Search Results - "Oliveira, Márcia R."

Antileishmanial activity of new thiophene–indole hybrids: Design, synthesis, biological and cytotoxic evaluation, and chemometric studies by Félix, Mayara B., de Souza, Edson R., de Lima, Maria do C.A., Frade, Daiana Karla G., Serafim, Vanessa de L., Rodrigues, Klinger Antonio da F., Néris, Patrícia Lima do N., Ribeiro, Frederico F., Scotti, Luciana, Scotti, Marcus T., de Aquino, Thiago M., Mendonça Junior, Francisco Jaime B., de Oliveira, Márcia R.

“…[Display omitted] •32 hybrid thiophene–indolyl derivatives were synthesized and characterized.•Various compounds showed good antileishmanial activity (IC50…”
Get full text

Improved synthesis of seven aromatic Baylis–Hillman adducts (BHA): Evaluation against Artemia salina Leach. and Leishmania chagasi by Barbosa, Ticiano P., Junior, Cláudio G.L., Silva, Fábio P.L., Lopes, Horacimone M., Figueiredo, Lucas R.F., Sousa, Suervy C.O., Batista, Guilherme N., da Silva, Thiago G., Silva, Tania M.S., de Oliveira, Márcia R., Vasconcellos, Mário L.A.A.

“…We described a very efficient procedure to prepare seven aromatic compounds ( 1– 7), a new class of antileishmanial substances, through Baylis–Hillman reaction…”
Get full text

Antibacterial and antiparasitic effects of Bothropoides lutzi venom by de Menezes, Ramon R P P B, Torres, Alba F C, da Silva, Thiala S J, de Sousa, Daniel F, Lima, Danya B, Norjosa, Diva B, Nogueira, Nádia A P, Oliveira, Maria F, de Oliveira, Márcia R, Monteiro, Helena S A, Martins, Alice M C

“…The therapeutic potential of toxins has aroused great interest in the scientific community. Microbial resistance is a serious current public health problem, in…”
Get more information

Design, synthesis and antileishmanial in vitro activity of new series of chalcones-like compounds: A molecular hybridization approach by Barbosa, Ticiano P., Sousa, Suervy C.O., Amorim, Francianne M., Rodrigues, Yara K.S., de Assis, Priscilla A.C., Caldas, John P.A., Oliveira, Márcia R., Vasconcellos, Mário L.A.A.

“…The chalcone-like series 1a–1g was efficiently synthesized from Morita–Baylis–Hillman reaction (52–74% yields). Compounds 1a–1g were designed by molecular…”
Get full text

Neolignan Licarin A presents effect against Leishmania (Leishmania) major associated with immunomodulation in vitro by Néris, Patrícia L.N., Caldas, John P.A., Rodrigues, Yara K.S., Amorim, Francianne M., Leite, Jacqueline A., Rodrigues-Mascarenhas, Sandra, Barbosa-Filho, José M., Rodrigues, Luis C., Oliveira, Márcia R.

“…•Licarin A inhibits the proliferation of Leishmania (L.) major promastigotesin vitro.•This neolignan induces DNA fragmentation on L. (L.) major…”
Get full text

Morphological and physiological changes in Leishmania promastigotes induced by yangambin, a lignan obtained from Ocotea duckei by Neto, Rubens L. Monte, Sousa, Louisa M.A., Dias, Celidarque S., Filho, José M. Barbosa, Oliveira, Márcia R., Figueiredo, Regina C.B.Q.

“…We have previously demonstrated that yangambin, a lignan obtained from Ocotea duckei Vattimo (Lauraceae), shows antileishmanial activity against promastigote…”
Get full text

Synthesis, evaluation against Leishmania amazonensis and cytotoxicity assays in macrophages of sixteen new congeners Morita–Baylis–Hillman adducts by Silva, Fábio P.L., de Assis, Priscilla A.C., Junior, Claudio G.L., de Andrade, Natália G., da Cunha, Saraghina M.D., Oliveira, Márcia R., Vasconcellos, Mário L.A.A.

“…We report the design, synthesis, in vitro evaluation against Leishmania amazonensis (IC 50), cytotoxicity assays in macrophages (CC 50), and selectivity index…”
Get full text

Efficient synthesis of 16 aromatic Morita–Baylis–Hillman adducts: Biological evaluation on Leishmania amazonensis and Leishmania chagasi by Junior, Cláudio G.L., de Assis, Priscila A.C., Silva, Fábio P.L., Sousa, Suervy C.O., de Andrade, Natália G., Barbosa, Ticiano P., Nerís, Patrícia L.N., Segundo, Luiz V.G., Anjos, Ítalo C., Carvalho, Gabriel A.U., Rocha, Gerd B., Oliveira, Márcia R., Vasconcellos, Mário L.A.A.

“…We described “one-pot” Morita-Baylis-Hillman reactions to produced 16 aromatic compounds (81-100%), its bio-evaluations on L. Amazonensis and L. chagasi and a…”
Get full text

Yangambin Cytotoxicity: A Pharmacologically Active Lignan Obtained from Ocotea duckei Vattimo (Lauraceae) by Monte Neto, Rubens L., Sousa, M. A., Dias, Celidarque S., Barbosa Filho, José M., Oliveira, Márcia R.

“…The in vitro cytotoxic potential of yangambin was evaluated. Yangambin is a pharmacologically active furofuran lignan obtained from the leaves of Ocotea…”
Get full text

Anti-mitotic activity towards sea urchin eggs of dichloromethane fraction obtained from Allamanda schottii Pohl (Apocynaceae) by Sousa, Louisa M. A., Monte Neto, Rubens L., Schmidt, Dionezine F. Navarro, Oliveira, Márcia R.

“…Allamanda (Apocynaceae) is a genus of climbing shrubs known for producing compounds with a range of biological activities. Previous works have shown the…”
Get full text

Crude Ethanolic Extract, Lignoid Fraction and Yangambin from Ocotea duckei (Lauraceae) Show Antileishmanial Activity by Monte Neto, Rubens L., Barbosa Filho, José M., A. Sousa, Louisa M., Athayde Filho, Petrônio F., Dias, Celidarque S., Oliveira, Márcia R.

“…Crude ethanolic extract, lignoid fraction and the purified compound yangambin were obtained from Ocotea duckei (Lauraceae) and their antileishmanial activity…”
Get full text

Evaluation of wound healing effect of alginate films containing Aloe vera (Aloe barbadensis Miller) gel by Koga, Adriana Y, Pereira, Airton V, Lipinski, Leandro C, Oliveira, Marcia RP

“…A new alginate dressing with Aloe vera gel was developed and used to study its cutaneous healing effect in vivo by surgical wounds in Wistar rats. The…”
Get full text

Kinetic resolution of leishmanicidal meta and para (±)-2-[Hydroxy(nitrophenyl)methyl]acrylonitrile catalyzed by CALB: In vitro evaluations of separated meta (R), (S) and (R/S) adducts by Xavier, Francisco J.S., Neto, José S.S., Néris, Patrícia L.N., Oliveira, Marcia R., Vale, Juliana A., Vasconcellos, Mario L.A.A.

“…•MBHA racemates employing the lipase B from Candida antarctica.•MTPA Mosher's procedure was used to determine the absolute configurations.•Investigation of the…”
Get full text

Risk Factors Associated to Stroke in Patients With Pacemakers and Implantable Cardioverter Defibrillator at an Outpatient Clinic in the City of Salvador, Bahia, Brazil by Sampaio, Elieusa, MD, Júnior, Roque Aras, PhD, Matta, José Alberto da, PhD, Macedo, Cristiano, MD, Oliveira, Márcia Maria, RN, dos Santos Júnior, Ubiratan, MS, Câmara, Sérgio, MS

Get full text

Attributable mortality due to nosocomial sepsis in Brazilian hospitals: a case–control study by Zampieri, Fernando G., Cavalcanti, Alexandre B., Taniguchi, Leandro U., Lisboa, Thiago C., Serpa-Neto, Ary, Azevedo, Luciano C. P., Nassar, Antonio Paulo, Miranda, Tamiris A., Gomes, Samara P. C., de Alencar Filho, Meton S., da Silva, Rodrigo T. Amancio, Lacerda, Fabio Holanda, Veiga, Viviane Cordeiro, de Oliveira Manoel, Airton Leonardo, Biondi, Rodrigo S., Maia, Israel S., Lovato, Wilson J., de Oliveira, Claudio Dornas, Pizzol, Felipe Dal, Filho, Milton Caldeira, Amendola, Cristina P., Westphal, Glauco A., Figueiredo, Rodrigo C., Caser, Eliana B., de Figueiredo, Lanese M., de Freitas, Flávio Geraldo R., Fernandes, Sergio S., Gobatto, Andre Luiz N., Paranhos, Jorge Luiz R., de Melo, Rodrigo Morel V., Sousa, Michelle T., de Almeida, Guacyra Margarita B., Ferronatto, Bianca R., Ferreira, Denise M., Ramos, Fernando J. S., Thompson, Marlus M., Grion, Cintia M. C., Santos, Renato Hideo Nakagawa, Damiani, Lucas P., Machado, Flavia R.

“…Background Nosocomial sepsis is a major healthcare issue, but there are few data on estimates of its attributable mortality. We aimed to estimate attributable…”
Get full text

Dielectric properties of papaya seeds from 75 kHz to 5 MHz by Berbert, Pedro, Soares, Karina, Moura, Eros, Berbert-Molina, Marília, Oliveira, Marcia, Martinazzo, Ana

Get full text