambridge, Mass.) (14-10-2020)“…The suprachiasmatic nucleus (SCN) acts as a master pacemaker driving circadian behavior and physiology. Although the SCN is small, it is composed of many cell…”
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GABAergic RIP-Cre Neurons in the Arcuate Nucleus Selectively Regulate Energy Expenditure
Published in Cell (26-10-2012)“…Neural regulation of energy expenditure is incompletely understood. By genetically disrupting GABAergic transmission in a cell-specific fashion, and by…”
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MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus
Published in Proceedings of the National Academy of Sciences - PNAS (09-09-2014)“…Significance Both in rodents and humans, melanocortin-4 receptors (MC4Rs) suppress appetite and prevent obesity. Unfortunately, the underlying neural…”
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Cardiac-Specific Deletion of Acetyl CoA Carboxylase 2 Prevents Metabolic Remodeling During Pressure-Overload Hypertrophy
Published in Circulation research (31-08-2012)“…RATIONALE:Decreased fatty acid oxidation (FAO) with increased reliance on glucose are hallmarks of metabolic remodeling that occurs in pathological cardiac…”
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Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus
Published in The Journal of neuroscience (12-11-2014)“…The paraventricular nucleus of the hypothalamus (PVH) contains a heterogeneous cluster of Sim1-expressing cell types that comprise a major autonomic output…”
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Optimizing Outcomes in Cardiac Rehabilitation: The Importance of Exercise Intensity
Published in Frontiers in cardiovascular medicine (03-09-2021)“…Exercise based cardiac rehabilitation (CR) is recognized internationally as a class 1 clinical practice recommendation for patients with select cardiovascular…”
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Gravitational Dynamos and the Low-Frequency Geomagnetic Secular Variation
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2007)“…Self-sustaining numerical dynamos are used to infer the sources of low-frequency secular variation of the geomagnetic field. Gravitational dynamo models…”
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