Search Results - "Oliveira, Maureen"

Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir by QUASHIE, Peter K, MESPLEDE, Thibault, HAN, Ying-Shan, OLIVEIRA, Maureen, SINGHROY, Diane N, FUJIWARA, Tamio, UNDERWOOD, Mark R, WAINBERG, Mark A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Evaluation of Sofosbuvir (β-D-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine) as an inhibitor of Dengue virus replication by Xu, Hong-Tao, Colby-Germinario, Susan P., Hassounah, Said A., Fogarty, Clare, Osman, Nathan, Palanisamy, Navaneethan, Han, Yingshan, Oliveira, Maureen, Quan, Yudong, Wainberg, Mark A.

“…We evaluated Sofosbuvir (SOF), the anti-hepatitis C virus prodrug of β-d-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine-5′-monophosphate, for potential inhibitory…”
Get full text

Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir by Oliveira, Maureen, Ibanescu, Ruxandra-Ilinca, Anstett, Kaitlin, Mésplède, Thibault, Routy, Jean-Pierre, Robbins, Marjorie A, Brenner, Bluma G

“…Integrase strand transfer inhibitors (INSTIs) are recommended for first-line HIV therapy based on their relatively high genetic barrier to resistance. Although…”
Get full text

Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors by Xu, Hong-Tao, Hassounah, Said A, Colby-Germinario, Susan P, Oliveira, Maureen, Fogarty, Clare, Quan, Yudong, Han, Yingshan, Golubkov, Olga, Ibanescu, Ilinca, Brenner, Bluma, Stranix, Brent R, Wainberg, Mark A

“…The viral RNA-dependent RNA polymerase (RdRp) enzymes of the Flaviviridae family are essential for viral replication and are logically important targets for…”
Get full text

Development of a G118R mutation in HIV-1 integrase following a switch to dolutegravir monotherapy leading to cross-resistance to integrase inhibitors by Brenner, Bluma G, Thomas, Réjean, Blanco, José Luis, Ibanescu, Ruxandra-Ilinca, Oliveira, Maureen, Mesplède, Thibault, Golubkov, Olga, Roger, Michel, Garcia, Federico, Martinez, Esteban, Wainberg, Mark A

“…Dolutegravir shows a high barrier to resistance with no previously reported cases of acquired integrase mutations during first-line therapy. In this study,…”
Get full text

Compensation by the E138K Mutation in HIV-1 Reverse Transcriptase for Deficits in Viral Replication Capacity and Enzyme Processivity Associated with the M184I/V Mutations by XU, Hong-Tao, ASAHCHOP, Eugene L, OLIVEIRA, Maureen, QUASHIE, Peter K, YUDONG QUAN, BRENNER, Bluma G, WAINBERG, Mark A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase by Xu, Hong-Tao, Colby-Germinario, Susan P, Hassounah, Said, Quashie, Peter K, Han, Yingshan, Oliveira, Maureen, Stranix, Brent R, Wainberg, Mark A

“…The viral RNA-dependent RNA polymerase (RdRp) activity of the dengue virus (DENV) NS5 protein is an attractive target for drug design. Here, we report the…”
Get full text

Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and Their Interactions with the M184I Mutation on Defining Patterns of Resistance to Nonnucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine by XU, Hong-Tao, COLBY-GERMINARIO, Susan P, ASAHCHOP, Eugene L, OLIVEIRA, Maureen, MCCALLUM, Matthew, SCHADER, Susan M, YINGSHAN HAN, YUDONG QUAN, SARAFIANOS, Stefan G, WAINBERG, Mark A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Phylogenetic Network Analyses Reveal the Influence of Transmission Clustering on the Spread of HIV Drug Resistance in Quebec from 2002 to 2022 by Brenner, Bluma G, Ibanescu, Ruxandra-Ilinca, Oliveira, Maureen, Margaillan, Guillaume, Lebouché, Bertrand, Thomas, Réjean, Baril, Jean Guy, Lorgeoux, René-Pierre, Roger, Michel, Routy, Jean-Pierre, The Montreal Primary Hiv Infection Phi Cohort Study Group

“…HIV drug resistance (HIV-DR) may jeopardize the benefit of antiretroviral therapy (ART) in treatment and prevention. This study utilized viral phylogenetics to…”
Get full text

The Role of Phylogenetics in Unravelling Patterns of HIV Transmission towards Epidemic Control: The Quebec Experience (2002-2020) by Brenner, Bluma G, Ibanescu, Ruxandra-Ilinca, Osman, Nathan, Cuadra-Foy, Ernesto, Oliveira, Maureen, Chaillon, Antoine, Stephens, David, Hardy, Isabelle, Routy, Jean-Pierre, Thomas, Réjean, Baril, Jean-Guy, Leblanc, Roger, Tremblay, Cecile, Roger, Michel, The Montreal Primary Hiv Infection Phi Cohort Study Group

“…Phylogenetics has been advanced as a structural framework to infer evolving trends in the regional spread of HIV-1 and guide public health interventions. In…”
Get full text

Identification of Novel Mutations Responsible for Resistance to MK-2048, a Second-Generation HIV-1 Integrase Inhibitor by Bar-Magen, Tamara, Sloan, Richard D, Donahue, Daniel A, Kuhl, Björn D, Zabeida, Alexandra, Xu, Hongtao, Oliveira, Maureen, Hazuda, Daria J, Wainberg, Mark A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

In Vitro Resistance Profile of the Candidate HIV-1 Microbicide Drug Dapivirine by Schader, Susan M, Oliveira, Maureen, Ibanescu, Ruxandra-Ilinca, Moisi, Daniela, Colby-Germinario, Susan P, Wainberg, Mark A

“…Antiretroviral-based microbicides may offer a means to reduce the sexual transmission of HIV-1. Suboptimal use of a microbicide may, however, lead to the…”
Get full text

Template Usage Is Responsible for the Preferential Acquisition of the K65R Reverse Transcriptase Mutation in Subtype C Variants of Human Immunodeficiency Virus Type 1 by COUTSINOS, Dimitrios, INVERNIZZI, Cédric F, HONGTAO XU, MOISI, Daniela, OLIVEIRA, Maureen, BRENNER, Bluma G, WAINBERG, Mark A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Characterization of the E138K Resistance Mutation in HIV-1 Reverse Transcriptase Conferring Susceptibility to Etravirine in B and Non-B HIV-1 Subtypes by ASAHCHOP, Eugene L, OLIVEIRA, Maureen, WAINBERG, Mark A, BRENNER, Bluma G, MOISI, Daniela, D'AQUIN TONI, Thomas, TREMBLAY, Cecile L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Distinct resistance patterns to etravirine and rilpivirine in viruses containing nonnucleoside reverse transcriptase inhibitor mutations at baseline by ASAHCHOP, Eugene L, WAINBERG, Mark A, OLIVEIRA, Maureen, HONGTAO XU, BRENNER, Bluma G, MOISI, Daniela, IBANESCU, Ilinca R, TREMBLAY, Cecile

“…The current in-vitro study examined HIV-1 drug resistance patterns following etravirine (ETR) and rilpivirine (RPV) drug pressure in viruses containing…”
Get full text

A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to non-nucleoside reverse transcriptase inhibitors by BRENNER, Bluma, TURNER, Dan, OLIVEIRA, Maureen, MOISI, Daniela, DETORIO, Mervi, CAROBENE, Mauricio, MARLINK, Richard G, SCHAPIRO, Jonathan, ROGER, Michel, WAINBERG, Mark A

“…We have shown that HIV-1 clade C variants contain a valine codon 106 polymorphism (GTG) that facilitates a V106M transition (GTG<--ATG) after selection with…”
Get full text

High Prevalence of the K65R Mutation in Human Immunodeficiency Virus Type 1 Subtype C Isolates from Infected Patients in Botswana Treated with Didanosine-Based Regimens by DOUALLA -BELL, Florence, AVALOS, Ava, ESSEX, Max, WAINBERG, Mark A, BRENNER, Bluma, GAOLATHE, Tendani, MINE, Madisa, GASEITSIWE, Simani, OLIVEIRA, Maureen, MOISI, Daniella, NDWAPI, Ndwapi, MOFFAT, Howard

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

HIV gp120 H375 Is Unique to HIV-1 Subtype CRF01_AE and Confers Strong Resistance to the Entry Inhibitor BMS-599793, a Candidate Microbicide Drug by SCHADER, Susan M, COLBY-GERMINARIO, Susan P, QUASHIE, Peter K, OLIVEIRA, Maureen, IBANESCU, Ruxandra-Ilinca, MOISI, Daniela, MESPLEDE, Thibault, WAINBERG, Mark A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

The Connection Domain Mutation N348I in HIV-1 Reverse Transcriptase Enhances Resistance to Etravirine and Rilpivirine but Restricts the Emergence of the E138K Resistance Mutation by Diminishing Viral Replication Capacity by Xu, Hong-Tao, Colby-Germinario, Susan P, Oliveira, Maureen, Han, Yingshan, Quan, Yudong, Zanichelli, Veronica, Wainberg, Mark A

“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1 by Coutsinos, Dimitrios, Invernizzi, Cédric F, Moisi, Daniela, Oliveira, Maureen, Martinez-Cajas, Jorge L, Brenner, Bluma G, Wainberg, Mark A

“…Numerous studies have suggested that the K65R reverse transcriptase (RT) mutation develops more readily in subtype C than subtype B HIV-1. We recently showed…”
Get full text