Search Results - "Ollila, Hanna M."
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Genetics of 35 blood and urine biomarkers in the UK Biobank
Published in Nature genetics (01-02-2021)“…Clinical laboratory tests are a critical component of the continuum of care. We evaluate the genetic basis of 35 blood and urine laboratory measurements in the…”
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Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank
Published in PLoS medicine (12-10-2021)“…Sleep problems are both symptoms of and modifiable risk factors for many psychiatric disorders. Wrist-worn accelerometers enable objective measurement of sleep…”
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Genetic analysis of probable sleep bruxism and its associations with clinical and behavioral traits
Published in Sleep (New York, N.Y.) (01-10-2023)“…Abstract Study Objectives Sleep bruxism (SB) can cause damage on teeth, headache and severe pain affecting both sleep and daily functioning. Yet despite the…”
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Face masks to prevent transmission of respiratory infections: Systematic review and meta-analysis of randomized controlled trials on face mask use
Published in PloS one (01-12-2022)“…To examine the use of face mask intervention in mitigating the risk of spreading respiratory infections and whether the effect of face mask intervention…”
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Pandemic Dreams: Network Analysis of Dream Content During the COVID-19 Lockdown
Published in Frontiers in psychology (01-10-2020)“…We used crowdsourcing (CS) to examine how COVID-19 lockdown affects the content of dreams and nightmares. The CS took place on the sixth week of the lockdown…”
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Nightmares: Prevalence among the Finnish General Adult Population and War Veterans during 1972-2007
Published in Sleep (New York, N.Y.) (01-07-2013)“…To investigate the prevalence of nightmares among the Finnish general adult population during 1972-2007 and the association between nightmare prevalence and…”
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Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic
Published in PLoS genetics (01-10-2013)“…Previous studies in narcolepsy, an autoimmune disorder affecting hypocretin (orexin) neurons and recently associated with H1N1 influenza, have demonstrated…”
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8
Environmental stress affects DNA methylation of a CpG rich promoter region of serotonin transporter gene in a nurse cohort
Published in PloS one (28-09-2012)“…Shift-working nurses are exposed to a stressful work environment, which puts them at an increased risk for burnout and depression. We explored the effect of…”
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Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects
Published in BMC genomics (07-03-2024)“…Congenital heart defects (CHD) are structural defects of the heart affecting approximately 1% of newborns. They exhibit low penetrance and non-Mendelian…”
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10
HLA-DPB1 and HLA Class I Confer Risk of and Protection from Narcolepsy
Published in American journal of human genetics (08-01-2015)“…Type 1 narcolepsy, a disorder caused by a lack of hypocretin (orexin), is so strongly associated with human leukocyte antigen (HLA) class II…”
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SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease
Published in Nature communications (19-03-2024)“…Lyme disease is a tick-borne disease caused by bacteria of the genus Borrelia . The host factors that modulate susceptibility for Lyme disease have remained…”
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Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses
Published in Scientific reports (22-04-2016)“…Sleep loss and insufficient sleep are risk factors for cardiometabolic diseases, but data on how insufficient sleep contributes to these diseases are scarce…”
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13
Nightmares share genetic risk factors with sleep and psychiatric traits
Published in Translational psychiatry (27-02-2024)“…Nightmares are vivid, extended, and emotionally negative or negative dreams that awaken the dreamer. While sporadic nightmares and bad dreams are common and…”
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14
Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans
Published in PloS one (23-10-2013)“…Epidemiological studies have shown that short or insufficient sleep is associated with increased risk for metabolic diseases and mortality. To elucidate…”
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15
Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance
Published in PloS one (18-02-2010)“…Disturbances in the circadian pacemaker system are commonly found in individuals with depression and sleep-related problems. We hypothesized that some of the…”
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Causal Association Between Subtypes of Excessive Daytime Sleepiness and Risk of Cardiovascular Diseases
Published in Journal of the American Heart Association (19-12-2023)“…Excessive daytime sleepiness (EDS), experienced in 10% to 20% of the population, has been associated with cardiovascular disease and death. However, the…”
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Narcolepsy type 1: what have we learned from genetics?
Published in Sleep (New York, N.Y.) (01-11-2020)“…Abstract Type-1 narcolepsy is a severe neurological disorder with distinct characteristic of loss of hypocretin neurotransmitter. Genetic analysis in type-1…”
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Genome‐wide association study of sleep duration in the Finnish population
Published in Journal of sleep research (01-12-2014)“…Summary Sleep duration is genetically regulated, but the genetic variants are largely unknown. We aimed to identify such genes using a genome‐wide association…”
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Portability of Polygenic Risk Scores for Sleep Duration, Insomnia and Chronotype in 33,493 Individuals
Published in Clocks & Sleep (Online) (30-12-2022)“…Polygenic risk scores (PRSs) estimate genetic liability for diseases and traits. However, the portability of PRSs in sleep traits has remained elusive. We…”
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Mendelian randomization highlights insomnia as a risk factor for pain diagnoses
Published in Sleep (New York, N.Y.) (01-07-2021)“…Abstract Study Objective Insomnia has been linked to acute and chronic pain conditions; however, it is unclear whether such relationships are causal. Recently,…”
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