Search Results - "Olofsson, Tor"
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Predictors of unacceptable pain with and without low inflammation over 5 years in early rheumatoid arthritis—an inception cohort study
Published in Arthritis research & therapy (14-06-2021)“…Abstract Objectives Pain is a major symptom in patients with rheumatoid arthritis (RA). In early RA, pain is usually due to synovitis, but can also persist…”
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Biological treatment of ankylosing spondylitis: a nationwide study of treatment trajectories on a patient level in clinical practice
Published in Arthritis research & therapy (28-05-2019)“…There is substantial evidence that patients with ankylosing spondylitis (AS) have high response rates to tumour necrosis factor inhibitors (TNFi), a low…”
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Gut dysbiosis associated with worse disease activity and physical function in axial spondyloarthritis
Published in Arthritis research & therapy (12-02-2022)“…Based on clinical and genetic associations, axial spondyloarthritis (axSpA) and inflammatory bowel disease (IBD) are suspected to have a linked pathogenesis…”
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Radiographic damage in early rheumatoid arthritis is associated with increased disability but not with pain-a 5-year follow-up study
Published in Arthritis research & therapy (27-02-2023)“…To evaluate how radiographic damage, overall and measured as joint space narrowing score (JSNS) and erosion score (ES), as well as other clinical and…”
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Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein
Published in Proceedings of the National Academy of Sciences - PNAS (14-09-2010)“…Chronic myeloid leukemia (CML) is genetically characterized by the Philadelphia (Ph) chromosome, formed through a reciprocal translocation between chromosomes…”
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Prime-boost vaccination strategy enhances immunogenicity compared to single pneumococcal conjugate vaccination in patients receiving conventional DMARDs, to some extent in abatacept but not in rituximab-treated patients
Published in Arthritis research & therapy (22-02-2020)“…To explore whether a prime-boost vaccination strategy, i.e., a dose of pneumococcal conjugate vaccine (PCV) and a dose of 23-valent polysaccharide vaccine…”
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Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort
Published in Annals of the rheumatic diseases (01-05-2014)“…To identify predictors of sick leave and disability pension in patients with early rheumatoid arthritis (RA). Individuals aged 19-59 years diagnosed with early…”
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Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation
Published in Blood (24-04-2014)“…In development, epigenetic mechanisms such as DNA methylation have been suggested to provide a cellular memory to maintain multipotency but also stabilize cell…”
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Correction to: Prime-boost vaccination strategy enhances immunogenicity compared to single pneumococcal conjugate vaccination in patients receiving conventional DMARDs, to some extent in abatacept but not in rituximab-treated patients
Published in Arthritis research & therapy (26-06-2020)“…An amendment to this paper has been published and can be accessed via the original article…”
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Treatment for Rheumatoid Arthritis Associated With Alterations in the Gastrointestinal Microbiota
Published in ACR open rheumatology (01-07-2024)“…Objective Emerging research suggests that rheumatoid arthritis (RA) is associated with intestinal dysbiosis. This prospective pilot study evaluates changes in…”
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Isolation and characterization of human myeloid progenitor populations—TpoR as discriminator between common myeloid and megakaryocyte/erythroid progenitors
Published in Experimental hematology (01-05-2006)“…The common myeloid progenitor (CMP) and its progeny, the granulocyte/monocyte progenitor (GMP) and megakaryocyte/erythrocyte progenitor (MEP), have been…”
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Does disease activity at start of biologic therapy influence work-loss in RA patients?
Published in Rheumatology (Oxford, England) (01-04-2016)“…To compare work-loss in RA patients starting their first biologic with high vs moderate disease activity. We identified all RA patients aged 20-63 years in the…”
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Methotrexate treatment in early psoriatic arthritis in comparison to rheumatoid arthritis: an observational nationwide study
Published in Rheumatic & musculoskeletal diseases open (01-05-2023)“…IntroductionWe aimed to compare the proportions of patients with newly diagnosed psoriatic arthritis (PsA) and rheumatoid arthritis (RA) remaining on…”
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Identification of a novel and myeloid specific role of the leukemia-associated fusion protein DEK-NUP214 leading to increased protein synthesis
Published in Genes chromosomes & cancer (01-04-2008)“…The t(6;9)(p22;q34) chromosomal translocation is found in a subset of patients with acute myeloid leukemia (AML). The translocation results in a fusion between…”
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Gene expression signatures in childhood acute leukemias are largely unique and distinct from those of normal tissues and other malignancies
Published in BMC medical genomics (08-03-2010)“…Childhood leukemia is characterized by the presence of balanced chromosomal translocations or by other structural or numerical chromosomal changes. It is well…”
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Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice
Published in Blood (23-09-2010)“…The 8p11 myeloproliferative syndrome (EMS), also referred to as stem cell leukemia/lymphoma, is a chronic myeloproliferative disorder that rapidly progresses…”
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Molecular Signatures in Childhood Acute Leukemia and Their Correlations to Expression Patterns in Normal Hematopoietic Subpopulations
Published in Proceedings of the National Academy of Sciences - PNAS (27-12-2005)“…Global expression profiles of a consecutive series of 121 childhood acute leukemias (87 B lineage acute lymphoblastic leukemias, 11 T cell acute lymphoblastic…”
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Tumor-Initiating Cells in Childhood Neuroblastoma-Letter
Published in Cancer research (Chicago, Ill.) (01-02-2012)Get full text
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Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of cytokine‐stimulated CD34+ human marrow cells in vitro
Published in British journal of haematology (01-11-2004)“…Summary With the objective to correlate clonogenicity, gene expression and phenotype during differentiation, human bone marrow CD34+ cells were cultured in…”
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Joint tenderness at 3 months follow-up better predicts long-term pain than baseline characteristics in early rheumatoid arthritis patients
Published in Rheumatology (Oxford, England) (01-03-2024)“…To investigate pain course over time and to identify baseline and 3-month predictors of unacceptable pain with or without low inflammation in early RA. A…”
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