Search Results - "Olson, Jane M."

Overview of QTL mapping software and introduction to Map Manager QT by Manly, K F, Olson, J M

“…At least ten software packages are available for marker-based detection and localization of loci contributing to quantitative traits in experimental animals…”
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Genome scan for familial abdominal aortic aneurysm using sex and family history as covariates suggests genetic heterogeneity and identifies linkage to chromosome 19q13 by SHIBAMURA, Hidenori, OLSON, Jane M, LIMET, Raymond, MACKEAN, Gerald L, DEFAWE, Olivier, VERLOES, Alain, ARTHUR, Claudette, LOSSING, Alan G, BURNETT, Marjorie, SUEDA, Taijiro, KUIVANIEMI, Helena, VAN VLIJMEN-VAN KEULEN, Clarissa, BUXBAUM, Sarah G, DUDEK, Doreen M, TROMP, Gerard, OGATA, Toru, SKUNCA, Magdalena, SAKALIHASAN, Natzi, PALS, Gerard

“…Abdominal aortic aneurysm (AAA) is a relatively common disease, with 1% to 2% of the population harboring aneurysms. Genetic risk factors are likely to…”
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The Fibromyalgia Family Study: A Genome‐Wide Linkage Scan Study by Arnold, Lesley M., Fan, Jinbo, Russell, I. Jon, Yunus, Muhammad B., Khan, Muhammad Asim, Kushner, Irving, Olson, Jane M., Iyengar, Sudha K.

“…Objective Familial aggregation of fibromyalgia has been increasingly recognized. The goal of this study was to conduct a genome‐wide linkage scan to identify…”
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Search for intracranial aneurysm susceptibility gene(s) using Finnish families by Olson, Jane M, Vongpunsawad, Sompong, Kuivaniemi, Helena, Ronkainen, Antti, Hernesniemi, Juha, Ryynänen, Markku, Kim, Lee-Lian, Tromp, Gerard

“…Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured…”
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Linkage analysis of candidate loci for end-stage renal disease due to diabetic nephropathy by IYENGAR, Sudha K, FOX, Katherine A, SEDOR, John R, SCHACHERE, Marlene, MANZOOR, Fauzia, SLAUGHTER, Mary E, COVIC, Adrian M, ORLOFF, S. Mohammed, HAYDEN, Patrick S, OLSON, Jane M, SCHELLING, Jeffrey R

“…Diabetic nephropathy (DN), a major cause of ESRD, is undoubtedly multifactorial and is caused by environmental and genetic factors. To identify a genetic basis…”
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Segregation at three loci explains familial and population risk in Hirschsprung disease by Angrist, Misha, Buys, Charles, Fornage, Myriam, Gabriel, Stacey Bolk, Attié-Bitach, Tania, Pelet, Anna, Hofstra, Robert, Olson, Jane M, Lyonnet, Stanislas, Munnich, Arnold, Chakravarti, Aravinda, Steffann, Julie, Salomon, Rémi, Amiel, Jeanne

“…Hirschsprung disease (HSCR), the most common hereditary cause of intestinal obstruction, shows considerable variation and complex inheritance. Coding sequence…”
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The design, execution, and interpretation of genetic association studies to decipher complex diseases by Romero, Roberto, Kuivaniemi, Helena, Tromp, Gerard, Olson, Jane M.

“…Genetic association studies are becoming increasingly frequent in the obstetric and gynecologic literature and they are considered central to the deciphering…”
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Candidate-gene association study of mothers with pre-eclampsia, and their infants, analyzing 775 SNPs in 190 genes by Goddard, Katrina A B, Tromp, Gerard, Romero, Roberto, Olson, Jane M, Lu, Qing, Xu, Zhiying, Parimi, Neeta, Nien, Jyh Kae, Gomez, Ricardo, Behnke, Ernesto, Solari, Margarita, Espinoza, Jimmy, Santolaya, Joaquin, Chaiworapongsa, Tinnakorn, Lenk, Guy M, Volkenant, Kimberly, Anant, Madan Kumar, Salisbury, Benjamin A, Carr, Janet, Lee, Min Soeb, Vovis, Gerald F, Kuivaniemi, Helena

“…Pre-eclampsia (PE) affects 5-7% of pregnancies in the US, and is a leading cause of maternal death and perinatal morbidity and mortality worldwide. To identify…”
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Intracranial Aneurysms in Finnish Families: Confirmation of Linkage and Refinement of the Interval to Chromosome 19q13.3 by van der Voet, Monique, Olson, Jane M., Kuivaniemi, Helena, Dudek, Doreen M., Skunca, Magdalena, Ronkainen, Antti, Niemelä, Mika, Jääskeläinen, Juha, Hernesniemi, Juha, Helin, Katariina, Leinonen, Eira, Biswas, Moumita, Tromp, Gerard

“…We recently reported a two-stage genomewide screen of 48 sib pairs affected with intracranial aneurysms (IAs) that revealed suggestive linkage to chromosome…”
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Model-Free Linkage Analysis with Covariates Confirms Linkage of Prostate Cancer to Chromosomes 1 and 4 by Goddard, Katrina A.B., Witte, John S., Suarez, Brian K., Catalona, William J., Olson, Jane M.

“…As with many complex genetic diseases, genome scans for prostate cancer have given conflicting results, often failing to provide replication of previous…”
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Mapping of a susceptibility locus for Crohn's disease on chromosome 16 by Hugot, Jean-Pierre, Laurent-Puig, Pierre, Gower-Rousseau, Corine, Olson, Jane M, Lee, John C, Beaugerie, Laurent, Naom, Isam, Dupas, Jean-Louis, Van Gossum, André, Orholm, Marianne, Bonaiti-Pellie, Catherine, Weissenbach, Jean, Mathew, Christopher G, Lennard-Jones, John E, Cortot, Antoine, Colombel, Jean-Frédéric, Thomas, Gilles

“…Crohn's disease (CD) and ulcerative colitis are the major forms of chronic inflammatory bowel diseases in the western world, and occur in young adults with an…”
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A Second Locus for Very-Late-Onset Alzheimer Disease: A Genome Scan Reveals Linkage to 20p and Epistasis between 20p and the Amyloid Precursor Protein Region by Olson, Jane M., Goddard, Katrina A.B., Dudek, Doreen M.

“…We used a covariate-based linkage method to reanalyze genome scan data from affected sibships collected by the Alzheimer Disease (AD) Genetics Initiative of…”
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The Family Investigation of Nephropathy and Diabetes (FIND): Design and methods by Knowler, William C., Coresh, Josef, Elston, Robert C., Freedman, Barry I., Iyengar, Sudha K., Kimmel, Paul L., Olson, Jane M., Plaetke, Rosemarie, Sedor, John R., Seldin, Michael F.

“…The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic nephropathy. It is…”
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MMP13 promoter polymorphism is associated with atherosclerosis in the abdominal aorta of young black males by Yoon, Sungpil, Kuivaniemi, Helena, Gatalica, Zoran, Olson, Jane M., Butticè, Giovanna, Ye, Siqin, Norris, Brent A., Malcom, Gray T., Strong, Jack P., Tromp, Gerard

“…Previous studies suggested that remodeling of connective tissue is important in progression of atherosclerosis. We investigated the importance of matrix…”
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The Amyloid Precursor Protein Locus and Very-Late-Onset Alzheimer Disease by Olson, Jane M., Goddard, Katrina A.B., Dudek, Doreen M.

“…Although mutations in the amyloid-β precursor protein (APP) gene are known to confer high risk of Alzheimer disease (AD) to a small percentage of families in…”
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An autosomal screen for genes that predispose to celiac disease in the western counties of Ireland by McCombs, Candace C, Stevens, Fiona M, McCarthy, Ciaran F, Olson, Jane M, Zhong, Fei, Michalski, Joseph P, Elston, Robert C

“…Celiac disease is a strongly heritable gastrointestinal illness that is an especially important model of the genetically complex multifactorial immune mediated…”
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Genetic linkage of systemic lupus erythematosus to 13q32 in African american families with affected male members by CHAO XING, GRAY-MCGUIRE, Courtney, KELLY, Jennifer A, GARRIOTT, Phillip, BUKULMEZ, Hulya, HARLEY, John B, OLSON, Jane M

“…Systemic lupus erythematosus (SLE) is a complex autoimmune disorder involving genetic and environmental factors. Previously, our group showed that SLE females…”
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Ascertainment Adjustment: Where Does It Take Us? by Burton, Paul R., Palmer, Lyle J., Jacobs, Kevin, Keen, Kevin J., Olson, Jane M., Elston, Robert C.

“…It is commonly assumed that the parameter estimates of a statistical genetics model that has been adjusted for ascertainment will estimate parameters in the…”
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Evidence of linkage and association on chromosome 20 for late-onset Alzheimer disease by GODDARD, Katrina A. B, OLSON, Jane M, PAYAMI, Haydeh, VAN DER VOET, Monique, KUIVANIEMI, Helena, TROMP, Gerard

“…Recently, we reported evidence of linkage on chromosome 20 for Alzheimer disease (AD) using a novel statistical approach to incorporate covariates (e.g., age,…”
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Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study by Bukulmez, Hulya, Fife, Mark, Tsoras, Monica, Thompson, Susan D, Twine, Natalie A, Woo, Patricia, Olson, Jane M, Elston, Robert C, Glass, David N, Colbert, Robert A

“…Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term…”
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