Search Results - "Olsen, Minna B"

92-LB: Safety, Tolerability, and Clinical Effects of ZP8396, a Novel Long-Acting Amylin Analog—A Single Ascending Dose Trial by OLSEN, MINNA B., HÖVELMANN, ULRIKE, GRIFFIN, JON, KNUDSEN, KIM M., JOHANSEN, THUE, KENDALL, DAVID, HEISE, TIM

“…ZP8396 is an amylin analog designed for once weekly dosing that has demonstrated the potential to reduce body weight and improve glycemia in animal models of…”
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335-OR: Dapiglutide, a Once-Weekly GLP-1R/GLP-2R Dual Agonist, Was Safe and Well Tolerated and Showed Dose-Dependent Body Weight Loss over Four Weeks in Healthy Subjects by OLSEN, MINNA B., HÖVELMANN, ULRIKE, GRIFFIN, JON, KNUDSEN, KIM M., ERIKSSON, PER-OLOF, AGERSNAP, MIKKEL A.

“…Dapiglutide is a first-in-class peptide with dual activity on the GLP-1 and GLP-2 receptors and with potential to treat several metabolic/gastrointestinal (GI)…”
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1668-P: Novel Once-Weekly Amylin Analog Petrelintide (ZP8396) Is Well Tolerated with Improved GI Tolerability after Multiple Dosing by Griffin, Jon, Hövelmann, Ulrike, Melgaard, Anita E, Macura, Stanislava, Hammer, Mette, Johansen, Thue, Olsen, Minna B

“…Petrelintide (ZP8396) has demonstrated potential to reduce body weight after single and multiple dosing (SD and MD) in humans. The tolerability of doses, with…”
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1685-P: Dapiglutide Is a Dual Agonist on Human GLP-1- and GLP-2-Receptors with a Biased and Prolonged Signaling Profile at the GLP-1R by Gjelstrup, Louise, Lundholt, Betina Kerstin, Larsen, Bjarne D, Johansen, Nicklas J, Olsen, Minna B, Mathiesen, Jesper M

“…Dapiglutide, a potential first-in-class therapy targeting obesity and low-grade inflammation, is designed for activating both GLP-1 and GLP-2 receptors. In a…”
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How few cancer cells can be detected by positron emission tomography? A frequent question addressed by an in vitro study by Fischer, Barbara M, Olsen, Minna W B, Ley, Carsten D, Klausen, Thomas L, Mortensen, Jann, Højgaard, Liselotte, Kristjansen, Paul E G

“…Positron emission tomography (PET) has gained widespread use in cancer diagnosis and treatment, but how many malignant cells are required for a tumour to be…”
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Angiopoietin-4 Inhibits Angiogenesis and Reduces Interstitial Fluid Pressure by Olsen, Minna W.B., D. Ley, Carsten, Junker, Nanna, Hansen, Anker J., Lund, Eva L., Kristjansen, Paul E.G.

“…Angiopoietins (Ang) are involved in the remodeling, maturation, and stabilization of the vascular network. Ang-4 was discovered more recently; thus, its effect…”
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Differential regulation of VEGF, HIF1α and angiopoietin‐1, ‐2 and ‐4 by hypoxia and ionizing radiation in human glioblastoma by Lund, Eva L., Høg, Anja, Olsen, Minna W.B., Hansen, Lasse T., Engelholm, Svend A., Kristjansen, Paul E.G.

“…We examined how ionizing radiation (IR) delivered under either severe hypoxia (< 0.1% O2) or normoxia affects the expression of hypoxia inducible factor 1α…”
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Angiogenic synergy of bFGF and VEGF is antagonized by Angiopoietin-2 in a modified in vivo Matrigel assay by Ley, Carsten D., Olsen, Minna W.B., Lund, Eva L., Kristjansen, Paul E.G.

“…A murine modification of the Matrigel chamber assay originally developed for use on rats is presented. This modified assay permits improved quantification due…”
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Angiopoietin-4 Inhibits Angiogenesis and Reduces Interstitial Fluid Pressure1 by Olsen, Minna W B, Ley, Carsten D, Junker, Nanna, Hansen, Anker J, Lund, Eva L, Kristjansen, Paul E G

“…Angiopoietins (Ang) are involved in the remodeling, maturation, and stabilization of the vascular network. Ang-4 was discovered more recently; thus, its effect…”
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Differential regulation of VEGF, HIF1alpha and angiopoietin-1, -2 and -4 by hypoxia and ionizing radiation in human glioblastoma by Lund, Eva L, Høg, Anja, Olsen, Minna W B, Hansen, Lasse T, Engelholm, Svend A, Kristjansen, Paul E G

“…We examined how ionizing radiation (IR) delivered under either severe hypoxia (< 0.1% O2) or normoxia affects the expression of hypoxia inducible factor 1alpha…”
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Improved Effect of an Antiangiogenic Tyrosine Kinase Inhibitor (SU5416) by Combinations with Fractionated Radiotherapy or Low Molecular Weight Heparin by Lund, Eva L., Olsen, Minna W.B., Lipson, Kenneth E., McMahon, Gerald, Howlett, Anthony R., Kristjansen, Paul E.G.

“…The effect of combining SU5416 with fractionated radiotherapy or with low molecular weight (LMW) heparin (dalteparin) was studied in U87 human glioblastoma…”
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Improved Effect of an Antiangiogenic Tyrosine Kinase Inhibitor (SU5416) by Combinations with Fractionated Radiotherapy or Low Molecular Weight Heparin1 by Lund, Eva L, Olsen, Minna W B, Lipson, Kenneth E, McMahon, Gerald, Howlett, Anthony R, Kristjansen, Paul E G

“…The effect of combining SU5416 with fractionated radiotherapy or with low molecular weight (LMW) heparin (dalteparin) was studied in U87 human glioblastoma…”
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