Search Results - "Olson, Jeremy P."

Optically Selective Two-Photon Uncaging of Glutamate at 900 nm by Olson, Jeremy P, Kwon, Hyung-Bae, Takasaki, Kevin T, Chiu, Chiayu Q, Higley, Michael J, Sabatini, Bernardo L, Ellis-Davies, Graham C. R

“…We have synthesized a 7-diethylaminocoumarin (DEAC) derivative that allows wavelength-selective two-photon uncaging at 900 nm versus 720 nm. This new caging…”
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Cloaked Caged Compounds: Chemical Probes for Two‐Photon Optoneurobiology by Richers, Matthew T., Amatrudo, Joseph M., Olson, Jeremy P., Ellis‐Davies, Graham C. R.

“…Caged neurotransmitters, in combination with focused light beams, enable precise interrogation of neuronal function, even at the level of single synapses…”
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Asymmetric [4 + 3] Cycloadditions between Benzofuranyldiazoacetates and Dienes:  Formal Synthesis of (+)-Frondosin B by Olson, Jeremy P, Davies, Huw M. L

“…The reaction of benzofuranyldiazoacetates with 1,3-dienes catalyzed by the dirhodium tetracarboxylate Rh2(R-DOSP)4, generates formal [4 + 3] cycloadducts with…”
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Wavelength-Selective One- and Two-Photon Uncaging of GABA by Amatrudo, Joseph M, Olson, Jeremy P, Lur, G, Chiu, Chiayu Q, Higley, Michael J, Ellis-Davies, Graham C. R

“…We have synthesized photolabile 7-diethylamino coumarin (DEAC) derivatives of γ-aminobutyric acid (GABA). These caged neurotransmitters efficiently release…”
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Spectral Evolution of a Photochemical Protecting Group for Orthogonal Two-Color Uncaging with Visible Light by Olson, Jeremy P, Banghart, Matthew R, Sabatini, Bernardo L, Ellis-Davies, Graham C. R

“…Caged compounds are molecules rendered functionally inert by derivatization with a photochemical protecting group. We describe the design logic behind the…”
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Caged compounds for multichromic optical interrogation of neural systems by Amatrudo, Joseph M., Olson, Jeremy P., Agarwal, Hitesh K., Ellis-Davies, Graham C. R.

“…Caged compounds are widely used by neurophysiologists to study many aspects of cellular signaling in glia and neurons. Biologically inert before irradiation,…”
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Guide to enantioselective dirhodium(II)-catalyzed cyclopropanation with aryldiazoacetates by Chepiga, Kathryn M., Qin, Changming, Alford, Joshua S., Chennamadhavuni, Spandan, Gregg, Timothy M., Olson, Jeremy P., Davies, Huw M.L.

“…Catalytic enantioselective methods for the generation of cyclopropanes have been of long standing pharmaceutical interest. Chiral dirhodium(II) catalysts prove…”
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Asymmetric [4 + 3] Cycloadditions between Benzofuranyldiazoacetates and Dienes: Formal Synthesis of (+)-Frondosin B by Olson, Jeremy P, Davies, Huw M. L

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Synthesis and evaluation of 1,2,4-methyltriazines as mGluR5 antagonists by Olson, Jeremy P, Gichinga, Moses G, Butala, Elizabeth, Navarro, Hernan A, Gilmour, Brian P, Carroll, F Ivy

“…In previous studies we showed that 3-(substituted phenylethynyl)-5-methyl[1,2,4]triazine analogues of MPEP were potent antagonists of glutamate-mediated…”
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Cloaked Caged Compounds: Chemical Probes for Two‐Photon Optoneurobiology by Richers, Matthew T., Amatrudo, Joseph M., Olson, Jeremy P., Ellis‐Davies, Graham C. R.

“…Abstract Caged neurotransmitters, in combination with focused light beams, enable precise interrogation of neuronal function, even at the level of single…”
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Preparation of a series of 5-methyl-3-(substituted)-[1,2,4]triazines by Gichinga, Moses G., Olson, Jeremy P., Butala, Elizabeth, Gilmour, Brian P., Navarro, Hernán H., Ivy Carroll, F.

“…Procedures for the synthesis of thirty-six 5-methyl-3-(substituted)-[1,2,4]triazines have been described. These compounds were evaluated for antagonism at…”
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Synthesis and Evaluation of Metabotropic Glutamate Receptor Subtype 5 Antagonists Based on Fenobam by Gichinga, Moses G, Olson, Jeremy P, Butala, Elizabeth, Navarro, Hernán A, Gilmour, Brian P, Mascarella, S. Wayne, Carroll, F. Ivy

“…In an effort to discover potent and selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonists, 15 tetrahydropyrimidinone analogues of…”
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