Search Results - "Olson, Diane R"

Regulation of Epithelial Sodium Channel Trafficking by Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) by Sharotri, Vikas, Collier, Daniel M., Olson, Diane R., Zhou, Ruifeng, Snyder, Peter M.

“…The epithelial Na+ channel (ENaC) is critical for Na+ homeostasis and blood pressure control. Defects in its regulation cause inherited forms of hypertension…”
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Serum and Glucocorticoid-regulated Kinase Modulates Nedd4-2-mediated Inhibition of the Epithelial Na+Channel by Snyder, Peter M., Olson, Diane R., Thomas, Brittany C.

“…The epithelial Na+ channel (ENaC) forms the pathway for Na+ absorption across epithelia, including the kidney collecting duct, where it plays a critical role…”
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cAMP and Serum and Glucocorticoid-inducible Kinase (SGK) Regulate the Epithelial Na+ Channel through Convergent Phosphorylation of Nedd4-2 by Snyder, Peter M, Olson, Diane R, Kabra, Rajesh, Zhou, Ruifeng, Steines, Jennifer C

“…The epithelial Na + channel (ENaC) functions as a pathway for epithelial Na + transport, contributing to Na + homeostasis and blood pressure control…”
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Liddle's Syndrome Mutations Increase Na⁺ Transport through Dual Effects on Epithelial Na⁺ Channel Surface Expression and Proteolytic Cleavage by Knight, Kristin K., Olson, Diane R., Zhou, Ruifeng, Snyder, Peter M.

“…Liddle's syndrome, an inherited form of hypertension, is caused by mutations that delete or disrupt a C-terminal PY motif in the epithelial Na⁺ channel (ENaC)…”
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Relative Contribution of Nedd4 and Nedd4-2 to ENaC Regulation in Epithelia Determined by RNA Interference by Snyder, Peter M., Steines, Jennifer C., Olson, Diane R.

“…Epithelial Na+ transport is regulated in large part by mechanisms that control expression of the epithelial Na+ channel (ENaC) at the cell surface. Nedd4 and…”
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Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel by McDonald, Fiona J, Western, Andrea H, McNeil, John D, Thomas, Brittany C, Olson, Diane R, Snyder, Peter M

“…The epithelial Na(+) channel (ENaC) is a critical component of the pathway maintaining salt and water balance. The channel is regulated by members of the Nedd4…”
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Hrs Controls Sorting of the Epithelial Na+ Channel between Endosomal Degradation and Recycling Pathways by Zhou, Ruifeng, Kabra, Rajesh, Olson, Diane R., Piper, Robert C., Snyder, Peter M.

“…Epithelial Na+ absorption is regulated by Nedd4-2, an E3 ubiquitin ligase that reduces expression of the epithelial Na+ channel (ENaC) at the cell surface…”
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Regulation of the delta and alpha epithelial sodium channel (ENaC) by ubiquitination and Nedd8 by Ly, Kevin, McIntosh, C. Joy, Biasio, Wolfgang, Liu, Yongfeng, Ke, Ying, Olson, Diane R., Miller, John H., Page, Rachel, Snyder, Peter M., McDonald, Fiona J.

“…The δ epithelial sodium channel (δENaC) is a proton‐activated, sodium‐selective, amiloride‐sensitive ion channel in the ENaC/degenerin family of ion channels…”
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A Pore Segment in DEG/ENaC Na+ Channels by Snyder, Peter M., Olson, Diane R., Bucher, Daniel B.

“…DEG/ENaC Na+ channels have diverse functions, including Na+ absorption, neurotransmission, and sensory transduction. The ability of these channels to…”
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Multiple WW Domains, but Not the C2 Domain, Are Required for Inhibition of the Epithelial Na+ Channel by Human Nedd4 by Snyder, P M, Olson, D R, McDonald, F J, Bucher, D B

“…The epithelial Na + channel (ENaC) absorbs Na + across the apical membrane of epithelia. The activity of ENaC is controlled by its interaction with Nedd4;…”
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Gating induces a conformational change in the outer vestibule of ENaC by Snyder, P M, Bucher, D B, Olson, D R

“…The epithelial Na(+) channel (ENaC) is comprised of three homologous subunits (alpha, beta, and gamma). The channel forms the pathway for Na(+) absorption in…”
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Liddle’s syndrome mutations increase proteolytic cleavage of ENaC by Knight, Kristin K, Olson, Diane R, Zhou, Ruifeng, Snyder, Peter M

“…□Liddle’s syndrome mutations increase epithelial Na transport by increasing ENaC surface expression. Previous work suggested that Liddle’s mutations might also…”
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Liddle's syndrome mutations increase Na super(+) transport through dual effects on epithelial Na super(+) channel surface expression and proteolytic cleavage by Knight, Kristin K, Olson, Diane R, Zhou, Ruifeng, Snyder, Peter M

“…Liddle's syndrome, an inherited form of hypertension, is caused by mutations that delete or disrupt a C-terminal PY motif in the epithelial Na super(+) channel…”
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Diabetes remission and glycemic response to pre-bariatric surgery diet by Biro, Steven M., MS, Olson, Diane L., RD, Garren, Michael J., MD, Gould, Jon C., MD

“…Abstract Background Before bariatric surgery, some patients with type 2 diabetes mellitus (T2DM) experience improvement in blood glucose control and reduced…”
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