Search Results - "Olsen Saraiva Camara, Niels"
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The Macrophage Switch in Obesity Development
Published in Frontiers in immunology (05-01-2016)“…Immune cell infiltration in (white) adipose tissue (AT) during obesity is associated with the development of insulin resistance. In AT, the main population of…”
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Carbon monoxide protects the kidney through the central circadian clock and CD39
Published in Proceedings of the National Academy of Sciences - PNAS (06-03-2018)“…Ischemia reperfusion injury (IRI) is the predominant tissue insult associated with organ transplantation. Treatment with carbon monoxide (CO) modulates the…”
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3
Butyrate Attenuates Lung Inflammation by Negatively Modulating Th9 Cells
Published in Frontiers in immunology (2019)“…Th9 cells orchestrate allergic lung inflammation by promoting recruitment and activation of eosinophils and mast cells, and by stimulating epithelial mucus…”
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Mesenchymal Stem Cells Attenuate Renal Fibrosis Through Immune Modulation and Remodeling Properties in a Rat Remnant Kidney Model
Published in Stem cells (Dayton, Ohio) (01-12-2009)“…Mesenchymal stem cells (MSCs) have regenerative properties in acute kidney injury, but their role in chronic kidney diseases is still unknown. More…”
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Lower peripheral blood Toll-like receptor 3 expression is associated with an unfavorable outcome in severe COVID-19 patients
Published in Scientific reports (27-07-2021)“…The role of innate immunity in COVID-19 is not completely understood. Therefore, this study explored the impact of Severe Acute Respiratory Syndrome…”
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Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid
Published in Clinical science (1979) (15-01-2021)“…Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by insulin-producing pancreatic β-cell destruction and hyperglycemia. While…”
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Understanding the Metabolic Profile of Macrophages During the Regenerative Process in Zebrafish
Published in Frontiers in physiology (24-05-2019)“…In contrast to mammals, lower vertebrates, including zebrafish ( ), have the ability to regenerate damaged or lost tissues, such as the caudal fin, which makes…”
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TLR2, TLR4 and the MYD88 signaling pathway are crucial for neutrophil migration in acute kidney injury induced by sepsis
Published in PloS one (24-05-2012)“…The aim of this study was to investigate the role of TLR2, TLR4 and MyD88 in sepsis-induced AKI. C57BL/6 TLR2(-/-), TLR4(-/-) and MyD88(-/-) male mice were…”
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Low Level Laser Therapy Reduces the Development of Lung Inflammation Induced by Formaldehyde Exposure
Published in PloS one (16-11-2015)“…Lung diseases constitute an important public health problem and its growing level of concern has led to efforts for the development of new therapies,…”
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They Must Hold Tight: Junction Proteins, Microbiota And Immunity In Intestinal Mucosa
Published in Current protein & peptide science (01-01-2015)“…Homeostasis of the immune system depends on several factors. The gastrointestinal tract plays an important role in maintaining our immune system. With this…”
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Acute effects of power and resistance exercises on hemodynamic measurements of older women
Published in Clinical interventions in aging (01-01-2017)“…The purpose of this study was to compare the acute effects of resistance training (RT) and power training (PT) on the hemodynamic parameters and nitric oxide…”
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Beneficial effects of vitamin C treatment on pregnant rats exposed to formaldehyde: Reversal of immunosuppression in the offspring
Published in Toxicology and applied pharmacology (01-06-2016)“…Inhalation of formaldehyde (FA) during the pregnancy induces oxidative stress in the uterus, and here we hypothesized that this mechanism may be responsible…”
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Exercise during pregnancy protects adult mouse offspring from diet-induced obesity
Published in Nutrition & metabolism (18-12-2015)“…Physical exercise induces positive alterations in gene expression involved in the metabolism of obesity. Maternal exercise provokes adaptations soon after…”
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Inflammation in Renal Diseases: New and Old Players
Published in Frontiers in pharmacology (08-10-2019)“…Inflammation, a process intimately linked to renal disease, can be defined as a complex network of interactions between renal parenchymal cells and resident…”
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The role of uric acid in inflammasome-mediated kidney injury
Published in Current opinion in nephrology and hypertension (01-07-2020)“…PURPOSE OF REVIEWUric acid is produced after purine nucleotide degradation, upon xanthine oxidase catalytic action. In the evolutionary process, humans lost…”
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Early modulation of inflammation by mesenchymal stem cell after acute kidney injury
Published in International immunopharmacology (01-06-2009)“…Therapy with stem cells has showed to be promising for acute kidney injury (AKI), although how it works is still controversial. Modulation of the inflammatory…”
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Mitochondria as central hub of the immune system
Published in Redox biology (01-09-2019)“…Nearly 130 years after the first insights into the existence of mitochondria, new rolesassociated with these organelles continue to emerge. As essential hubs…”
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Soluble Uric Acid Activates the NLRP3 Inflammasome
Published in Scientific reports (13-01-2017)“…Uric acid is a damage-associated molecular pattern (DAMP), released from ischemic tissues and dying cells which, when crystalized, is able to activate the…”
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Extracellular Vesicles isolated from Mesenchymal Stromal Cells Modulate CD4 + T Lymphocytes Toward a Regulatory Profile
Published in Cells (Basel, Switzerland) (23-04-2020)“…Mesenchymal stromal cells (MSCs) can generate immunological tolerance due to their regulatory activity in many immune cells. Extracellular vesicles (EVs)…”
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Melanopsin (Opn4) is an oncogene in cutaneous melanoma
Published in Communications biology (13-05-2022)“…The search for new therapeutical targets for cutaneous melanoma and other cancers is an ongoing task. We expanded this knowledge by evaluating whether opsins,…”
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