Search Results - "Olivier, Jocelien D."
-
1
Slight and hidden hearing loss in young rats is associated with impaired recognition memory and reduced myelination in the corpus callosum
Published in Behavioral neuroscience (10-10-2024)“…Slight and hidden hearing loss in children have been linked to cognitive and social difficulties, and yet the neurobiological mechanisms behind these issues…”
Get full text
Journal Article -
2
Perinatal exposure to fluoxetine and maternal adversity affect myelin-related gene expression and epigenetic regulation in the corticolimbic circuit of juvenile rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2022)“…Many pregnant women experience symptoms of depression, and are often treated with selective serotonin reuptake inhibitor (SSRI) antidepressants, such as…”
Get full text
Journal Article -
3
Effects of perinatal fluoxetine exposure on novelty-induced social and non-social investigation behaviors in a seminatural environment
Published in Psychopharmacology (01-12-2021)“…Selective serotonin reuptake inhibitors (SSRIs) are increasingly prescribed as medication for various affective disorders during pregnancy. SSRIs cross the…”
Get full text
Journal Article -
4
Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring
Published in Psychopharmacologia (01-10-2011)“…Rationale Fluoxetine (Prozac®) is the most frequently prescribed drug to battle depression in pregnant women, but its safety in the unborn child has not yet…”
Get full text
Journal Article -
5
Perinatal fluoxetine exposure disrupts the circadian response to a phase-shifting challenge in female rats
Published in Psychopharmacology (01-08-2020)“…Rationale Selective serotonin reuptake inhibitor (SSRI) antidepressants are increasingly prescribed during pregnancy. Changes in serotonergic signaling during…”
Get full text
Journal Article -
6
Fluoxetine exerts age-dependent effects on behavior and amygdala neuroplasticity in the rat
Published in PloS one (31-01-2011)“…The selective serotonin reuptake inhibitor (SSRI) Prozac® (fluoxetine) is the only registered antidepressant to treat depression in children and adolescents…”
Get full text
Journal Article -
7
Perinatal fluoxetine treatment and dams’ early life stress history have opposite effects on aggressive behavior while having little impact on sexual behavior of male rat offspring
Published in Psychopharmacology (01-09-2020)“…Rationale Many depressed women continue antidepressant treatment during pregnancy. Selective serotonin reuptake inhibitor (SSRI) treatment during pregnancy…”
Get full text
Journal Article -
8
Editorial: The Complex Biopsychosocial Interactions That Create Stress Resilience
Published in Frontiers in behavioral neuroscience (22-11-2021)“…Besides early life adversity, natural disasters are likely to result in emotional disorders, including depression and posttraumatic stress disorder (PTSD)…”
Get full text
Journal Article -
9
Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats
Published in Psychopharmacologia (01-10-2008)“…Rationale While individual differences in vulnerability to psychostimulants have been largely attributed to dopaminergic neurotransmission, the role of…”
Get full text
Journal Article -
10
Serotonin Transporter Genotype Modulates the Gut Microbiota Composition in Young Rats, an Effect Augmented by Early Life Stress
Published in Frontiers in cellular neuroscience (03-08-2017)“…The neurotransmitter serotonin (5-HT) plays a vital regulatory role in both the brain and gut. 5-HT is crucial for regulating mood in the brain as well as…”
Get full text
Journal Article -
11
The Serotonin Transporter and Early Life Stress: Translational Perspectives
Published in Frontiers in cellular neuroscience (26-04-2017)“…The interaction between the serotonin transporter (SERT) linked polymorphic region (5-HTTLPR) and adverse early life stressing (ELS) events is associated with…”
Get full text
Journal Article -
12
A new approach to ‘on-demand’ treatment of lifelong premature ejaculation by treatment with a combination of a 5-HT1A receptor antagonist and SSRI in rats
Published in Frontiers in neuroscience (13-09-2023)“…Lifelong premature ejaculation (PE) in men lacks an adequate on-demand pharmacological treatment. Although selective serotonin reuptake inhibitors (SSRIs) are…”
Get full text
Journal Article -
13
Subjecting Dams to Early Life Stress and Perinatal Fluoxetine Treatment Differentially Alters Social Behavior in Young and Adult Rat Offspring
Published in Frontiers in neuroscience (12-03-2019)“…Recently, the putative association between selective serotonin reuptake inhibitor (SSRI) exposure during pregnancy and the development of social disorders in…”
Get full text
Journal Article -
14
Constitutive Serotonin Transporter Reduction Resembles Maternal Separation with Regard to Stress-Related Gene Expression
Published in ACS chemical neuroscience (17-07-2019)“…Interactive effects between allelic variants of the serotonin transporter (5-HTT) promoter-linked polymorphic region (5-HTTLPR) and stressors on depression…”
Get full text
Journal Article -
15
Pharmacological Studies on the Role of 5-HT1A Receptors in Male Sexual Behavior of Wildtype and Serotonin Transporter Knockout Rats
Published in Frontiers in behavioral neuroscience (31-03-2020)“…Brain serotonin (5-HT) neurotransmission plays an important role in male sexual behavior and it is well established that activating 5-HT1AR in rats facilitates…”
Get full text
Journal Article -
16
Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans
Published in Neurobiology of disease (01-03-2010)“…Abstract In order to identify the molecular mechanisms that may contribute to the enhanced susceptibility to depression under serotonin transporter (SERT)…”
Get full text
Journal Article -
17
Efficacy, Safety, and Tolerability of Psychedelics in Treatment-Resistant Depression (TRD)
Published in Advances in experimental medicine and biology (2024)“…Major depressive disorder (MDD) is a highly prevalent psychiatric disorder, associated with substantial burden and large economical costs. Notwithstanding…”
Get more information
Journal Article -
18
The role of the serotonergic and GABA system in translational approaches in drug discovery for anxiety disorders
Published in Frontiers in pharmacology (01-01-2013)“…There is ample evidence that genetic factors play an important role in anxiety disorders. In support, human genome-wide association studies have implicated…”
Get full text
Journal Article -
19
Effects of Fluoxetine on Human Embryo Development
Published in Frontiers in cellular neuroscience (16-06-2016)“…The use of antidepressant treatment during pregnancy is increasing, and selective serotonin reuptake inhibitors (SSRIs) are the most widely prescribed…”
Get full text
Journal Article -
20
The role of the dopamine D1 receptor in social cognition: studies using a novel genetic rat model
Published in Disease models & mechanisms (01-10-2016)“…Social cognition is an endophenotype that is impaired in schizophrenia and several other (comorbid) psychiatric disorders. One of the modulators of social…”
Get full text
Journal Article