Search Results - "Oliveira Aguiar‐Soares, Rodrigo Dian"
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Establishment of monoclonal antibodies to evaluate the cellular immunity in a hamster model of L infantum infection
Published in Parasite immunology (01-04-2021)“…Syrian hamsters (Mesocricetus auratus) are largely used as a model for infectious diseases because it is very susceptible to several pathogens, including…”
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Recent advances and new strategies in Leishmaniasis diagnosis
Published in Applied microbiology and biotechnology (01-10-2020)“…Leishmaniasis is a set of complex and multifaceted syndromes, with different clinical manifestations, caused by different species of the genus Leishmania spp…”
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Multiplex flow cytometry serology to diagnosis of canine visceral leishmaniasis
Published in Applied microbiology and biotechnology (01-10-2019)“…An accurate diagnosis of visceral leishmaniasis is an essential tool for control of the disease. While serologic methods are very useful, these conventional…”
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Antiproliferative and toxicogenomic effects of resveratrol in bladder cancer cells with different TP53 status
Published in Environmental and molecular mutagenesis (01-10-2019)“…The antitumor activity of resveratrol, a polyphenolic compound found mainly in grapes, has been studied in several types of cancer. In bladder cancer, its…”
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Evaluation of change in canine diagnosis protocol adopted by the visceral leishmaniasis control program in Brazil and a new proposal for diagnosis
Published in PloS one (07-03-2014)“…The techniques used for diagnosis of canine visceral leishmaniasis (CVL) in Brazil ELISA and IFAT have been extensively questioned because of the accuracy of…”
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A chimeric vaccine combined with adjuvant system induces immunogenicity and protection against visceral leishmaniasis in BALB/c mice
Published in Vaccine (12-05-2021)“…In Brazil, canine visceral leishmaniasis is an important public health problem due to its alarming growth. The high prevalence of infected dogs reinforces the…”
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Immunochemotherapy for visceral leishmaniasis: combinatorial action of Miltefosine plus LBSapMPL vaccine improves adaptative Th1 immune response with control of splenic parasitism in experimental hamster model
Published in Parasitology (01-03-2022)“…The control of human visceral leishmaniasis (VL) is hard since there are no vaccines available as well as the treatment is hampered by toxicity and resistant…”
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Prevalence and factors associated with Leishmania infantum infection of dogs from an urban area of Brazil as identified by molecular methods
Published in PLoS neglected tropical diseases (01-08-2011)“…Various factors contribute to the urbanization of the visceral leishmaniasis (VL), including the difficulties of implementing control measures relating to the…”
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The TcI and TcII Trypanosoma cruzi experimental infections induce distinct immune responses and cardiac fibrosis in dogs
Published in Memórias do Instituto Oswaldo Cruz (01-12-2014)“…Trypanosoma cruzi infection may be caused by different strains with distinct discrete typing units (DTUs) that can result in variable clinical forms of chronic…”
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Effect on cellular recruitment and the innate immune response by combining saponin, monophosphoryl lipid-A and Incomplete Freund’s Adjuvant with Leishmania (Viannia) braziliensis antigens for a vaccine formulation
Published in Vaccine (20-11-2019)“…The poor immunogenicity displayed by some antigens has encouraged the development of strategies to improve the immune response and safety of vaccine…”
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Antitumor effect of Cymbopogon densiflorus (Linneu) essential oil in bladder cancer cells
Published in Natural product research (02-12-2021)“…The aim of this study was to analyse the antitumor effect of the Cymbopogon densiflorus essential oil in silico and in vitro on bladder cancer cells RT4 and…”
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Clinical forms of canine visceral Leishmaniasis in naturally Leishmania infantum-infected dogs and related myelogram and hemogram changes
Published in PloS one (23-12-2013)“…Hematological analysis has limited applications for disease diagnosis in Leishmania infantum-infected dogs, but it can be very important in evaluating the…”
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Performance of LBSap vaccine after intradermal challenge with L. infantum and saliva of Lu. longipalpis: immunogenicity and parasitological evaluation
Published in PloS one (26-11-2012)“…In the last decade, the search for new vaccines against canine visceral leishmaniasis has intensified. However, the pattern related to immune protection during…”
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Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge
Published in PloS one (24-08-2016)“…Dogs represent the most important domestic reservoir of L. chagasi (syn. L. infantum). A vaccine against canine visceral leishmaniasis (CVL) would be an…”
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Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice
Published in Vaccines (Basel) (28-10-2019)“…Reverse vaccinology or immunoinformatics is a computational methodology which integrates data from in silico epitope prediction, associated to other important…”
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The Use of an Adjuvant System Improves Innate and Adaptive Immune Response When Associated with a Leishmania ( Viannia ) braziliensis Antigen in a Vaccine Candidate against L. ( Leishmania ) infantum Infection
Published in Vaccines (Basel) (09-02-2023)“…The adjuvants' optimal dose and the administration route can directly influence the epitope recognition patterns and profiles of innate response. We aimed to…”
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Evaluation of a Prototype Flow Cytometry Test for Serodiagnosis of Canine Visceral Leishmaniasis
Published in Clinical and Vaccine Immunology (01-12-2013)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunogenicity of a killed Leishmania vaccine with saponin adjuvant in dogs
Published in Vaccine (01-11-2007)“…Abstract Cellular and humoral immune responses of dogs to a candidate vaccine, composed of Leishmania braziliensis promastigote protein plus saponin as…”
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Canine visceral leishmaniasis biomarkers and their employment in vaccines
Published in Veterinary parasitology (01-07-2019)“…[Display omitted] •CD4+/ CD8+ T-cell (proinflammatory profile) is related with a resistance to CVL.•Polyclonal B-cell expansion is associated with high…”
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Mixed Formulation of Conventional and Pegylated Meglumine Antimoniate-Containing Liposomes Reduces Inflammatory Process and Parasite Burden in Leishmania infantum-Infected BALB/c Mice
Published in Antimicrobial agents and chemotherapy (01-11-2017)“…Pentavalent antimonial has been the first choice treatment for visceral leishmaniasis; however, it has several side effects that leads to low adherence to…”
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