Search Results - "Olivieri, Kevin"

PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1 by Yoh, Sunnie M., Schneider, Monika, Seifried, Janna, Soonthornvacharin, Stephen, Akleh, Rana E., Olivieri, Kevin C., De Jesus, Paul D., Ruan, Chunhai, de Castro, Elisa, Ruiz, Pedro A., Germanaud, David, des Portes, Vincent, García-Sastre, Adolfo, König, Renate, Chanda, Sumit K.

“…Dendritic cells (DCs) play a critical role in the immune response to viral infection through the facilitation of cell-intrinsic antiviral activity and the…”
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Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation by Mukerji, Joya, Olivieri, Kevin C, Misra, Vikas, Agopian, Kristin A, Gabuzda, Dana

“…HIV-1 Nef protein contributes to pathogenesis via multiple functions that include enhancement of viral replication and infectivity, alteration of intracellular…”
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Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2 by Olivieri, Kevin C, Mukerji, Joya, Gabuzda, Dana

“…The HIV-1 accessory protein Nef is an important determinant of lentiviral pathogenicity that contributes to disease progression by enhancing viral replication…”
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Clade F AAVHSCs cross the blood brain barrier and transduce the central nervous system in addition to peripheral tissues following intravenous administration in nonhuman primates by Ellsworth, Jeff L, Gingras, Jacinthe, Smith, Laura J, Rubin, Hillard, Seabrook, Tania A, Patel, Kruti, Zapata, Nicole, Olivieri, Kevin, O'Callaghan, Michael, Chlipala, Elizabeth, Morales, Pablo, Seymour, Albert

“…The biodistribution of AAVHSC7, AAVHSC15, and AAVHSC17 following systemic delivery was assessed in cynomolgus macaques (Macaca fascicularis). Animals received…”
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Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu by Jain, Prashant, Boso, Guney, Langer, Simon, Soonthornvacharin, Stephen, De Jesus, Paul D., Nguyen, Quy, Olivieri, Kevin C., Portillo, Alex J., Yoh, Sunnie M., Pache, Lars, Chanda, Sumit K.

“…Accessory proteins of lentiviruses, such as HIV-1, target cellular restriction factors to enhance viral replication. Systematic analyses of proteins that are…”
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An integrated map of HIV-human protein complexes that facilitate viral infection by Emig-Agius, Dorothea, Olivieri, Kevin, Pache, Lars, Shih, Hsin Ling, Pustovalova, Olga, Bessarabova, Marina, Young, John A T, Chanda, Sumit K, Ideker, Trey

“…Recent proteomic and genetic studies have aimed to identify a complete network of interactions between HIV and human proteins and genes. This HIV-human…”
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Evidence for adaptive evolution at the divergence between lymphoid and brain HIV-1 nef genes by Olivieri, Kevin C, Agopian, Kristin A, Mukerji, Joya, Gabuzda, Dana

“…Human immunodeficiency virus type 1 (HIV) infection of the central nervous system frequently causes HIV-associated neurocognitive disorders (HAND). The role of…”
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Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142 by Olivieri, Kevin C, Scoggins, Robert M, Broderick, Brooks, Powell, Maria L C, Alexander, Melissa A, Hammarskjöld, Marie-Louise, Rekosh, David, Camerini, David

“…AIDS-associated, CCR5-tropic (R5) HIV-1 clones, isolated from a patient that never developed CXCR4-tropic HIV-1, replicate to a greater extent and cause…”
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HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3 by Manganaro, Lara, de Castro, Elisa, Maestre, Ana M, Olivieri, Kevin, García-Sastre, Adolfo, Fernandez-Sesma, Ana, Simon, Viviana

“…The accessory HIV protein Vpu inhibits a number of cellular pathways that trigger host innate restriction mechanisms. HIV Vpu-mediated degradation of tetherin…”
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Systematic analysis of T cell responses specific to the Epstein-Barr virus proteome using ATLAS by Kaufmann, Johanna K, Liu, Biao, Jacques, Judy, Wu, Ning, Yan, Zheng, Alami, Aula, Kelley, Christine, O’Keeffe, Michael S, Hoover, Maegan E, McManus, Margaret M, Henderson, Jennifer, Ghamsari, Lila, Olivieri, Kevin C, Flechtner, Jessica B, Broom, Wendy, Flano, Emilio, Luzuriaga, Katherine

“…Abstract Epstein-Barr virus (EBV) is a human herpesvirus infecting 95% of the world population. Primary infection can cause acute infectious mononucleosis…”
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Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection by Goujon, Caroline, Schaller, Torsten, Galão, Rui Pedro, Amie, Sarah M, Kim, Baek, Olivieri, Kevin, Neil, Stuart J D, Malim, Michael H

“…Type I interferon (IFN) treatment of some cells, including dendritic cells, macrophages and monocytic THP-1 cells, restricts HIV-1 infection and prevents viral…”
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Evidence for IFN[alpha]-induced, SAMHD1-independent inhibitors of early HIV-1 infection by Goujon, Caroline, Schaller, Torsten, Galão, Rui Pedro, Amie, Sarah M, Kim, Baek, Olivieri, Kevin, Neil, Stuart JD, Malim, Michael H

“…Background Type I interferon (IFN) treatment of some cells, including dendritic cells, macrophages and monocytic THP-1 cells, restricts HIV-1 infection and…”
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The envelope gene is a cytopathic determinant of CCR5 tropic HIV-1 by Olivieri, Kevin, Scoggins, Robert M, Bor, Yeou-cherng, Matthews, Aprille, Mark, David, Taylor, James R, Chernauskas, David, Hammarskjöld, Marie-Louise, Rekosh, David, Camerini, David

“…Abstract Late stage AIDS associated CCR5 tropic HIV-1 clones (R5-AIDS HIV-1) exhibit greater cytopathic effects (CPE) than earlier isolates from the same…”
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An Integrated Map of HIV-Human Protein Complexes that Facilitate Viral Infection: e96687 by Emig-Agius, Dorothea, Olivieri, Kevin, Pache, Lars, Shih, Hsin Ling, Pustovalova, Olga, Bessarabova, Marina, Young, John AT, Chanda, Sumit K, Ideker, Trey

“…Recent proteomic and genetic studies have aimed to identify a complete network of interactions between HIV and human proteins and genes. This HIV-human…”
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The contribution of Env and Nef to R5 AIDS HIV-1 replication by Olivieri, Kevin Charles

“…We had previously shown that CCR5 tropic (R5) HIV-1 clones obtained before the onset of AIDS (pre-AIDS clones) replicated less well and caused fewer cytopathic…”
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The contribution of Env and Nef to R5 AIDS HIV-1 replication by Olivieri, Kevin Charles

“…We had previously shown that CCR5 tropic (R5) HIV-1 clones obtained before the onset of AIDS (pre-AIDS clones) replicated less well and caused fewer cytopathic…”
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