Search Results - "Oliveira, Nélio A J"

Feeder-free derivation of induced pluripotent stem cells from human immature dental pulp stem cells by Beltrão-Braga, Patrícia C B, Pignatari, Graciela C, Maiorka, Paulo C, Oliveira, Nélio A J, Lizier, Nelson F, Wenceslau, Cristiane V, Miglino, Maria A, Muotri, Alysson R, Kerkis, Irina

“…Induced pluripotent stem cells (iPSCs) can be created by forcing expression of certain genes in fibroblasts or other somatic cell types, reversing them to a…”
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Expression, purification, and characterization of authentic mouse prolactin obtained in Escherichia coli periplasmic space by Suzuki, Miriam F., Arthuso, Fernanda S., Oliveira, João E., Oliveira, Nélio A. J., Goulart, Herbert R., Capone, Marcos V. N., Ribela, Maria Teresa C. P., Bartolini, Paolo, Soares, Carlos R. J.

“…Prolactin (PRL) is a pleiotropic hormone produced by lactotroph cells of the anterior pituitary gland and is mainly related to lactation control and…”
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Growth responses following a single intra-muscular hGH plasmid administration compared to daily injections of hGH in dwarf mice by Higuti, Eliza, Cecchi, Claudia R, Oliveira, Nelio A J, Vieira, Daniel P, Jensen, Thomas G, Jorge, Alexander A L, Bartolini, Paolo, Peroni, Cibele N

“…In previous work, sustained levels of circulating human growth hormone (hGH) and a highly significant weight increase were observed after electrotransfer of…”
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Apert p.Ser252Trp mutation in FGFR2 alters osteogenic potential and gene expression of cranial periosteal cells by Fanganiello, Roberto D, Sertié, Andréa L, Reis, Eduardo M, Yeh, Erika, Oliveira, Nélio A J, Bueno, Daniela F, Kerkis, Irina, Alonso, Nivaldo, Cavalheiro, Sérgio, Matsushita, Hamilton, Freitas, Renato, Verjovski-Almeida, Sergio, Passos-Bueno, Maria Rita

“…Apert syndrome (AS), a severe form of craniosynostosis, is caused by dominant gain-of-function mutations in FGFR2. Because the periosteum contribution to AS…”
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Efficient engraftment of pluripotent stem cell-derived myogenic progenitors in a novel immunodeficient mouse model of limb girdle muscular dystrophy 2I by Azzag, Karim, Ortiz-Cordero, Carolina, Oliveira, Nelio A J, Magli, Alessandro, Selvaraj, Sridhar, Tungtur, Sudheer, Upchurch, Weston, Iaizzo, Paul A, Lu, Qi Long, Perlingeiro, Rita C R

“…Defects in α-dystroglycan (DG) glycosylation characterize a group of muscular dystrophies known as dystroglycanopathies. One of the key effectors in the α-DG…”
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Further evidence of association between mutations in FGFR2 and syndromic craniosynostosis with sacrococcygeal eversion by Oliveira, Nélio A.J., Alonso, Luís G., Fanganiello, Roberto D., Passos‐Bueno, Maria Rita

“…BACKGROUND: Pfeiffer syndrome (PS; OMIM #101600) is an autosomal dominant disorder characterized by craniosynostosis, midface hypoplasia, broad thumbs,…”
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Long-term human growth hormone expression and partial phenotypic correction by plasmid-based gene therapy in an animal model of isolated growth hormone deficiency by Oliveira, Nélio A. J., Cecchi, Cláudia R., Higuti, Eliza, Oliveira, João E., Jensen, Thomas G., Bartolini, Paolo, Peroni, Cibele N.

“…Background A model for in vivo gene therapy based on electroporation of human growth hormone (hGH)‐coding naked DNA in the muscle of dwarf (lit/lit) and…”
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A universal gene correction approach for FKRP-associated dystroglycanopathies to enable autologous cell therapy by Dhoke, Neha R., Kim, Hyunkee, Selvaraj, Sridhar, Azzag, Karim, Zhou, Haowen, Oliveira, Nelio A.J., Tungtur, Sudheer, Ortiz-Cordero, Carolina, Kiley, James, Lu, Qi Long, Bang, Anne G., Perlingeiro, Rita C.R.

“…Mutations in the fukutin-related protein (FKRP) gene result in a broad spectrum of muscular dystrophy (MD) phenotypes, including the severe Walker-Warburg…”
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Partial correction of the dwarf phenotype by non-viral transfer of the growth hormone gene in mice: Treatment age is critical by Higuti, Eliza, Cecchi, Cláudia R, Oliveira, Nélio A.J, Lima, Eliana R, Vieira, Daniel P, Aagaard, Lars, Jensen, Thomas G, Jorge, Alexander A.L, Bartolini, Paolo, Peroni, Cibele N

“…Abstract Non-viral transfer of the growth hormone gene to different muscles of immunodeficient dwarf (lit/scid) mice is under study with the objective of…”
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A novel homologous model for gene therapy of dwarfism by non-viral transfer of the mouse growth hormone gene into immunocompetent dwarf mice by Cecchi, Claudia R, Higuti, Eliza, Oliveira, Nelio A J, Lima, Eliana R, Jakobsen, Maria, Dagnaes-Hansen, Frederick, Gissel, Hanne, Aagaard, Lars, Jensen, Thomas G, Jorge, Alexander A L, Bartolini, Paolo, Peroni, Cibele N

“…The possibilities for non-viral GH gene therapy are studied in immunocompetent dwarf mice (lit/lit). As expression vector we used a plasmid previously employed…”
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NAD+ enhances ribitol and ribose rescue of [alpha]-dystroglycan functional glycosylation in human FKRP-mutant myotubes by Ortiz-Cordero, Carolina, Magli, Alessandro, Dhoke, Neha R, Kuebler, Taylor, Selvaraj, Sridhar, Oliveira, Nelio AJ, Zhou, Haowen, Sham, Yuk Y, Bang, Anne G, Perlingeiro, Rita CR

“…Mutations in the fukutin-related protein (FKRP) cause Walker-Warburg syndrome (WWS), a severe form of congenital muscular dystrophy. Here, we established a WWS…”
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NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes by Ortiz-Cordero, Carolina, Magli, Alessandro, Dhoke, Neha R, Kuebler, Taylor, Selvaraj, Sridhar, Oliveira, Nelio Aj, Zhou, Haowen, Sham, Yuk Y, Bang, Anne G, Perlingeiro, Rita Cr

“…Mutations in the fukutin-related protein (FKRP) cause Walker-Warburg syndrome (WWS), a severe form of congenital muscular dystrophy. Here, we established a WWS…”
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Further evidence of association between mutations in FGFR2 and syndromic craniosynostosis with sacrococcygeal eversion by Oliveira, Nelio A J, Alonso, Luis G, Fanganiello, Roberto D, Passos-Bueno, Maria Rita

“…BACKGROUND: Pfeiffer syndrome (PS; OMIM #101600) is an autosomal dominant disorder characterized by craniosynostosis, midface hypoplasia, broad thumbs,…”
Get full text