Search Results - "Olson, Melissa V"
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Mammary tumor modifiers in BALB/cJ mice heterozygous for p53
Published in Mammalian genome (01-05-2007)“…BALB/c mice are predisposed to developing spontaneous mammary tumors, which are further increased in a p53 heterozygous state. C57BL/6J mice are resistant to…”
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Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors
Published in Cancer research (Chicago, Ill.) (01-05-2007)“…The Rb/E2F pathway is deregulated in most human brain tumors, and the finding that loss of E2F1 reduced pituitary tumorigenesis in Rb(+/-) mice suggests that…”
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Docosahexaenoic acid reduces inflammation and joint destruction in mice with collagen-induced arthritis
Published in Inflammation research (01-12-2013)“…Objective This study was designed to determine the anti-inflammatory activity of docosahexaenoic acid (DHA), alone and in combination with eicosapentaenoic…”
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novel CRM1-dependent nuclear export signal in adenoviral E1A protein regulated by phosphorylation
Published in The FASEB journal (01-12-2006)“…Adenoviral E1A is a versatile protein that can reprogram host cells for efficient viral replication. The nuclear import of E1A is mediated by a nuclear…”
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320. Modeling Human Brain Cancer in Transgenic E2F1 Mice
Published in Molecular therapy (01-05-2006)“…Mutations disabling the retinoblastoma (Rb) pathway are among the most common in human cancers, including brain cancer. These mutations promote tumor…”
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Downmodulation of E1A protein expression as a novel strategy to design cancer-selective adenoviruses
Published in Neoplasia (New York, N.Y.) (01-08-2005)“…Oncolytic adenoviruses are being tested as potential therapies for human malignant tumors, including gliomas. Here we report for the first time that a mutation…”
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Downmodulation of El A Protein Expression as a Novel Strategy to Design Cancer-Selective Adenoviruses
Published in Neoplasia (New York, N.Y.) (01-08-2005)“…Oncolytic adenoviruses are being tested as potential therapies for human malignant tumors, including gliomas. Here we report for the first time that a mutation…”
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Docosahexaenoic acid algal oil reduces arthritis severity more effectively than fish oil in a mouse model of collagen‐induced arthritis
Published in The FASEB journal (01-04-2011)“…Omega‐3 fatty acids (n‐3), such as EPA and DHA, have been associated with the amelioration of chronic and acute inflammation. Although the efficacy of fish oil…”
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Downmodulation of E1A Protein Expression as a Novel Strategy to Design Cancer-Selective Adenoviruses1
Published in Neoplasia (New York, N.Y.) (01-08-2005)“…Oncolytic adenoviruses are being tested as potential therapies for human malignant tumors, including gliomas. Here we report for the first time that a mutation…”
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