Search Results - "Olmsted, Zachary T"

Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids by Olmsted, Zachary T., Paluh, Janet L.

“…Stem cell technologies including self-assembling 3D tissue models provide access to early human neurodevelopment and fundamental insights into…”
Get full text

A combined human gastruloid model of cardiogenesis and neurogenesis by Olmsted, Zachary T., Paluh, Janet L.

“…Multi-lineage development from gastruloids is enabling unprecedented opportunities to model and study human embryonic processes and is expected to accelerate…”
Get full text

Stem Cell Neurodevelopmental Solutions for Restorative Treatments of the Human Trunk and Spine by Olmsted, Zachary T, Paluh, Janet L

“…The ability to reliably repair spinal cord injuries (SCI) will be one of the greatest human achievements realized in regenerative medicine. Until recently, the…”
Get full text

Corrigendum: Axonal transport during injury on a theoretical axon by Chandra, Soumyadeep, Chatterjee, Rounak, Olmsted, Zachary T, Mukherjee, Amitava, Paluh, Janet L

“…[This corrects the article DOI: 10.3389/fncel.2023.1215945.]…”
Get full text

Axonal transport during injury on a theoretical axon by Chandra, Soumyadeep, Chatterjee, Rounak, Olmsted, Zachary T, Mukherjee, Amitava, Paluh, Janet L

“…Neurodevelopment, plasticity, and cognition are integral with functional directional transport in neuronal axons that occurs along a unique network of…”
Get full text

Fully Characterized Mature Human iPS- and NMP-Derived Motor Neurons Thrive Without Neuroprotection in the Spinal Contusion Cavity by Olmsted, Zachary T, Stigliano, Cinzia, Marzullo, Brandon, Cibelli, Jose, Horner, Philip J, Paluh, Janet L

“…Neural cell interventions in spinal cord injury (SCI) have focused predominantly on transplanted multipotent neural stem/progenitor cells (NSPCs) for animal…”
Get full text

Generation of human elongating multi-lineage organized cardiac gastruloids by Olmsted, Zachary T., Paredes-Espinosa, Maria Belen, Paluh, Janet L.

“…Human elongating multi-lineage organized (EMLOC) gastruloid technology captures key aspects of trunk neurodevelopment including neural integration with…”
Get full text

Review of the Treatments for Central Neuropathic Pain by Sheldon, Breanna L, Olmsted, Zachary T, Sabourin, Shelby, Heydari, Ehsaun, Harland, Tessa A, Pilitsis, Julie G

“…Central neuropathic pain (CNP) affects millions worldwide, with an estimated prevalence of around 10% globally. Although there are a wide variety of treatment…”
Get full text

Direct Wave Intraoperative Neuromonitoring for Spinal Tumor Resection: A Focused Review by Olmsted, Zachary T., Ryu, Brendan, Phayal, Ganesh, Green, Ross, Lo, Sheng-Fu Larry, Sciubba, Daniel M., Silverstein, Justin W., D’Amico, Randy S.

“…At present, surgical resection of primary intramedullary spinal cord tumors is the mainstay of treatment. However, given the dimensional constraints of the…”
Get full text

Recommendations for Neuromodulation in Diabetic Neuropathic Pain by Olmsted, Zachary T, Hadanny, Amir, Marchese, Anthony M, DiMarzio, Marisa, Khazen, Olga, Argoff, Charles, Sukul, Vishad, Pilitsis, Julie G

“…Over 50% of the 34 million people who suffer from diabetes mellitus (DM) are affected by diabetic neuropathy. Painful diabetic neuropathy (PDN) impacts 40-50%…”
Get full text

Transplantable human motor networks as a neuron-directed strategy for spinal cord injury by Olmsted, Zachary T., Stigliano, Cinzia, Scimemi, Annalisa, Wolfe, Tatiana, Cibelli, Jose, Horner, Philip J., Paluh, Janet L.

“…To repair neural circuitry following spinal cord injury (SCI), neural stem cell (NSC) transplantation has held a primary focus; however, stochastic outcomes…”
Get full text

Embryonic Spinal Cord Innervation in Human Trunk Organogenesis Gastruloids: Cardiac Versus Enteric Customization and Beyond by Olmsted, Zachary T, Paredes-Espinosa, Maria Belen, Paluh, Janet L

“…Trunk-biased human gastruloids provide the ability to couple developmentally relevant spinal neurogenesis and organ morphogenesis via spatiotemporal…”
Get more information

Intraoperative Monitoring of the External Urethral Sphincter Reflex: A Novel Adjunct to Bulbocavernosus Reflex Neuromonitoring for Protecting the Sacral Neural Pathways Responsible for Urination, Defecation and Sexual Function by Silverstein, Justin W, Block, Jon, Olmsted, Zachary T, Green, Ross, Pieters, Thomas, Babarevech, Kristiana, Ballas-Williamson, Alicia, Skinner, Stanley A, Sciubba, Daniel M, Larry Lo, Sheng-Fu

“…Intraoperative bulbocavernosus reflex neuromonitoring has been utilized to protect bowel, bladder, and sexual function, providing a continuous functional…”
Get full text

Preoperative evaluation of coagulation status in neuromodulation patients by Hadanny, Amir, Olmsted, Zachary T, Marchese, Anthony M, Kroll, Kyle, Figueroa, Christopher, Tagney, Thomas, Tram, Jennifer, DiMarzio, Marisa, Khazen, Olga, Mitchell, Dorothy, Cangero, Theodore, Sukul, Vishad, Pilitsis, Julie G

“…The incidence of hemorrhage in patients who undergo deep brain stimulation (DBS) and spinal cord stimulation (SCS) is between 0.5% and 2.5%. Coagulation status…”
Get full text

Kinesin-14 and kinesin-5 antagonistically regulate microtubule nucleation by γ-TuRC in yeast and human cells by Olmsted, Zachary T., Colliver, Andrew G., Riehlman, Timothy D., Paluh, Janet L.

“…Bipolar spindle assembly is a critical control point for initiation of mitosis through nucleation and organization of spindle microtubules and is regulated by…”
Get full text

Enhanced Recovery After Surgery (ERAS) for Cranial Tumor Resection: A Review by Greisman, Jacob D., Olmsted, Zachary T., Crorkin, Patrick J., Dallimore, Colin A., Zhigin, Vadim, Shlifer, Artur, Bedi, Anupama D., Kim, Jane K., Nelson, Priscilla, Sy, Heustein L., Patel, Kiran V., Ellis, Jason A., Boockvar, John, Langer, David J., D’Amico, Randy S.

“…Enhanced Recovery After Surgery (ERAS) protocols describe a standardized method of preoperative, perioperative, and postoperative care to enhance outcomes and…”
Get full text

Treatment Strategies for Generator Pocket Pain by Bao, Jonathan, Khazen, Olga, Olmsted, Zachary T, Gechtman, Guy, Shao, Miriam M, DiMarzio, Marisa, Topp, Gregory, Sukul, Vishad V, Staudt, Michael D, Pilitsis, Julie G

“…Abstract Objective Generator site pain is a relatively common phenomenon in patients undergoing spinal cord stimulation (SCS) that complicates management and…”
Get full text

Evolution of flash visual evoked potentials to monitor visual pathway integrity during tumor resection: illustrative cases and literature review by Olmsted, Zachary T., Silverstein, Justin W., Einstein, Evan H., Sowulewski, Jayne, Nelson, Priscilla, Boockvar, John A., D’Amico, Randy S.

“…Flash visual evoked potentials (fVEPs) provide a means to interrogate visual system functioning intraoperatively during tumor resection in which the optic…”
Get full text

Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery by Olmsted, Zachary T., Stigliano, Cinzia, Badri, Abinaya, Zhang, Fuming, Williams, Asher, Koffas, Mattheos A. G., Xie, Yubing, Linhardt, Robert J., Cibelli, Jose, Horner, Philip J., Paluh, Janet L.

“…Cell therapy for the injured spinal cord will rely on combined advances in human stem cell technologies and delivery strategies. Here we encapsulate homotypic…”
Get full text

Derivation of Ethnically Diverse Human Induced Pluripotent Stem Cell Lines by Chang, Eun Ah, Tomov, Martin L., Suhr, Steven T., Luo, Jiesi, Olmsted, Zachary T., Paluh, Janet L., Cibelli, Jose

“…The human genome with all its ethnic variations contributes to differences in human development, aging, disease, repair and response to medical treatments and…”
Get full text