Acute lymphocytic leukemia associated with toxoplasmosis: case report

Acute lymphocytic leukemia associated with toxoplasmosis: case report

ABSTRACT Rare clinical case of acute lymphocytic leukemia (ALL) associated with toxoplasmosis affecting a 23-year-old male patient with progressive dyspnea. Chest computed tomography revealed expansive lesions indicating right supraclavicular fossa lymph node enlargement and right pleural effusion....

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Bibliographic Details
Published in:Jornal brasileiro de patologia e medicina laboratorial Vol. 56
Main Authors: Machado, Silmara, Oliveira, Leonardo R. G., Scalassara, Beatriz M., Faria, Karina G., Almeida, Lara E. F. O.
Format: Journal Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2020
Subjects:
derrame pleural
inmunohistoquímica
leucemia-linfoma linfoblástico de células precursoras
MEDICAL LABORATORY TECHNOLOGY
MEDICINE, RESEARCH & EXPERIMENTAL
PATHOLOGY
toxoplasmosis
toxoplasmose
derrame pleural
precursor cell lymphoblastic leukemia-lymphoma
toxoplasmosis
inmunohistoquímica
immunohistochemistry
pleural effusion
leucemia-linfoma linfoblástico de células precursoras
imuno-histoquímica
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Summary:ABSTRACT Rare clinical case of acute lymphocytic leukemia (ALL) associated with toxoplasmosis affecting a 23-year-old male patient with progressive dyspnea. Chest computed tomography revealed expansive lesions indicating right supraclavicular fossa lymph node enlargement and right pleural effusion. Toxoplasmosis serology was performed: positive for immunoglobulin G [(IgG) 180.6] and positive for immunoglobulin M [(IgM) 0.98]. Therefore, treatment for the infection was initiated and immunohistochemistry of left cervical lymph node revealed ALL. Consequently, chemotherapy treatment was introduced at an oncology center. The diagnosis of toxoplasmosis allowed treatment to be administered, preventing the worsening of the condition caused by chemotherapy-induced immunosuppression.
ISSN:1676-2444
1678-4774
1678-4774
DOI:10.5935/1676-2444.20200033