Search Results - "Olson, Julie K."

Microglia Initiate Central Nervous System Innate and Adaptive Immune Responses through Multiple TLRs by Olson, Julie K, Miller, Stephen D

“…Microglia are the resident macrophage-like population in the CNS. Microglia remain quiescent until injury or infection activates the cells to perform effector…”
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Transcriptomic Profiling of Primary Microglia: Effects of miR-19a-3p and miR-19b-3p on Microglia Activation by Sahebdel, Faezeh, Zia, Aliabbas, Quinta, Hector Ramiro, Morse, Leslie R, Olson, Julie K, Battaglino, Ricardo A

“…Neuropathic pain resulting from spinal cord injury (SCI) is a significant secondary health issue affecting around 60% of individuals with SCI. After SCI,…”
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Immune response by microglia in the spinal cord by Olson, Julie K.

“…Microglia are the resident immune cells of the central nervous system (CNS) and share many immunological characteristics with peripheral macrophage. Microglia…”
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Exosomes Secreted by Microglia During Virus Infection in the Central Nervous System Activate an Inflammatory Response in Bystander Cells by Luong, Nhungoc, Olson, Julie K.

“…Microglia become persistently infected during Theiler’s murine encephalomyelitis virus (TMEV) infection in the central nervous system (CNS) of susceptible…”
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Endoplasmic reticulum stress regulates the innate immunity critical transcription factor IRF3 by Liu, Yi-Ping, Zeng, Ling, Tian, Austin, Bomkamp, Ashley, Rivera, Daniel, Gutman, Delia, Barber, Glen N, Olson, Julie K, Smith, Judith A

“…IFN regulatory factor 3 (IRF3) regulates early type I IFNs and other genes involved in innate immunity. We have previously shown that cells undergoing an…”
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Title: P2x7 Receptor Activation and Estrogen Status Drive Neuroinflammatory Mechanisms in a Rat Model for Dry Eye by Bereiter, David A, Rahman, Mostafeezur, Ahmed, Fabeeha, Thompson, Randall, Luong, Nhungoc, Olson, Julie K

“…Dry eye disease (DED) is recognized as a chronic inflammatory condition with an increase in tear osmolarity and loss of tear film integrity. DED is often…”
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Differential activation of astrocytes by innate and adaptive immune stimuli by Carpentier, Pamela A., Begolka, Wendy Smith, Olson, Julie K., Elhofy, Adam, Karpus, William J., Miller, Stephen D.

“…The immunologic privilege of the central nervous system (CNS) makes it crucial that CNS resident cells be capable of responding rapidly to infection…”
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Activation of microglia depends on Na+/H+ exchange-mediated H+ homeostasis by Liu, Yan, Kintner, Douglas B, Chanana, Vishal, Algharabli, Jehad, Chen, Xinzhi, Gao, Yanqin, Chen, Jun, Ferrazzano, Peter, Olson, Julie K, Sun, Dandan

“…H(+) extrusion is important for sustained NADPH oxidase activation after "respiratory" burst in macrophage/microglia activation. In this study, we investigated…”
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hsa-MiR-19a-3p and hsa-MiR-19b-3p Are Associated with Spinal Cord Injury-Induced Neuropathic Pain: Findings from a Genome-Wide MicroRNA Expression Profiling Screen by Ye, Liang, Morse, Leslie R, Falci, Scott P, Olson, Julie K, Shrivastava, Mayank, Nguyen, Nguyen, Linnman, Clas, Troy, Karen L, Battaglino, Ricardo A

“…Neuropathic pain in spinal cord injury (SCI) is associated with inflammation in both the peripheral and central nervous system (CNS), which may contribute to…”
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Immune responses of microglia in the spinal cord: Contribution to pain states by Schomberg, Dominic, Olson, Julie K.

“…The role of microglia and their contribution to the development and maintenance of pain states has emerged as an attractive field of study. Sensitization of…”
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Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mechanism by Boontanrart, Mandy, Hall, Samuel D, Spanier, Justin A, Hayes, Colleen E, Olson, Julie K

“…Abstract Microglia become activated immune cells during infection or disease in the central nervous system (CNS). However, the mechanisms that downregulate…”
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Pioglitazone, a PPARγ agonist, reduces cisplatin-evoked neuropathic pain by protecting against oxidative stress by Khasabova, Iryna A., Khasabov, Sergey G., Olson, Julie K., Uhelski, Megan L., Kim, Amy H., Albino-Ramírez, Alejandra M., Wagner, Chad L., Seybold, Virginia S., Simone, Donald A.

“…Painful peripheral neuropathy is a dose-limiting side effect of cisplatin treatment. Using a murine model of cisplatin-induced hyperalgesia, we determined…”
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Initiation and Exacerbation of Autoimmune Demyelination of the Central Nervous System via Virus-Induced Molecular Mimicry: Implications for the Pathogenesis of Multiple Sclerosis by CROXFORD, J. Ludovic, OLSON, Julie K, ANGER, Holly A, MILLER, Stephen D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effect of the innate immune response on development of Theiler’s murine encephalomyelitis virus-induced demyelinating disease by Olson, Julie K.

“…Theiler’s murine encephalomyelitis virus (TMEV) infection of susceptible mice leads to the development of demyelinating disease in the central nervous system…”
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The bivalent ligand MCC22 potently attenuates hyperalgesia in a mouse model of cisplatin-evoked neuropathic pain without tolerance or reward by Cataldo, Giuseppe, Erb, Samuel J., Lunzer, Mary M., Luong, Nhungoc, Akgün, Eyup, Portoghese, Philip S., Olson, Julie K., Simone, Donald A.

“…Cisplatin and other widely employed platinum-based anticancer agents produce chemotherapy-induced peripheral neuropathy (CIPN) that often results in pain and…”
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Innate Immune CD11b+Gr-1+ Cells, Suppressor Cells, Affect the Immune Response during Theiler's Virus-Induced Demyelinating Disease by Bowen, Jenna L, Olson, Julie K

“…Multiple sclerosis is a demyelinating disease associated with an inflammatory immune response in the CNS. Theiler's murine encephalomyelitis virus…”
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Bivalent ligand MCC22 potently attenuates nociception in a murine model of sickle cell disease by Cataldo, Giuseppe, Lunzer, Mary M., Olson, Julie K., Akgün, Eyup, Belcher, John D., Vercellotti, Gregory M., Portoghese, Philip S., Simone, Donald A.

“…Sickle cell disease (SCD) is a chronic inflammatory disorder accompanied by chronic pain. In addition to ongoing pain and hyperalgesia, vaso-occlusive…”
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Extracellular Vesicles Secreted by Tumor Cells Promote the Generation of Suppressive Monocytes by Luong, Nhungoc, Lenz, Jennifer A, Modiano, Jaime F, Olson, Julie K

“…Monocytes are among the first cells to infiltrate the tumor microenvironment. The conversion of monocytes to suppressor cells in the tumor microenvironment is…”
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The Innate Immune Response Affects the Development of the Autoimmune Response in Theiler's Virus-Induced Demyelinating Disease by Olson, Julie K, Miller, Stephen D

“…Multiple sclerosis (MS) is a human CNS autoimmune demyelinating disease. Epidemiological evidence has suggested a role for virus infection in the initiation…”
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IFNγ influences type I interferon response and susceptibility to Theiler's virus-induced demyelinating disease by Bowen, Jenna L, Olson, Julie K

“…Theiler's murine encephalomyelitis virus (TMEV) induces a demyelinating disease in susceptible SJL mice that has similarities to multiple sclerosis in humans…”
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