Search Results - "Olsen, Niels V"
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Acute hypoxia increases the cerebral metabolic rate – a magnetic resonance imaging study
Published in Journal of cerebral blood flow and metabolism (01-06-2016)“…The aim of the present study was to examine changes in cerebral metabolism by magnetic resonance imaging of healthy subjects during inhalation of 10% O2…”
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The age‐related reduction in cerebral blood flow affects vertebral artery more than internal carotid artery blood flow
Published in Clinical physiology and functional imaging (01-07-2019)“…Summary Ageing reduces cerebral blood flow (CBF), while mean arterial pressure (MAP) becomes elevated. According to ‘the selfish brain’ hypothesis of…”
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Influence of blood pressure on internal carotid artery blood flow during combined propofol-remifentanil and thoracic epidural anesthesia
Published in Journal of anaesthesiology, clinical pharmacology (01-10-2022)“…Background and Aims: Anesthesia often reduces mean arterial pressure (MAP) to a level that may compromise cerebral blood flow. We evaluated whether…”
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Central Nervous System Frontiers for the Use of Erythropoietin
Published in Clinical infectious diseases (15-11-2003)“…Recombinant human erythropoietin (r-HuEPO; epoetin alfa) is well established as safe and effective for the treatment of anemia. In addition to the…”
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Eighteen days of "living high, training low" stimulate erythropoiesis and enhance aerobic performance in elite middle-distance runners
Published in Journal of applied physiology (1985) (01-01-2006)“…1 Université Paris 13, Laboratoire "Réponses cellulaires et fonctionnelles à l'hypoxie," Bobigny; 2 Centre National de Ski Nordique, Prémanon; 3 Ecole…”
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6
Recombinant erythropoietin acutely decreases renal perfusion and decouples the renin‐angiotensin‐aldosterone system
Published in Physiological reports (01-03-2018)“…The effect of recombinant erythropoietin (rhEPO) on renal and systemic hemodynamics was evaluated in a randomized double‐blinded, cross‐over study. Sixteen…”
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High-dose erythropoietin for tissue protection
Published in European journal of clinical investigation (01-12-2014)“…Background The discovery of potential anti‐apoptotic and cytoprotective effects of recombinant human erythropoietin (rHuEPO) has led to clinical trials…”
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Living high-training low: effect on erythropoiesis and maximal aerobic performance in elite Nordic skiers
Published in European journal of applied physiology (01-08-2006)“…The "living high-training low" model (Hi-Lo) may improve aerobic performance in athletes, and the main mechanism of this improvement is thought to be augmented…”
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No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult Danes
Published in PloS one (25-09-2009)“…Evidence regarding the association of variation within ADRB2, the gene encoding the beta-adrenergic receptor 2 (ADRB2) with obesity and hypertension is…”
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Living high-training low: effect on erythropoiesis and aerobic performance in highly-trained swimmers
Published in European journal of applied physiology (01-03-2006)“…The "living high-training low" model (LHTL), i.e., training in normoxia but sleeping/living in hypoxia, is designed to improve the athletes performance…”
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Interindividual and regional relationship between cerebral blood flow and glucose metabolism in the resting brain
Published in Journal of applied physiology (1985) (01-10-2018)“…Studies of the resting brain measurements of cerebral blood flow (CBF) show large interindividual and regional variability, but the metabolic basis of this…”
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The Gly16 Allele of the Gly16Arg Single-Nucleotide Polymorphism in the β2-Adrenergic Receptor Gene Augments Perioperative Use of Vasopressors: A Retrospective Cohort Study
Published in Anesthesia and analgesia (01-05-2016)“…BACKGROUND:Arterial hypotension is frequent in patients undergoing anesthesia and may aggravate the outcome. Common genetic variations may influence the…”
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Internal carotid artery blood flow is enhanced by elevating blood pressure during combined propofol-remifentanil and thoracic epidural anaesthesia: A randomised cross-over trial
Published in European journal of anaesthesiology (01-06-2020)“…BACKGROUNDAnaesthesia reduces mean arterial pressure (MAP), and to preserve organ perfusion, vasopressors are often used to maintain MAP above 60 mmHg…”
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ADRB2 gly16gly Genotype, Cardiac Output, and Cerebral Oxygenation in Patients Undergoing Anesthesia for Abdominal Aortic Aneurysm Surgery
Published in Anesthesia and analgesia (01-12-2016)“…BACKGROUND:Gly16arg polymorphism of the adrenergic β2-receptor is associated with the elevated cardiac output (Q) in healthy gly16-homozygotic subjects. We…”
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Lipopolysaccharide-induced acute renal failure in conscious rats: effects of specific phosphodiesterase type 3 and 4 inhibition
Published in The Journal of pharmacology and experimental therapeutics (01-10-2002)“…In conscious, chronically instrumented rats we examined 1) renal tubular functional changes involved in lipopolysaccharide (LPS)-induced acute renal failure;…”
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Hepatic erythropoietin response in cirrhosis
Published in Scandinavian journal of clinical and laboratory investigation (02-04-2016)“…Background Erythropoietin (EPO) is produced in the liver during fetal life, but after birth the production shifts to the kidneys. The liver maintains a…”
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Measurement of peripheral arterial tonometry in patients with diabetic foot ulcers during courses of hyperbaric oxygen treatment
Published in Diving and hyperbaric medicine (31-03-2020)“…Treatment of diabetic foot ulcers is complex and often protracted. Hyperbaric oxygen treatment (HBOT) improves wound healing in diabetic ulcers and serves as…”
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The Gly16 Allele of the G16R Single Nucleotide Polymorphism in the β2-Adrenergic Receptor Gene Augments the Glycemic Response to Adrenaline in Humans
Published in Frontiers in physiology (05-09-2017)“…Cerebral non-oxidative carbohydrate consumption may be driven by a β 2 -adrenergic mechanism. This study tested whether the 46G > A (G16R) single nucleotide…”
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G16R single nucleotide polymorphism but not haplotypes of the β(2)-adrenergic receptor gene alters cardiac output in humans
Published in Clinical science (1979) (01-08-2013)“…Variation in genes encoding the β(2)-adrenergic receptor (ADRB2) and angiotensin-converting enzyme (ACE) may influence Q (cardiac output). The 46G>A (G16R) SNP…”
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Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans
Published in The FASEB journal (01-03-2012)“…Administration of erythropoietin (EPO) has been linked to cerebrovascular events. EPO reduces vascular conductance, possibly because of the increase in…”
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