Search Results - "Oliveira, Marcelio"
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Streptococcus agalactiae serotype Ia capsular polysaccharide production from a Brazilian strain
Published in Carbohydrate polymer technologies and applications (01-06-2024)“…The pathogen S. agalactiae, categorized as Lancefield group B streptococci (GBS), is a Gram-positive bacterium, encapsulated, anaerobic facultative bacillus,…”
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Preliminary SAR analysis of novel antiproliferative N 6,5′-bis-ureidoadenosine derivatives
Published in Bioorganic & medicinal chemistry letters (01-12-2009)“…Analogs of lead antiproliferative agent 1 were prepared and tested for activities against the NCI 60 panel of human cancers. Variants in all four canonical…”
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Synthesis, SAR, and preliminary mechanistic evaluation of novel antiproliferative N6,5′-bis-ureido- and 5′-carbamoyl-N6-ureidoadenosine derivatives
Published in Bioorganic & medicinal chemistry (15-01-2012)“…R=Phenyl, p-chlorophenyl, p-iodophenyl, m-iodophenyl, p-nitrophenyl, p-methoxyphenyl, benzyl, propyl, hexyl, cyclohexyl. We have developed efficient methods…”
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Preliminary SAR analysis of novel antiproliferative N(6),5'-bis-ureidoadenosine derivatives
Published in Bioorganic & medicinal chemistry letters (01-12-2009)“…A preliminary library of novel N(6),5'-bis-ureidoadenosine analogs and related derivatives was prepared and tested for activity against the NCI 60 panel of…”
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Antiproliferative and Protein Kinase Binding Activities of Some N 6, 5′-bis-ureido 5′-Amino-5′-Deoxyadenosine Derivatives
Published in Nucleosides, nucleotides & nucleic acids (11-08-2009)“…Two novel N 6 ,5′-bis-ureido 5′-amino-5′-deoxyadenosine derivatives are shown to inhibit tumor cell growth in the NCI 60 human tumor cell panel. Compounds 2c…”
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Preliminary SAR analysis of novel antiproliferative N6,5'-bis-ureidoadenosine derivatives
Published in Bioorganic & medicinal chemistry letters (01-12-2009)Get full text
Journal Article -
8
Antiproliferative and protein kinase binding activities of Some N6, 5'-bis-ureido 5'-amino-5'-deoxyadenosine derivatives
Published in Nucleosides, nucleotides & nucleic acids (01-05-2009)“…Two novel N(6),5'-bis-ureido 5'-amino-5'-deoxyadenosine derivatives are shown to inhibit tumor cell growth in the NCI 60 human tumor cell panel. Compounds 2c…”
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Journal Article -
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Synthesis and Evaluation of N6,5'-Bis-Ureido-5'-Amino-5'-Deoxyadenosine Derivatives: Novel Nucleosides with Antiproliferative and Protein Kinase Binding Activities
Published 01-01-2009“…A new series of N6,5'-bis-ureido-5'-amino-5'-deoxyadenosine derivatives was prepared and evaluated for anticancer activities using the NCI 60 panel of human…”
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Dissertation