Search Results - "Olson, Erika M"
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Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function
Published in Diabetes (New York, N.Y.) (01-07-2018)“…Loss of functional β-cell mass is an early feature of type 1 diabetes. To release insulin, β-cells require soluble -ethylmaleimide-sensitive factor attachment…”
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Expression Levels of p21‐activated kinase (PAK1) in the Skeletal Muscle Exert Feedback to Influence Pancreatic β‐cell Functionality in vivo
Published in The FASEB journal (01-04-2020)“…Abstract only Skeletal muscle accounts for ~80% of insulin‐stimulated glucose uptake. The Group I p21–activated kinase 1 (PAK1) is required for the…”
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Journal Article -
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Regulation of Insulin Sensitivity by Skeletal Muscle Specific Modulation Of p21‐Activated Kinase 1 (PAK1)
Published in The FASEB journal (01-04-2018)“…Impaired skeletal muscle (skm) insulin signaling results in insulin resistance and the development of type 2 diabetes (T2D). Insulin binding to its receptors…”
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Syntaxin 4 (STX4) Enrichment in Skeletal Muscle Remediates Insulin Resistance via and Improving Mitochondrial Function
Published in The FASEB journal (01-04-2019)“…Type 2 diabetes afflicts 10% of the US population and is the result of both peripheral insulin resistance (skeletal muscle and adipose tissue) as well as…”
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Journal Article