Search Results - "Olivier Lespinet"
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1
Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation
Published in Nature communications (01-09-2021)“…Bacteria of the genus Streptomyces are prolific producers of specialized metabolites, including antibiotics. The linear chromosome includes a central region…”
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2
Survival trade-offs in plant roots during colonization by closely related beneficial and pathogenic fungi
Published in Nature communications (06-05-2016)“…The sessile nature of plants forced them to evolve mechanisms to prioritize their responses to simultaneous stresses, including colonization by microbes or…”
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3
On the predictibility of A-minor motifs from their local contexts
Published in RNA biology (31-12-2022)“…This study investigates the importance of the structural context in the formation of a type I/II A-minor motif. This very frequent structural motif has been…”
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4
The ribosome profiling landscape of yeast reveals a high diversity in pervasive translation
Published in Genome Biology (14-10-2024)“…Pervasive translation is a widespread phenomenon that plays a critical role in the emergence of novel microproteins, but the diversity of translation patterns…”
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5
Gapless genome assembly of Colletotrichum higginsianum reveals chromosome structure and association of transposable elements with secondary metabolite gene clusters
Published in BMC genomics (29-08-2017)“…The ascomycete fungus Colletotrichum higginsianum causes anthracnose disease of brassica crops and the model plant Arabidopsis thaliana. Previous versions of…”
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6
Comparative genomics of emerging pathogens in the Candida glabrata clade
Published in BMC genomics (14-09-2013)“…Candida glabrata follows C. albicans as the second or third most prevalent cause of candidemia worldwide. These two pathogenic yeasts are distantly related, C…”
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7
CusProSe: a customizable protein annotation software with an application to the prediction of fungal secondary metabolism genes
Published in Scientific reports (25-01-2023)“…We report here a new application, CustomProteinSearch (CusProSe), whose purpose is to help users to search for proteins of interest based on their domain…”
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FUNGIpath: a tool to assess fungal metabolic pathways predicted by orthology
Published in BMC genomics (01-02-2010)“…More and more completely sequenced fungal genomes are becoming available and many more sequencing projects are in progress. This deluge of data should improve…”
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The role of lineage-specific gene family expansion in the evolution of eukaryotes
Published in Genome research (01-07-2002)“…A computational procedure was developed for systematic detection of lineage-specific expansions (LSEs) of protein families in sequenced genomes and applied to…”
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Comparative Genomics among Closely Related Streptomyces Strains Revealed Specialized Metabolite Biosynthetic Gene Cluster Diversity
Published in Antibiotics (Basel) (02-10-2018)“…Specialized metabolites are of great interest due to their possible industrial and clinical applications. The increasing number of antimicrobial resistant…”
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11
ORENZA: a web resource for studying ORphan ENZyme activities
Published in BMC bioinformatics (06-10-2006)“…Despite the current availability of several hundreds of thousands of amino acid sequences, more than 36% of the enzyme activities (EC numbers) defined by the…”
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12
The New Animal Phylogeny: Reliability and Implications
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2000)“…DNA sequence analysis dictates new interpretation of phylogenic trees. Taxa that were once thought to represent successive grades of complexity at the base of…”
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13
Assessment of phylogenetic diversity of bacterial microflora in drinking water using serial analysis of ribosomal sequence tags
Published in Water research (Oxford) (01-09-2009)“…We examined chlorinated drinking water samples from three different surface water treatment plants for bacterial 16S rDNA diversity using the serial analysis…”
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14
Assessing the evolutionary rate of positional orthologous genes in prokaryotes using synteny data
Published in BMC evolutionary biology (29-11-2007)“…Comparison of completely sequenced microbial genomes has revealed how fluid these genomes are. Detecting synteny blocks requires reliable methods to…”
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15
Erratum: Survival trade-offs in plant roots during colonization by closely related beneficial and pathogenic fungi
Published in Nature communications (29-09-2016)“…Nature Communications 7 Article number:11362 (2016); Published 6 May 2016; Updated 29 September 2016. The HTML version of this Article previously published…”
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16
The genome sequence of the model ascomycete fungus Podospora anserina
Published in Genome Biology (01-01-2008)“…The dung-inhabiting ascomycete fungus Podospora anserina is a model used to study various aspects of eukaryotic and fungal biology, such as ageing, prions and…”
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17
SynteBase/SynteView: a tool to visualize gene order conservation in prokaryotic genomes
Published in BMC bioinformatics (16-12-2008)“…It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or…”
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18
Expression pattern of Brachyury in the mollusc Patella vulgata suggests a conserved role in the establishment of the AP axis in Bilateria
Published in Development (Cambridge) (15-03-2002)“…We report the characterisation of a Brachyury ortholog ( PvuBra ) in the marine gastropod Patella vulgata . In this mollusc, the embryo displays an equal…”
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19
A general framework for optimization of probes for gene expression microarray and its application to the fungus Podospora anserina
Published in BMC research notes (18-06-2010)“…The development of new microarray technologies makes custom long oligonucleotide arrays affordable for many experimental applications, notably gene expression…”
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20
Intergenic ORFs as elementary structural modules of de novo gene birth and protein evolution
Published in Genome research (01-12-2021)“…The noncoding genome plays an important role in de novo gene birth and in the emergence of genetic novelty. Nevertheless, how noncoding sequences' properties…”
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