Search Results - "Olson, Gary"

Supporting Scientific Collaboration: Methods, Tools and Concepts by Jirotka, Marina, Lee, Charlotte P., Olson, Gary M.

“…This paper discusses the interrelationship between e-Science and CSCW in terms of key substantive, methodological and conceptual innovations made in both…”
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Promote Students' Function Reasoning with Techtivities by Olson, Gary A., Johnson, Heather Lynn

“…Students enrolled in introductory math courses, such as college algebra, deserve to do more than find answers and fix mistakes. We present one interactive…”
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Megalin Mediates Selenoprotein P Uptake by Kidney Proximal Tubule Epithelial Cells by Olson, Gary E., Winfrey, Virginia P., Hill, Kristina E., Burk, Raymond F.

“…Selenoprotein P (Sepp1) contains most of the selenium in blood plasma, and it is utilized by the kidney, brain, and testis as a selenium source for…”
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Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212 by Wagner, Jessica, Kline, Christina Leah, Ralff, Marie D, Lev, Avital, Lulla, Amriti, Zhou, Lanlan, Olson, Gary L, Nallaganchu, Bhaskara Rao, Benes, Cyril H, Allen, Joshua E, Prabhu, Varun V, Stogniew, Martin, Oster, Wolfgang, El-Deiry, Wafik S

“…Anti-cancer small molecule ONC201 upregulates the integrated stress response (ISR) and acts as a dual inactivator of Akt/ERK, leading to TRAIL gene activation…”
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Discovery and clinical introduction of first-in-class imipridone ONC201 by Allen, Joshua E, Kline, C Leah B, Prabhu, Varun V, Wagner, Jessica, Ishizawa, Jo, Madhukar, Neel, Lev, Avital, Baumeister, Marie, Zhou, Lanlan, Lulla, Amriti, Stogniew, Martin, Schalop, Lee, Benes, Cyril, Kaufman, Howard L, Pottorf, Richard S, Nallaganchu, B Rao, Olson, Gary L, Al-Mulla, Fahd, Duvic, Madeleine, Wu, Gen Sheng, Dicker, David T, Talekar, Mala K, Lim, Bora, Elemento, Olivier, Oster, Wolfgang, Bertino, Joseph, Flaherty, Keith, Wang, Michael L, Borthakur, Gautam, Andreeff, Michael, Stein, Mark, El-Deiry, Wafik S

“…ONC201 is the founding member of a novel class of anti-cancer compounds called imipridones that is currently in Phase II clinical trials in multiple advanced…”
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Maternal‐fetal transfer of selenium in the mouse by Burk, Raymond F., Olson, Gary E., Hill, Kristina E., Winfrey, Virginia P., Motley, Amy K., Kurokawa, Suguru

“…Selenoprotein P (Sepp1) is taken up by receptor‐mediated endocytosis for its selenium. The other extracellular selenoprotein, glutathione peroxidase‐3 (Gpx3),…”
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Apolipoprotein E Receptor-2 (ApoER2) Mediates Selenium Uptake from Selenoprotein P by the Mouse Testis by Olson, Gary E., Winfrey, Virginia P., NagDas, Subir K., Hill, Kristina E., Burk, Raymond F.

“…Selenium is a micronutrient that is essential for the production of normal spermatozoa. The selenium-rich plasma protein selenoprotein P (Sepp1) is required…”
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Extracellular glutathione peroxidase (Gpx3) binds specifically to basement membranes of mouse renal cortex tubule cells by Olson, Gary E, Whitin, John C, Hill, Kristina E, Winfrey, Virginia P, Motley, Amy K, Austin, Lori M, Deal, Jacqualyn, Cohen, Harvey J, Burk, Raymond F

“…Glutathione peroxidase-3 (Gpx3), also known as plasma or extracellular glutathione peroxidase, is a selenoprotein secreted primarily by kidney proximal…”
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Anchoring Inverse and Injective Functions with Techtivities by Olson, Gary A., Johnson, Heather Lynn, Robinson, Rebecca, Knurek, Robert, Whitmore, Kristin A.

“…Inverse and injective functions are topics in most college algebra courses. Yet, current materials and course structures may not afford students' conceptual…”
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Two fibrinogen-like proteins, FGL1 and FGL2 are disulfide-linked subunits of oligomers that specifically bind nonviable spermatozoa by Nagdas, Subir K., Winfrey, Virginia P., Olson, Gary E.

“…Nevertheless, a nonviable sperm population is present in the cauda epididymidis of many species. Degenerating spermatozoa release enzymes that could have…”
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Glutathione peroxidase-3 produced by the kidney binds to a population of basement membranes in the gastrointestinal tract and in other tissues by Burk, Raymond F, Olson, Gary E, Winfrey, Virginia P, Hill, Kristina E, Yin, Dengping

“…Glutathione peroxidase-3 (Gpx3), the extracellular glutathione peroxidase synthesized largely in the kidney, binds to basement membranes of renal cortical…”
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Distance Matters by Olson, Gary M., Olson, Judith S.

“…Giant strides in information technology at the turn of the century may have unleashed unreachable goals. With the invention of groupware, people expect to…”
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A Case Study of a Multi-Institution Replication of a Comprehensive GTA Teacher Training Program by Manzanares, RaKissa, Webb, Jessica, Harrell-Williams, Leigh M., Olson, Gary A., Houston, Scotty, Lanius, Melinda, Funkhouser, Kelsey, Shannon, David, Gomez, Josias O., Jacobson, Michael, Merchant, Lora

“…A comprehensive graduate teaching assistant (GTA) training program in mathematical sciences designed at one institution is being adapted and replicated at two…”
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The angular structure of ONC201, a TRAIL pathway-inducing compound, determines its potent anti-cancer activity by Wagner, Jessica, Kline, Christina Leah, Pottorf, Richard S, Nallaganchu, Bhaskara Rao, Olson, Gary L, Dicker, David T, Allen, Joshua E, El-Deiry, Wafik S

“…We previously identified TRAIL-inducing compound 10 (TIC10), also known as NSC350625 or ONC201, from a NCI chemical library screen as a small molecule that has…”
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Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis by Ji, Niannian, Somanaboeina, Animesh, Dixit, Aakanksha, Kawamura, Kazuyuki, Hayward, Neil J, Self, Christopher, Olson, Gary L, Forsthuber, Thomas G

“…The strong association of HLA-DR2b (DRB1*1501) with multiple sclerosis (MS) suggests this molecule as prime target for specific immunotherapy. Inhibition of…”
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HLA-DR15-specific inhibition attenuates autoreactivity to the Goodpasture antigen by Huynh, Megan, Eggenhuizen, Peter J., Olson, Gary L., Rao, N. Bhaskara, Self, Christopher R., Sun, Yanjun, Holdsworth, Stephen R., Kitching, A. Richard, Ooi, Joshua D.

“…Goodpasture's disease manifests as rapidly progressive glomerulonephritis. Current immunosuppressive treatments do not specifically target the pathological…”
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The Selenium-rich C-terminal Domain of Mouse Selenoprotein P Is Necessary for the Supply of Selenium to Brain and Testis but Not for the Maintenance of Whole Body Selenium by Hill, Kristina E., Zhou, Jiadong, Austin, Lori M., Motley, Amy K., Ham, Amy-Joan L., Olson, Gary E., Atkins, John F., Gesteland, Raymond F., Burk, Raymond F.

“…Selenoprotein P (Sepp1) has two domains with respect to selenium content: the N-terminal, selenium-poor domain and the C-terminal, selenium-rich domain. To…”
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Selenoprotein P Is Required for Mouse Sperm Development by OLSON, Gary E, WINFREY, Virginia P, NAGDAS, Subir K, HILL, Kristina E, BURK, Raymond F

“…Selenoprotein P (SEPP1), an extracellular glycoprotein of unknown function, is a unique member of the selenoprotein family that, depending on species, contains…”
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Deletion of Apolipoprotein E Receptor-2 in Mice Lowers Brain Selenium and Causes Severe Neurological Dysfunction and Death When a Low-Selenium Diet Is Fed by Burk, Raymond F, Hill, Kristina E, Olson, Gary E, Weeber, Edwin J, Motley, Amy K, Winfrey, Virginia P, Austin, Lori M

“…Selenoprotein P (Sepp1) is a plasma and extracellular protein that is rich in selenium. Deletion of Sepp1 results in sharp decreases of selenium levels in the…”
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Correction: Discovery and clinical introduction of first-in-class imipridone ONC201 by Allen, Joshua E., Kline, C. Leah B., Prabhu, Varun V., Wagner, Jessica, Ishizawa, Jo, Madhukar, Neel, Lev, Avital, Baumeister, Marie, Zhou, Lanlan, Lulla, Amriti, Stogniew, Martin, Schalop, Lee, Benes, Cyril, Kaufman, Howard L., Pottorf, Richard S., Nallaganchu, B. Rao, Olson, Gary L., Al-Mulla, Fahd, Duvic, Madeleine, Wu, Gen Sheng, Dicker, David T., Talekar, Mala K., Lim, Bora, Elemento, Olivier, Oster, Wolfgang, Bertino, Joseph, Flaherty, Keith, Wang, Michael L., Borthakur, Gautam, Andreeff, Michael, Stein, Mark, El-Deiry, Wafik S.

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