Search Results - "Ollila, O. H. Samuli"

Interfacial Tension and Surface Pressure of High Density Lipoprotein, Low Density Lipoprotein, and Related Lipid Droplets by Ollila, O. H. Samuli, Lamberg, Antti, Lehtivaara, Maria, Koivuniemi, Artturi, Vattulainen, Ilpo

“…Lipid droplets play a central role in energy storage and metabolism on a cellular scale. Their core is comprised of hydrophobic lipids covered by a surface…”
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Acyl Chain Disorder and Azelaoyl Orientation in Lipid Membranes Containing Oxidized Lipids by Mendes Ferreira, Tiago, Sood, Rohit, Bärenwald, Ruth, Carlström, Göran, Topgaard, Daniel, Saalwächter, Kay, Kinnunen, Paavo K. J, Ollila, O. H. Samuli

“…Oxidized phospholipids occur naturally in conditions of oxidative stress and have been suggested to play an important role in a number of pathological…”
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The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms by Beyer, Hannes M, Virtanen, Salla I, Aranko, A Sesilja, Mikula, Kornelia M, Lountos, George T, Wlodawer, Alexander, Ollila, O H Samuli, Iwaï, Hideo

“…Protein splicing catalyzed by inteins utilizes many different combinations of amino-acid types at active sites. Inteins have been classified into three classes…”
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NMR Structure and Dynamics of TonB Investigated by Scar-Less Segmental Isotopic Labeling Using a Salt-Inducible Split Intein by Ciragan, Annika, Backlund, Sofia M, Mikula, Kornelia M, Beyer, Hannes M, Samuli Ollila, O H, Iwaï, Hideo

“…The growing understanding of partially unfolded proteins increasingly points to their biological relevance in allosteric regulation, complex formation, and…”
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Rotational Diffusion of Membrane Proteins in Crowded Membranes by Javanainen, Matti, Ollila, O. H. Samuli, Martinez-Seara, Hector

“…Membrane proteins travel along cellular membranes and reorient themselves to form functional oligomers and protein–lipid complexes. Following the…”
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Headgroup Structure and Cation Binding in Phosphatidylserine Lipid Bilayers by Antila, Hanne, Buslaev, Pavel, Favela-Rosales, Fernando, Ferreira, Tiago M, Gushchin, Ivan, Javanainen, Matti, Kav, Batuhan, Madsen, Jesper J, Melcr, Josef, Miettinen, Markus S, Määttä, Jukka, Nencini, Ricky, Ollila, O. H. Samuli, Piggot, Thomas J

“…Phosphatidylserine (PS) is a negatively charged lipid type commonly found in eukaryotic membranes, where it interacts with proteins via nonspecific…”
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Rotational Dynamics of Proteins from Spin Relaxation Times and Molecular Dynamics Simulations by Ollila, O. H. Samuli, Heikkinen, Harri A, Iwaï, Hideo

“…Conformational fluctuations and rotational tumbling of proteins can be experimentally accessed with nuclear spin relaxation experiments. However,…”
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Toward Atomistic Resolution Structure of Phosphatidylcholine Headgroup and Glycerol Backbone at Different Ambient Conditions by Botan, Alexandru, Favela-Rosales, Fernando, Fuchs, Patrick F. J, Javanainen, Matti, Kanduč, Matej, Kulig, Waldemar, Lamberg, Antti, Loison, Claire, Lyubartsev, Alexander, Miettinen, Markus S, Monticelli, Luca, Määttä, Jukka, Ollila, O. H. Samuli, Retegan, Marius, Róg, Tomasz, Santuz, Hubert, Tynkkynen, Joona

“…Phospholipids are essential building blocks of biological membranes. Despite a vast amount of very accurate experimental data, the atomistic resolution…”
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Inverse Conformational Selection in Lipid–Protein Binding by Bacle, Amélie, Buslaev, Pavel, Garcia-Fandino, Rebeca, Favela-Rosales, Fernando, Mendes Ferreira, Tiago, Fuchs, Patrick F. J, Gushchin, Ivan, Javanainen, Matti, Kiirikki, Anne M, Madsen, Jesper J, Melcr, Josef, Milán Rodríguez, Paula, Miettinen, Markus S, Ollila, O. H. Samuli, Papadopoulos, Chris G, Peón, Antonio, Piggot, Thomas J, Piñeiro, Ángel, Virtanen, Salla I

“…Interest in lipid interactions with proteins and other biomolecules is emerging not only in fundamental biochemistry but also in the field of nanobiotechnology…”
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Overlay databank unlocks data-driven analyses of biomolecules for all by Kiirikki, Anne M., Antila, Hanne S., Bort, Lara S., Buslaev, Pavel, Favela-Rosales, Fernando, Ferreira, Tiago Mendes, Fuchs, Patrick F. J., Garcia-Fandino, Rebeca, Gushchin, Ivan, Kav, Batuhan, Kučerka, Norbert, Kula, Patrik, Kurki, Milla, Kuzmin, Alexander, Lalitha, Anusha, Lolicato, Fabio, Madsen, Jesper J., Miettinen, Markus S., Mingham, Cedric, Monticelli, Luca, Nencini, Ricky, Nesterenko, Alexey M., Piggot, Thomas J., Piñeiro, Ángel, Reuter, Nathalie, Samantray, Suman, Suárez-Lestón, Fabián, Talandashti, Reza, Ollila, O. H. Samuli

“…Tools based on artificial intelligence (AI) are currently revolutionising many fields, yet their applications are often limited by the lack of suitable…”
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Heterogeneous dynamics in partially disordered proteins by Virtanen, Salla I, Kiirikki, Anne M, Mikula, Kornelia M, Iwaï, Hideo, Ollila, O H Samuli

“…Importance of disordered protein regions is increasingly recognized in biology, but their characterization remains challenging due to the lack of suitable…”
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Can pyrene probes be used to measure lateral pressure profiles of lipid membranes? Perspective through atomistic simulations by Dékány Fraňová, Miroslava, Vattulainen, Ilpo, Samuli Ollila, O.H.

“…The lateral pressure profile of lipid bilayers has gained a lot of attention, since changes in the pressure profile have been suggested to shift the membrane…”
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Probing the dynamic landscape of peptides in molecular assemblies by synergized NMR experiments and MD simulations by Nencini, Ricky, Regnier, Morgan L. G., Backlund, Sofia M., Mantzari, Efstathia, Dunn, Cory D., Ollila, O. H. Samuli

“…Peptides or proteins containing small biomolecular aggregates, such as micelles, bicelles, droplets and nanodiscs, are pivotal in many fields ranging from…”
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Role of sterol type on lateral pressure profiles of lipid membranes affecting membrane protein functionality: Comparison between cholesterol, desmosterol, 7-dehydrocholesterol and ketosterol by Samuli Ollila, O.H., Róg, Tomasz, Karttunen, Mikko, Vattulainen, Ilpo

“…Lateral pressure profiles have been suggested to play a significant role in many cellular membrane processes by affecting, for example, the activation of…”
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NMR structure of the C-terminal domain of TonB protein from Pseudomonas aeruginosa by Oeemig, Jesper S, Ollila, O H Samuli, Iwaï, Hideo

“…The TonB protein plays an essential role in the energy transduction system to drive active transport across the outer membrane (OM) using the proton-motive…”
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Accurate Simulations of Lipid Monolayers Require a Water Model with Correct Surface Tension by Tempra, Carmelo, Ollila, O. H. Samuli, Javanainen, Matti

“…Lipid monolayers provide our lungs and eyes their functionality and serve as proxy systems in biomembrane research. Therefore, lipid monolayers have been…”
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Protein Shape Change Has a Major Effect on the Gating Energy of a Mechanosensitive Channel by Samuli Ollila, O.H., Louhivuori, Martti, Marrink, Siewert J., Vattulainen, Ilpo

“…Increasing experimental evidence has shown that membrane protein functionality depends on molecular composition of cell membranes. However, the origin of this…”
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Accurate Binding of Sodium and Calcium to a POPC Bilayer by Effective Inclusion of Electronic Polarization by Melcr, Josef, Martinez-Seara, Hector, Nencini, Ricky, Kolafa, Jiří, Jungwirth, Pavel, Ollila, O. H. Samuli

“…Binding affinities and stoichiometries of Na+ and Ca2+ ions to phospholipid bilayers are of paramount significance in the properties and functionality of…”
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Charged Small Molecule Binding to Membranes in MD Simulations Evaluated against NMR Experiments by Nencini, Ricky, Ollila, O. H. Samuli

“…Interactions of charged molecules with biomembranes regulate many of their biological activities, but their binding affinities to lipid bilayers are difficult…”
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Rapid Interpretation of Protein Backbone Rotation Dynamics Directly from Spin Relaxation Data by Nencini, Ricky, Mantzari, Efstathia, Sandelin, Amanda E., Ollila, O. H. Samuli

“…Besides their structure, dynamics is pivotal for protein functions, particularly for intrinsically disordered proteins (IDPs) that do not fold into a fixed 3D…”
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