Search Results - "Olsen, Scott R."

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer by Man, Si Ming, Zhu, Qifan, Zhu, Liqin, Liu, Zhiping, Karki, Rajendra, Malik, Ankit, Sharma, Deepika, Li, Liyuan, Malireddi, R.K. Subbarao, Gurung, Prajwal, Neale, Geoffrey, Olsen, Scott R., Carter, Robert A., McGoldrick, Daniel J., Wu, Gang, Finkelstein, David, Vogel, Peter, Gilbertson, Richard J., Kanneganti, Thirumala-Devi

“…Colorectal cancer is a leading cause of cancer-related deaths. Mutations in the innate immune sensor AIM2 are frequently identified in patients with colorectal…”
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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer by Malik, Ankit, Sharma, Deepika, Malireddi, R.K. Subbarao, Guy, Clifford S., Chang, Ti-Cheng, Olsen, Scott R., Neale, Geoffrey, Vogel, Peter, Kanneganti, Thirumala-Devi

“…Fungi represent a significant proportion of the gut microbiota. Aberrant immune responses to fungi are frequently observed in inflammatory bowel diseases (IBD)…”
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QUOKKA, the pinhole small‐angle neutron scattering instrument at the OPAL Research Reactor, Australia: design, performance, operation and scientific highlights by Wood, Kathleen, Mata, Jitendra P., Garvey, Christopher J., Wu, Chun-Ming, Hamilton, William A., Abbeywick, Peter, Bartlett, Daniel, Bartsch, Friedl, Baxter, Peter, Booth, Norman, Brown, Warren, Christoforidis, Jason, Clowes, Douglas, d'Adam, Timothy, Darmann, Frank, Deura, Michael, Harrison, Shane, Hauser, Nick, Horton, Glen, Federici, David, Franceschini, Ferdi, Hanson, Philip, Imamovic, Eno, Imperia, Paolo, Jones, Martin, Kennedy, Shane, Kim, Sungjoong, Lam, Tony, Lee, Wai Tung, Lesha, Mark, Mannicke, David, Noakes, Terry, Olsen, Scott R., Osborn, John C., Penny, David, Perry, Merv, Pullen, Stewart A., Robinson, Robert A., Schulz, Jamie C., Xiong, Norman, Gilbert, Elliot P.

“…QUOKKA is a 40 m pinhole small‐angle neutron scattering instrument in routine user operation at the OPAL research reactor at the Australian Nuclear Science and…”
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SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells by Minervina, Anastasia A., Pogorelyy, Mikhail V., Kirk, Allison M., Crawford, Jeremy Chase, Allen, E. Kaitlynn, Chou, Ching-Heng, Mettelman, Robert C., Allison, Kim J., Lin, Chun-Yang, Brice, David C., Zhu, Xun, Vegesana, Kasi, Wu, Gang, Trivedi, Sanchit, Kottapalli, Pratibha, Darnell, Daniel, McNeely, Suzanne, Olsen, Scott R., Schultz-Cherry, Stacey, Estepp, Jeremie H., McGargill, Maureen A., Wolf, Joshua, Thomas, Paul G.

“…Although mRNA vaccine efficacy against severe coronavirus disease 2019 remains high, variant emergence has prompted booster immunizations. However, the effects…”
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Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs by Dobson, Stephanie M, García-Prat, Laura, Vanner, Robert J, Wintersinger, Jeffrey, Waanders, Esmé, Gu, Zhaohui, McLeod, Jessica, Gan, Olga I, Grandal, Ildiko, Payne-Turner, Debbie, Edmonson, Michael N, Ma, Xiaotu, Fan, Yiping, Voisin, Veronique, Chan-Seng-Yue, Michelle, Xie, Stephanie Z, Hosseini, Mohsen, Abelson, Sagi, Gupta, Pankaj, Rusch, Michael, Shao, Ying, Olsen, Scott R, Neale, Geoffrey, Chan, Steven M, Bader, Gary, Easton, John, Guidos, Cynthia J, Danska, Jayne S, Zhang, Jinghui, Minden, Mark D, Morris, Quaid, Mullighan, Charles G, Dick, John E

“…Disease recurrence causes significant mortality in B-progenitor acute lymphoblastic leukemia (B-ALL). Genomic analysis of matched diagnosis and relapse samples…”
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Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages by Wilson, Taylor L, Kim, Hyunjin, Chou, Ching-Heng, Langfitt, Deanna, Mettelman, Robert C, Minervina, Anastasia A, Allen, E Kaitlynn, Métais, Jean-Yves, Pogorelyy, Mikhail V, Riberdy, Janice M, Velasquez, M Paulina, Kottapalli, Pratibha, Trivedi, Sanchit, Olsen, Scott R, Lockey, Timothy, Willis, Catherine, Meagher, Michael M, Triplett, Brandon M, Talleur, Aimee C, Gottschalk, Stephen, Crawford, Jeremy Chase, Thomas, Paul G

“…Current chimeric antigen receptor-modified (CAR) T-cell products are evaluated in bulk, without assessing functional heterogeneity. We therefore generated a…”
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Emergence of Polyclonal FLT3 Tyrosine Kinase Domain Mutations during Sequential Therapy with Sorafenib and Sunitinib in FLT3-ITD―Positive Acute Myeloid Leukemia by BAKER, Sharyn D, ZIMMERMAN, Eric I, RUBNITZ, Jeffrey E, MULLIGHAN, Charles G, INABA, Hiroto, WANG, Yong-Dong, ORWICK, Shelley, ZATECHKA, Douglas S, BUABOONNAM, Jassada, NEALE, Geoffrey A, OLSEN, Scott R, ENEMARK, Eric J, SHURTLEFF, Sheila

“…To evaluate the clinical activity of sequential therapy with sorafenib and sunitinib in FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication…”
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HTS 5 Tesla Synchrotron and Neutron Beamline Magnets by Pooke, D.M., Chamritski, V., Fee, M., Gibson, S., King, B.T., Tallon, J.L., Meissner, M., Feyerherm, R., Olsen, S.R., Kennedy, S.J., Robinson, R.A.

“…Two world-first High-Tc Superconducting (HTS) beamline magnets have been designed, manufactured and commissioned for synchrotron and neutron research…”
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The genomic landscape of juvenile myelomonocytic leukemia by Stieglitz, Elliot, Taylor-Weiner, Amaro N, Chang, Tiffany Y, Gelston, Laura C, Wang, Yong-Dong, Mazor, Tali, Esquivel, Emilio, Yu, Ariel, Seepo, Sara, Olsen, Scott R, Rosenberg, Mara, Archambeault, Sophie L, Abusin, Ghada, Beckman, Kyle, Brown, Patrick A, Briones, Michael, Carcamo, Benjamin, Cooper, Todd, Dahl, Gary V, Emanuel, Peter D, Fluchel, Mark N, Goyal, Rakesh K, Hayashi, Robert J, Hitzler, Johann, Hugge, Christopher, Liu, Y Lucy, Messinger, Yoav H, Mahoney, Donald H, Monteleone, Philip, Nemecek, Eneida R, Roehrs, Philip A, Schore, Reuven J, Stine, Kimo C, Takemoto, Clifford M, Toretsky, Jeffrey A, Costello, Joseph F, Olshen, Adam B, Stewart, Chip, Li, Yongjin, Ma, Jing, Gerbing, Robert B, Alonzo, Todd A, Getz, Gad, Gruber, Tanja A, Golub, Todd R, Stegmaier, Kimberly, Loh, Mignon L

“…Elliot Stieglitz, Mignon Loh and colleagues report the whole-exome sequencing of diagnostic and relapsed samples from patients with juvenile myelomonocytic…”
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Mutational Landscape and Patterns of Clonal Evolution in Relapsed Pediatric Acute Lymphoblastic Leukemia by Waanders, Esmé, Gu, Zhaohui, Dobson, Stephanie M., Antić, Željko, Crawford, Jeremy Chase, Ma, Xiaotu, Edmonson, Michael N., Payne-Turner, Debbie, van de Vorst, Maartje, Jongmans, Marjolijn C.J., McGuire, Irina, Zhou, Xin, Wang, Jian, Shi, Lei, Pounds, Stanley, Pei, Deqing, Cheng, Cheng, Song, Guangchun, Fan, Yiping, Shao, Ying, Rusch, Michael, McCastlain, Kelly, Yu, Jiangyan, van Boxtel, Ruben, Blokzijl, Francis, Iacobucci, Ilaria, Roberts, Kathryn G., Wen, Ji, Wu, Gang, Ma, Jing, Easton, John, Neale, Geoffrey, Olsen, Scott R., Nichols, Kim E., Pui, Ching-Hon, Zhang, Jinghui, Evans, William E., Relling, Mary V., Yang, Jun J., Thomas, Paul G., Dick, John E., Kuiper, Roland P., Mullighan, Charles G.

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Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia by Waanders, Esmé, Gu, Zhaohui, Dobson, Stephanie M, Antić, Željko, Crawford, Jeremy Chase, Ma, Xiaotu, Edmonson, Michael N, Payne-Turner, Debbie, van de Vorst, Maartje, Jongmans, Marjolijn C J, McGuire, Irina, Zhou, Xin, Wang, Jian, Shi, Lei, Pounds, Stanley, Pei, Deqing, Cheng, Cheng, Song, Guangchun, Fan, Yiping, Shao, Ying, Rusch, Michael, McCastlain, Kelly, Yu, Jiangyan, van Boxtel, Ruben, Blokzijl, Francis, Iacobucci, Ilaria, Roberts, Kathryn G, Wen, Ji, Wu, Gang, Ma, Jing, Easton, John, Neale, Geoffrey, Olsen, Scott R, Nichols, Kim E, Pui, Ching-Hon, Zhang, Jinghui, Evans, William E, Relling, Mary V, Yang, Jun J, Thomas, Paul G, Dick, John E, Kuiper, Roland P, Mullighan, Charles G

“…Relapse of acute lymphoblastic leukemia (ALL) remains a leading cause of childhood death. Prior studies have shown clonal mutations at relapse often arise from…”
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Correction: Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia by Stieglitz, Elliot, Taylor-Weiner, Amaro N, Chang, Tiffany Y, Gelston, Laura C, Wang, Yong-Dong, Mazor, Tali, Esquivel, Emilio, Yu, Ariel, Seepo, Sara, Olsen, Scott R, Rosenberg, Mara, Archambeault, Sophie L, Abusin, Ghada, Beckman, Kyle, Brown, Patrick A, Briones, Michael, Carcamo, Benjamin, Cooper, Todd, Dahl, Gary V, Emanuel, Peter D, Fluchel, Mark N, Goyal, Rakesh K, Hayashi, Robert J, Hitzler, Johann, Hugge, Christopher, Liu, Y Lucy, Messinger, Yoav H, Mahoney, Donald H, Monteleone, Philip, Nemecek, Eneida R, Roehrs, Philip A, Schore, Reuven J, Stine, Kimo C, Takemoto, Clifford M, Toretsky, Jeffrey A, Costello, Joseph F, Olshen, Adam B, Stewart, Chip, Li, Yongjin, Ma, Jing, Gerbing, Robert B, Alonzo, Todd A, Getz, Gad, Gruber, Tanja A, Golub, Todd R, Stegmaier, Kimberly, Loh, Mignon L

“…Nat. Genet. 47, 1326–1333 (2015); published online 12 October 2015; corrected after print 7 December 2015 In the version of this article initially published,…”
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Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia by Stieglitz, Elliot, Taylor-Weiner, Amaro N, Chang, Tiffany Y, Gelston, Laura C, Wang, Yong-Dong, Mazor, Tali, Esquivel, Emilio, Yu, Ariel, Seepo, Sara, Olsen, Scott R, Rosenberg, Mara, Archambeault, Sophie L, Abusin, Ghada, Beckman, Kyle, Brown, Patrick A, Briones, Michael, Carcamo, Benjamin, Cooper, Todd, Dahl, Gary V, Emanuel, Peter D, Fluchel, Mark N, Goyal, Rakesh K, Hayashi, Robert J, Hitzler, Johann, Hugge, Christopher, Liu, Y Lucy, Messinger, Yoav H, Mahoney, Jr, Donald H, Monteleone, Philip, Nemecek, Eneida R, Roehrs, Philip A, Schore, Reuven J, Stine, Kimo C, Takemoto, Clifford M, Toretsky, Jeffrey A, Costello, Joseph F, Olshen, Adam B, Stewart, Chip, Li, Yongjin, Ma, Jing, Gerbing, Robert B, Alonzo, Todd A, Getz, Gad, Gruber, Tanja A, Golub, Todd R, Stegmaier, Kimberly, Loh, Mignon L

“…Genet. 47, 1326-1333 (2015); published online 12 October 2015; corrected after print 7 December 2015 In the version of this article initially published, two…”
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