Search Results - "Olivotto, Eleonora"
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Inflammatory molecules produced by meniscus and synovium in early and end‐stage osteoarthritis: a coculture study
Published in Journal of cellular physiology (01-07-2019)“…The aim of this study was to identify the molecules and pathways involved in the cross‐talk between meniscus and synovium that may play a critical role in…”
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2
Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases
Published in Scientific reports (04-11-2021)“…IKKα and IKKβ are essential kinases for activating NF-κB transcription factors that regulate cellular differentiation and inflammation. By virtue of their…”
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3
Infrapatellar Fat Pad Gene Expression and Protein Production in Patients with and without Osteoarthritis
Published in International journal of molecular sciences (21-08-2020)“…Osteoarthritis (OA) is one of the most common joint disorders. Evidence suggests that the infrapatellar fat pad (IFP) is directly involved in OA pathology…”
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Do Synovial Inflammation and Meniscal Degeneration Impact Clinical Outcomes of Patients Undergoing Arthroscopic Partial Meniscectomy? A Histological Study
Published in International journal of molecular sciences (31-03-2022)“…The menisci exert a prominent role in joint stabilization and in the distribution of mechanical loading. Meniscal damage is associated with increased risk of…”
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5
Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1β-stimulated production of chemokines and matrix-degrading enzymes in vitro
Published in PloS one (12-05-2014)“…In osteoarthritis (OA), an inflammatory environment is responsible for the imbalance between the anabolic and catabolic activity of chondrocytes and, thus, for…”
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Morphological and ultrastructural analysis of normal, injured and osteoarthritic human knee menisci
Published in European journal of histochemistry (11-02-2019)“…The human meniscus plays a crucial role for transmission and distribution of load across the knee, as well as shock absorption, joint stability, lubrication,…”
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Operative versus nonoperative treatment in children with painful rigid flatfoot and talocalcaneal coalition
Published in BMC musculoskeletal disorders (24-03-2020)“…The management of painful rigid flatfoot (RFF) with talocalcaneal coalition (TCC) is controversial. We aimed to compare operative and nonoperative treatment in…”
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Quantitative MRI analysis of infrapatellar and suprapatellar fat pads in normal controls, moderate and end-stage osteoarthritis
Published in Annals of anatomy (01-01-2019)“…The aim of this study was to analyze the magnetic resonance imaging (MRI) volumetric and morphometric characteristics of the infrapatellar fat pad (IFP) and…”
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Deformity progression in congenital posteromedial bowing of the tibia: a report of 44 cases
Published in BMC musculoskeletal disorders (03-07-2020)“…congenital posteromedial bowing of tibia (CPMBT) is a very rare birth defect, characterized by shortened bowed leg and ankle deformity. We described a single…”
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Exploring Anatomo-Morphometric Characteristics of Infrapatellar, Suprapatellar Fat Pad, and Knee Ligaments in Osteoarthritis Compared to Post-Traumatic Lesions
Published in Biomedicines (09-06-2022)“…Several studies have investigated cartilage degeneration and inflammatory subchondral bone and synovial membrane changes using magnetic resonance (MR) in…”
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Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement
Published in Journal of orthopaedic surgery and research (28-02-2020)“…Hip osteoarthritis (HOA) is the most common hip disorder and a major cause of disability in the adult population, with an estimated prevalence of end-stage…”
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12
IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation
Published in PloS one (2013)“…The non-canonical NF-κB activating kinase IKKα, encoded by CHUK (conserved-helix-loop-helix-ubiquitous-kinase), has been reported to modulate pro- or anti-…”
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In Vitro Synovial Membrane 3D Model Developed by Volumetric Extrusion Bioprinting
Published in Applied sciences (01-02-2023)“…(1) Background: Synovial tissue plays a fundamental role in inflammatory processes. Therefore, understanding the mechanisms regulating healthy and diseased…”
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Age-Dependent Remodeling in Infrapatellar Fat Pad Adipocytes and Extracellular Matrix: A Comparative Study
Published in Frontiers in medicine (10-05-2021)“…The infrapatellar fat pad (IFP) is actively involved in knee osteoarthritis (OA). However, a proper description of which developmental modifications occur in…”
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Neglected Fractures of the Lateral Humeral Condyle in Children; Which Treatment for Which Condition?
Published in Children (Basel) (18-01-2021)“…Neglected fractures of the lateral humeral condyle (LHC) are misdiagnosed or insufficiently treated fractures, presenting later than 3 weeks after injury. The…”
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Good Subjective Outcomes, Stable Knee and High Return to Sport after Tibial Eminence Avulsion Fracture in Children
Published in Children (Basel) (01-10-2020)“…Avulsion fracture of the tibial spine (TSA) is uncommon in children, although its incidence is increasing with the earlier practice of competitive sport…”
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Response to "Letter to the editor: Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement"
Published in Journal of orthopaedic surgery and research (22-07-2020)“…[...]we acknowledge that the lack of samples of healthy controls is an important limitation to our paper. More importantly, as clearly stated in the abstract…”
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p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis
Published in Arthritis research & therapy (27-02-2014)“…Recent evidence suggests that tissue accumulation of senescent p16INK4a-positive cells during the life span would be deleterious for tissue functions and could…”
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156 MICROCRYSTALS IN THE SYNOVIAL FLUID OF PATIENTS WITH FEMOROACETABULAR IMPINGEMENT IMPACT ON CLINICAL OUTCOMES
Published in Osteoarthritis and cartilage (01-04-2024)Get full text
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Hip Labral Morphological Changes in Patients with Femoroacetabular Impingement Speed Up the Onset of Early Osteoarthritis
Published in Calcified tissue international (01-06-2023)“…Over the last decade, evidence has mounted for a prominent etiologic role of femoroacetabular impingement (FAI) in the development of early hip osteoarthritis…”
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